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HIGHLIGHTS Several ethephon concentrations were applied in pre-harvest on Japanese plums. The quality characteristics of the plums prior and after cold storage were evaluated. Ethephon use hastened the ripening of the fruits, with no effect in overall yield. Some quality characteristics were influenced by ethephon, both in harvest and after storage.

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HIGHLIGHTS Ruditapes decussatus from four sites belonging to Monastir bay (Tunisia) was first time analyzed based on morphometry and comparative statistics. The site of Ksiba was distinguishable from other sites by larger and heavier specimens. The sub-trapezoidal shape was dominant with small- size classes, in most sites. The principal component analysis (PCA) revealed different population groups, with two intra-population groups for Sokrine site. Allometric relationships showed highly significant correlation with different growth patterns (positive allometric, negative allometric and isometric).

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HIGHLIGHTS The fungicides in the laboratory experiment impaired root colonization of R. irregularis. In the greenhouse experiment, fungicides had no negative effect on root colonization of R. irregularis. The benomyl in maize and tilt in wheat and rovral TS in both plants could be recommended with the combined application of R. irregularis. Depending on fungicide type and host plant, the effect of fungicide on R. irregularis varies.

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HIGHLIGHTS Three species of Cucurbitaceae family are evaluated against the salt stress. Higher levels of salinity have more adverse effects on the growth of cucurbits. The varieties of bottle gourd performed well against the salt stress.

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HIGHLIGHTS Macrophomina phaseolina was for the first time detected on globe artichoke in the world. Polyphagous nature of M. phaseolina was confirmed on nine plant species using pathogenicity tests. Toothpick inoculation technique could be used for screening resistance to M. phaseolina.

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HIGHLIGHTS Biochar from sewage sludge (SS) was produced and characterized. Pyrolysis increased organic and total carbon. Pyrolysis increased micro and macronutrients concentration with exception of K. Biochar preserved the mineralogical characteristics of the raw material. Pyrolysis is an excellent alternative to transform SS into organic fertilizer.

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HIGHLIGHTS The diazotrophic endophytic community found in stems were different those found in leaves of sugarcane. Endophytes with valuable biochemical traits have been identified in the sugarcane tissues. A unique symbiotic consortium between endophytes were identified in the sugarcane tissues.

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HIGHLIGHTS A detailed description and illustration of stage-specific morphological characters of whiteflies Bemisia tabaci (Asia II 5) and Trialeurodes vaporariorum. Developmental biology of the whiteflies Bemisia tabaci (Asia II 5) and Trialeurodes vaporariorum. Preliminary information for field-level identification and the formulation of IPM strategies. First of its kind comparative study of morphology and biology of whiteflies in the Northwestern Himalayan region.

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HIGHLIGHTS Cytological study for floral malady in soybean MSAP profiling in floral malady symptomatic and asymptomatic plant. Insights of pattern and extent of methylation. Epigentic gene regulation by MSAP approach.

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HIGHLIGHTS Tissue culture technique is considered to be one of the best methods to reproduce salvia plant. Salvia is a medicinal plant with lots of chemical constituents. Salvia plays an important role in treating different fatal diseases. Maximum fresh and dry weights were obtained at 1.5 mg L-1 melatonin. the highest DPPH scavenging activity, total phenolics and flavonoid content were obtained at 1.5 mg L-1 melatonin.

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HIGHLIGHTS Overall, N, P, K contents were higher in leaves during flowering and then depleted during fruit development stages. Nitrogen content was found higher in Coratina among four olive cultivars Leaf phosphorus and potassium content was observed higher in Ottobratica and Leccino cultivars.

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Abstract: Yerba mate (Ilex paraguariensis St. Hill.) is an important woody tree in South America, however the production of quality seedlings is a major problem. Microorganisms that promote plant growth have shown to be efficient biotechnologies in the production of seedlings. The arbuscular mycorrhizal fungi (AMF), it establishes symbiosis with several plant species and increases the accumulation of biomass and absorption of poorly mobile nutrients such as phosphorus. Here, we test the effects of two AMF species on growth, root architecture, phosphorus accumulation and gas exchange of yerba mate seedlings cultivated under different phosphorus levels. We used seedlings in a non-sterile soil, inoculated with AMFs Rhizophagus clarus SCT720A and Acaulospora colombiana SCT115A, and non-inoculated (control) treatment under five levels of phosphorus (0; 25; 50; 100 and 200% recommendation). After 90 days of AMF inoculation, plant dry biomass, root architecture and mycorrhizal colonization were determined and after 180 days, the same parameters plus photosynthetic rate, transpiration rate, stomatal conductance and P content were evaluated. AMF inoculation increased shoot and root dry biomass, total root length, root volume. Plants inoculated with AMF showed higher photosynthesis rate. Phosphorus content and mycorrhizal colonization were increased almost three times when inoculated with AMF. Our findings highlight the importance of AMF inoculation for Ilex paraguariensis seedlings production, reducing the time needed in nurseries to enhance tree performance.

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Abstract: Erythroxylum pauferrense Plowman is an understory species native to Brazil, with great importance in the conservation of genetic resources and is used as a food source for animals in the regions where the species occurs. The species is currently listed in category EN (endangered). The objective of this work was to evaluate the effect of different substrates on the emergence and initial growth of E. pauferrense. The experiment was carried out in a protected environment, belonging to the Plant Ecology Laboratory of the Federal University of Paraíba, Areia-PB, Brazil. The substrates used were: sand; sand + vermiculite in the proportion of 1:1, 3:1 and 1:3; vegetal land; vegetal land + sand in the proportion of 1:1, 3:1 and 1:3; vegetal land + vermiculite in the proportion of 1:1, 3:1 and 1:3; vermiculite; Bioplant®; and Bioplant® + sand in a ratio of 1:1, 3:1 and 1:3. The experimental design was completely randomized, with 16 treatments (substrates) and four replications of 25 seeds. The percentage of emergence, first count, speed index, mean time, mean speed and relative emergency frequency were evaluated. The vermiculite substrate provided the best results for carrying out the emergence and vigor tests of E. pauferrense seedlings, being the most suitable substrate to initial growth seedlings of the species.

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Abstract: Given the lack of information on the use of controlled-release fertilizers in yerba mate seedlings production, this study aimed to evaluate growth and morphological characteristics of seedlings produced with two controlled-release fertilizers applied at different doses. We used seeds from a clonal seed orchard, which were sown in a commercial substrate based on peat and vermiculite, with Osmocote® MiniPrill 3M (CRF 3M) and Basacote® Plus 9M (CRF 9M) fertilizers, both in doses of 0, 2, 4, 6, 8, 10, and 12 kg m-3. Seedling height and stem diameter were measured at 60, 90, 120, and 180 days after sowing and, at 180 days, shoot, root, and total biomass, tube withdrawal ease, and root aggregation. From these data, we calculated Dickson's quality index, technical efficiency, Height/Stem diameter ratio, and maximum technical efficiency dose. We verified values statistically superior to control treatment (0 kg m-3) in all variables in response to controlled-release fertilizer 3M and 9M, demonstrating the viability of yerba mate seedling production using controlled-release fertilizers. This is also evidenced through results obtained for growth in height and stem diameter. Although CRF 3M favored seedling growth, CRF 9M showed similar efficiency. The Osmocote® MiniPrill 3M is more efficient than Basacote® Plus 9M in most of the variables analyzed and has a lower input required to obtain quality seedlings. For these reasons, Osmocote® MiniPrill 3M is indicated to produce yerba mate seedlings in the dose 8.50 kg m-3.

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HIGHLIGHTS Trichoderma spp. and Bacillus subtilis reduced colonial growth of Streptomyces sp. Trichoderma spp. and Bacillus subtilis reduced scab damage in potato tuber.

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HIGHLIGHTS This manuscript highlights the application of fenoxycarb for the effective control of cotton mealybug. Use of sub-lethal dosage to evaluate the resistance development of insecticide. These results can be helpful for the dose selection during control in the fields, so that resistance can be reduced against pesticides.

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HIGHLIGHTS Characterization of fruits of the Brazilian biodiversity. Potential alternative fruits that provide health benefits. Spreading information that stimulates valorization of the Brazilian biodiversity.

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HIGHLIGHTS G. lucidum is able to grow in a low-cost complex medium in a stirred tank bioreactor. KLa values between 17.3 - 32.8 h-1 are suitable to scale up bioprocess using complex media. Oxygen availability in the bioreactor affects the biomass and biomolecules production.

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HIGHLIGHTS Irrigation intervals over 8 days compromise the physiology of passion fruit. Passion fruit seedlings grafted into seedlings obtained by cuttings or seeds have greater vigor. Passion fruit seedlings propagated by seeds show greater efficiency in the use of water. Propagation methods influence the development of passion fruit.

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HIGHLIGHTS Biphasic liquid-liquid extraction of L. delbrueckii BS from the broth is executed. Extraction parameters are optimized and partition coefficient calculated. Co-current and countercurrent extraction of BS increased its yield. Purified BS characterized as glycoprotein/polymeric.

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HIGHLIGHTS Increase in the number of agribusiness biotechnology patents. Development of science, technology and innovation in the context of measuring economic growth. Increase in the number of patents and better results in agricultural productivity in the field.

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HIGHLIGHTS GSH may be produced by Saccharomyces cerevisiae in an airlift bioreactor. The higher the pressure, the higher GSH and biomass concentrations. The highest level of GSH concentration was 178.72 mg L-1 at 0.05 MPa after 96 h.

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HIGHLIGHTS Straw-based media are more suitable for Hypsizygus ulmarius cultivation Grape pomace and green walnut husks are useable as alternative supplement materials These harmful wastes are converted into functional foods by mushroom cultivation

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HIGHLIGHTS Bacillus sp (HCYL03) was capable of producing phytases under solid-state fermentation. Wheat bran, residue of the rolled milled wheat grain, showed, indeed, potential to be used in phytases production. Using wheat bran to attain bioproducts can reduce some social/environmental issues.

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HIGHLIGHTS RP-HPLC-PDA method was developed for the simultaneous determination of 25 phenolic compounds. The reliability of the developed method was confirmed by the validation test. An HPLC method has been developed to quantify phenolic acid and flavonoids in some bee products. The method showed good results in a run time of only 60 min.

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HIGHLIGHTS Trichoderma inoculation increased the total biomass, seedling height, root length, root area, root diameter, number of root tips, and number growth potential of seedlings. Trichoderma inoculation increases the resistance of bean plant to Rhizoctonia pathogen. Among improved isolates of Trichoderma, the ChBD13 and ChBD15 showed better performance in terms of plant growth.

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HIGHLIGHTS Subcoccinella vigintiquatuorpunctata is one of the main pest on alfalfa. Age-specific life table and survival rate for each life stage was calculated by using TWOSEX-MSChart. This study suggest the life table can be used for the biology and control of the alfalfa pest.

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HIGHLIGHTS Bacillus thuringiensis SP7-1 from agricultural soils producing polyhydroxyalkanoate. The strains SP7-1 with a PHA accumulation of 0.54 g/L and 19 % in dry biomass. PHA was characterized with FTIR, DSC and TGA with remarkable chemical properties. A thermic degradation in a range of 270-303°C and a Melting Temperature of 166.88°C.

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HIGHLIGHTS Water stress compromises seed germination. C. spectabilis tolerates up to an osmotic potential of -0.2 MPa. The temperature range between 25 and 30 ºC favors germination.

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HIGHLIGHTS The application of Ca or B does not affect the germination of zucchini seeds. The application of Ca in zucchini increases the number of pollen grains per flower. The production of zucchini seeds is favored by the application of Ca.

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HIGHLIGHTS First report showing optimization study of arginase production by Lactobacillus acidophilus. Optimization by OVAT approach resulted in four-fold enhanced arginase production. Response surface methodology resulted in six-fold enhanced arginase production with 15 mM arginine, 1% Yeast extract and medium pH 5.5.

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HIGHLIGHTS IRRI has launched their flagship project-4 consisting of ‘Antenna Panel’. ‘Antenna panel’ genotypes characterize evolving climate-dynamics through crop’s eye. SAHEL 108 is the most superior genotype for grain yield over all the three environments of testing.

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HIGHLIGHTS Bioceramic nanoparticles are used to replace hard tissues. The toxicity of β-TCP and BCP nanoparticles is not dependent on particle size. BCP nanoparticles exhibit greater cytotoxic and genotoxic properties at higher concentrations as compared to β-TCP nanoparticles. β-TCP and BCP cause oxidative stress depending on the increase in concentration. Oxidative stress causes cell death and DNA damage.

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HIGHLIGHTS V. tricolor ameliorates memory impairment caused by immobilization in rats. V. tricolor diminishes anxiety- and depression-like behaviors in immobilized rats. V. tricolor decreases chronic immobilization-induced neuronal loss in the hippocampus. V. tricolor reduces expression of IL-6 in the hippocampus of immobilized rats.

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HIGHLIGHTS Palliative care in terminally ill patients has only been effective recently in Brazil. Fetuses or neonates unable to curecare received attention in 2017. Brazilian women´s characteristics directly influencing perinatal palliative care.

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HIGHLIGHTS Chondrocytes express PAR-4 in the nucleus and cytoplasm; Vitamin D reduces the pro-apoptotic proteins PAR-4 and caspase-3; PAR-4 and caspase-3 may be potential therapeutic targets for osteoarthritis.

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HIGHLIGHTS Zika virus non-structural proteins are important pharmacological targets. Bixin and derived molecules interact with non-structural proteins. Bixin and ethyl bixin has the potential to interfere with the viral replication mechanism. Bixin and ethyl bixin an indicative of being a promising anti-Zika agent.

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HIGHLIGHTS Essential oil contents of T. spicata, L. X Intermedia, S. macrantha and R. officinalis was determined. The main components of these plants were monoterpenoid T. spicata and S. macrantha showed strong effects against three microorganisms.

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HIGHLIGHTS The platelets serotonin stands out in obtaining wound healing closure. Serotonin receptor gene (5-HTR2A) polymorphisms can cause alterations in the tissue repair. 102T-C polymorphism in the 5-HTR2A gene is associated to alterations in wound healing process.

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HIGHLIGHTS Extracellular vesicles (EV) from human bone marrow were able to reduce airway inflammation in a mouse model. Treatment applied by Intratracheal injection was more effective than systemic administration by caudal vein injection. IT administration of EVs appears to act therapeutically by restoring the basal BAL cell counts and attenuating early lung remodeling.

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HIGHLIGHTS Anticancer activities of ASE and DSE extracts were investigated. Angelica sylvestris have anticancer potential on HT-29 and HeLa cells. Delphinium staphisagria have anticancer potential on A549 and MCF-7 cells. ASE and DSE extracts induce apoptosis on cancer cells.

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HIGHLIGHTS This is the first study of the protective effects of myrtle cream against sulfur mustard-induces chronic skin complication including; itching and burning sensation. Myrtle therapy significantly decreased skin lesion symptoms such as excoriation. Myrtle therapy effectively improved quality of life of the sulfur mustard-exposed veterans.

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HIGHLIGHTS First report of phylogeny and haplotype diversity of Haemonchus contortus isolated from Gaddi (breed) goats of North India. The occurrence of different haplotypes evinced presence of indels at distinct places. There was probable establishment of heterozygosity in putative hybrid H. contortus worms.

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Abstract: Parabens are among the most widely used preservatives in cosmetic formulations. The aim of this study was to investigate the relationship between allergic contact dermatitis (ACD) and the use of parabens in cosmetics. A systematic review was performed with searches in PubMed, Scopus and Science Direct, in addition to a manual search. Interventional or observational studies that assessed the incidence of ACD in individuals using parabens were included. The quality of the articles was assessed and the data were extracted for a qualitative synthesis and single-arm meta-analysis. Fourteen studies (8 longitudinal, 3 cross-sectional, 1 quasi experimental and 2 case reports) were included in the systematic review and had their data extracted. Twelve studies reported ACD after the use of parabens and were included in the single-arm meta-analysis, resulting in an ACD incidence of 0.9%[95%CI: 0.4-2.0%], thus classified as a rare event. This result was related to already sensitized skin in most cases. In addition, the concentration of parabens in the contact test was above that recommended in cosmetics. The incidence of ACD due to parabens is rare, but further studies with control groups and at the usual concentrations of parabens are needed to better evaluate the results.

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Abstract: COVID-19 rapidly spread across the world in an unprecedented outbreak with a massive number of infected and fatalities. The pandemic was heavily discussed and searched on the internet, which generated big amounts of data related to it. This led to the possibility of attempting to forecast coronavirus indicators using the internet data. For this study, Google Trends statistics for 124 selected search terms related to pandemic were used in an attempt to find which keywords had the best Spearman correlations with a lag, as well as a forecasting model. It was found that keywords related to coronavirus testing among some others, such as “I have contracted covid”, had high correlations (≥0.7) with few weeks of lag (≤4 weeks). Besides that, the ARIMAX model using those keywords had promising results in predicting the increase or decrease of epidemiological indicators, although it was not able to predict their exact values. Thus, we found that Google Trends data may be useful for predicting outbreaks of coronavirus a few weeks before they happen, and may be used as an auxiliary tool in monitoring and forecasting the disease in Brazil.

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HIGHLIGHTS Ethanol extract of F. mascrosciadia significantly inhibits collagenase and elastase. Ethanol extract of F. syriaca significantly inhibits collagenase and elastase. Other studied Ferulago species do not show activity on collagenase and elastase enzymes.

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HIGHLIGHTS A field synchronization study. Solution suggestions for the dairy industry. Progesterone different uses. High pregnancy result was obtained.

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HIGHLIGHTS Oxidative stress is considered as a major factor that accelerates the aging process. D-Galactose impairs ambulation, rearing, leaning and grooming responses in mice. L. brevis MG000874 can improve cognitive responses and levels of antioxidants. L. brevis MG000874 can be further confirmed as anti-aging and antioxidant agent. It is recommended to include L. brevis MG000874 in the list of probiotics.

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HIGHLIGHTS E. rutaecarpa acupoint sticking therapy can improve insomnia. Significantly upregulated 5-HT1A mRNA expression and downregulated 5-HT2A mRNA expression.

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HIGHLIGHTS Highly efficient regeneration protocols are reported for Tanacetum parthenium. The highest regeneration was obtained in leaf explants on 0.2 BAP and 0.02 NAA (mg L-1). The protocols are fast and reliable, suitable for rapid propagation of Feverfew. GUS reporter gene was transiently transformed to leaf tissue using biolistic method.

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HIGHLIGHTS Bee pollen reduces oxidative damage and thus it can protect S. cerevisiae against to ROS. Bee pollen induces total protein synthesis. Bee pollen induces S. cerevisiae cell development and it reduces MDA levels and it increases

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HIGHLIGHTS MALDI-TOF is a feasible technique and presents a low cost of reagents. It can be used for the reliable differentiation of B. cenocepacia from other Bcc. Molecular techniques require a highly qualified workforce and demand time. MALDI-TOF identified all specimens at genus level and 96.2% to species level.

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HIGHLIGHTS Hydroalcoholic extract of Phyllanthus niruri (HE-Pn) demonstrates anti-Candida activity. HE-Pn reduces the germ-tube formation and adhesion of Candida albicans. HE-Pn causes cell wall detachment, cytoplasmic granulation, vacuolation and chromatin condensation. HE-Pn shows no toxicity on human keratinocyte cell line.

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HIGHLIGHTS Aerobic vaginitis (AV) is a least explored disease in Pakistan. AV is the predominant cause of vaginitis followed by bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) and trichomonas vaginitis (TV). AV co-occurs significantly in higher frequency with BV and VVC as compared to TV. Patients with history of miscarriage are more prone to AV and BV. Unawareness and low socioeconomic conditions predispose women to TV.

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HIGHLIGHTS The extracellular polysaccharide (EPS) from Enterococcus faecium M20 was characterized. The degradation of polysaccharide was in three steps and it was thermally stable. SAXS data showed that the bacterial EPS possessed the lamellar structure. The investigation of structure of its EPS may be extremely important to find a specific way for treatment of its infection.

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HIGHLIGHTS The expression of exosomes is higher in cancer environment. Exosomes effects T cells proliferation. The expression of CD4-IFNγ and CD8-IFNγ are deregulated by lung cancer exosomes.

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HIGHLIGHTS Mutational analysis of antibiotic resistant genes of E. coli in UTI Patients. These genes were detected by PCR and sequenced using NGS. E. coli isolates were positive for GyrA gene, GyrB gene, tetB and tetR gene. The novel mutation was detected in gyrB gene at codon554.

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HIGHLIGHTS Cloths and sponges are common contaminating utensils in a Food and Nutrition Unit Disinfection methods such as boiling and hypochlorite are efficient Pathogenic microorganisms adhere to the surface of cleaning cloths and sponges

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HIGHLIGHTS Tissue biodistribution of intravenously administered trivalent chromium. Blood clearance rates of intravenously administered trivalent chromium. Faster systemic blood clearance is through renal excretion. Understanding of the above parameters is relevant for its diagnostic applications.

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HIGHLIGHTS Melanoma is a cancer with poor prognosis, and metastasis. Curcumin is a compound with many beneficial effects regarding prevention and adjuvant treatment of cancer Vinblastine and curcumin greatly promoted production of ROS in melanoma cells Curcumin disrupted adenosine formation cascade, reducing imunosupression at tumoral site.

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HIGHLIGHTS Exploring the role of TGFβ and its associate genes in the pathogenetic mechanism of EMT in renal fibrosis. Possible immunohistochemical markers (Pancytokeratin, SMA and Vimentin) to identify the process of EMT. Availability of various EMT related anti-fibrotic therapy with emphasis on stem cell therapy.

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HIGHLIGHTS T2DM is increasing rapidly in the world and this brings a constant search for drugs. Compound VII showed the strongest inhibition on α-amylase activity with low IC50 value. Compound VII, amylase inhibition activity was found to be strong on AR42J cells. Compound VII may play role an alternative and non-cytotoxic α-amylase inhibitor for T2DM.

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HIGHLIGHTS A fuzzy approach represents the COVID-19 dynamics under the effect of vaccination in Brazil. The infected population and the vaccination rate are considered as input variables. The effect of population-wide vaccination is modeled and analyzed. The level of infestation tends to decrease as the number of people vaccinated increases.

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HIGHLIGHTS Permeable cryoprotectants and dextran evaluated in broiler breeder semen. Permeable cryoprotectants produced post-thaw fertility in PB-2 breeder. Low fertility by ethylene glycol or dextran with dimethylacetamide in CB.

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HIGHLIGHTS The effective EPS concentration was determined by xCELLigence analysis method. EPS was able to accelarate ostegenic differentiation. Cellular collagen was increased in the EPS gropus. EPS reduced the calcium granules that occurs due to long term cultivation.

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HIGHLIGHTS It is the first time to compare mushroom tyrosinase model, B16 mouse melanoma cell model and zebrafish model. A high-throughput method for the quantification of melanin in zebrafish skin based on the Phyton for the first time.

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HIGHLIGHTS Rheumatoid arthritis (RA) is a common autoimmune chronic inflammatory joint disease Specialized pharmaceutical services provide access to high-cost antirheumatic drugs Disease-modifying antirheumatic drugs (DMARDs) are widely used in the RA treatment Biological DMARDs treatment exhibit a good efficacy but with a high cost

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HIGHLIGHTS Silsesquioxane 3-n-propylpyridinium chloride (SiPy+Cl-) was synthesized. Copper functionalization of SiPy+Cl- was performed to obtain Cu-SiPy+Cl-. Antimicrobial and cytotoxic effects of SiPy+Cl- and Cu-SiPy+Cl- were demonstrated. Cu-SiPy+Cl- shows a promising use in oral care products.

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HIGHLIGHTS A HCC-associated competing endogenous RNAs network, FAM224A/hsa-mir-139/RAD54B, was established in this study. FAM224A/hsa-mir-139/RAD54B played an important role on HCC progression and metastasis. We revealed that FAM224A may be an important prognostic factor and treatment target for HCC.

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HIGHLIGHTS The pectin-like polysaccharide was isolated from the Caesalpinia pulcherrima leaves. Showed promising results of antioxidant activity in in vitro assays. The polysaccharide is non-toxic, stimulates cell activation and cytokine production in in vitro. Promising therapeutic agent.

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HIGHLIGHTS The effects of different extraction methods on bioactive compounds of propolis. The highest antioxidant activity was obtained by ultrasound application. The highest phenols and esters were obtained by microwave-assisted method.

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HIGHLIGHTS First report of endophytic bacteria isolated from weed (Lactuca indica) Endophytic bacteria, L115 strain, inhibit significantly the development of Alternaria alternata. L115 strain promotes the growth parameters of multiple plants compared to the control.

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HIGHLIGHTS In this study, three safflower cultivar (Balcı, Dinçer, Remzibey) were used. Four different concentrations of boric acid (0, 5, 10, 15 mM) were applied to the plants. SOD, CAT, APX, GR activities of plant samples were investigated by spectrophotometric method and expression levels of these enzymes by RT-qPCR. The Remzibey variety was found to have the lowest antioxidant capacity to deal with oxidative stress compared to other varieties.

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HIGHLIGHTS L. barbarum promote the increase in catalase enzyme activity in the liver of rats. L. barbarum increase mRNA expression of catalase enzyme in the liver of rats. L. barbarum extract produced a significant oxidation decrease in the liver of rats. L. barbarum extract has a significant amount of bioactive compounds.

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HIGHLIGHTS Climatic conditions influence the physiological mechanisms of species. High irradiance and air temperature reduce photosynthetic performance of species. The highest physiological performance of the species is between 8 am and 9 am.

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HIGHLIGHTS Technological analysis of the production for a virus-based biopesticide. Selection of technological conditions considered to have a significant influence. Scale-up strategy based on geometric and the dynamic similarities. Reproducibility and repeatability assessment of the formulation process.

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HIGHLIGHTS Tradescantia pallida has shown promising antibacterial, antioxidant and anticancer activities. Botanical extract products are environmentally friendly, inexpensive and may reduce losses by discouraging pathogen growth. HE-TP was highly active in in vitro assays against P. digitatum, S. sclerotiorum and R. stolonifer. HE-TP demonstrated cytotoxic activity against different human tumor cell lines. The major compound identified in hexane extract from T. pallida was (E)-4-methoxycynnamic acid (50.2%).

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Abstract: Here we report the current gene impact of the Au family of SINEs in tomato. The genome of Solanum lycopersicum ‘Heinz 1706’ SL3.0 -NCBI annotation release 103- was reference searched and the Au profile was characterized in-depth. Tomato genome comprises ca. 670 Au copies, of entire length-18.5%- or truncated, randomly inserted and eroded, forming three well supported (>80%) super clusters which disperse along the 12 chromosomes mirroring the subtelomeric gene distribution bias of the species. In tomato, the Au clade is largely localized at protein coding genes-69.5% introns, 7.8% 3UTRs, 2.1% 5UTRs, 1.2% CDSs- followed by genomic copies-18.3%-, long non coding RNA genes-1.4%- and pseudogenes-0.8%-. The 419 tomato genes harboring intronic Au are diverse, weakly associated considering biological processes and molecular functions, but include important traits such as stress response, hormone response or phenotype plasticity. Au was found to be transcribed inside circular RNAs derived from 12 genic loci. Exonic Au affect the transcriptional and/or translational profiles of 67 tomato genes, including biological/agronomical important ones, contributing to UTR length and composition, UTR transcript variants, CDS boundary definitions, protein domains and variants. We propose that biased survival of Au in tomato genes is an adaptive feature.

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HIGHLIGHTS Karyological relationships are useful to infer processes of evolution and speciation. This paper reports chromosomal data of 38 taxa. First report (9) and new count (5). Dysploidy, polyploidy, and karyotype asymmetry are important parameters. Dysploidy and polyploidy variations are main factors in karyotype evolution of genus.

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HIGHLIGHTS Bacillus thrungiensis var. israilensis.causes mortality of Culex sp. larvae. Spinosad causes mortality of Culex sp. larvae. Bio-larvicides were an effective controlling tool for mosquitoes in Kahramanmars.

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HIGHLIGHTS Eight species of bacteria and three yeasts were identified in T. angustula products. Bacillus was the main bacteria present in pots of stingless bee honey and pollen. S. meliponinorum was the main yeast found in jataí honey, and Z. bailli in jataí pollen. Symbiotic relationship between microorganisms and honey and pollen pots

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HIGHLIGHTS Human pathogenic fungus Trichophyton tonsurans has a longer survival period Jaipur climatic condition favor the recurrence of keratinophilic and dermatophilic fungi. Unsterilized soil samples are potent source of fungal niche.

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HIGHLIGHTS New parthenocarpic gynoecious cucumber line ‘PBRK-11’ was developed and characterized. Application of silver thiosulphate @ 250 ppm induced maximum number of male flowers per plant, minimum plant mortality percentage and induced male flowers for longer duration. In vitro protocol was standardized to maintain the parthenocarpic gynoecious inbred “PBRK-11”.

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HIGHLIGHTS Extraction and characterization of galactan from different five red species. The biological activities of galactans were correlated to their uronic acid and sulphate content. Galaxaulra rugosa galactan had the highest antioxidant and antiproliferative activity. The extracted galactans can be used to improve the human health.

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HIGHLIGHTS Thymol was identified as the main metabolite in the EOLO. EOLO has antibacterial activity against Gram-negative and Gram-positive bacterial pathogens. The antibacterial effect of EOLO may be associated with the presence of thymol.

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HIGHLIGHTS Classification of virus texture based on pre-trained CNN and ECOC classifier is proposed. Model accuracy improved using Chebyshev moments and the pruned features of Resnet50. The proposed algorithm outperformed in terms of classification accuracy.

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HIGHLIGHTS The maximum production of the pyocyanin was found to occur in MFDM and with shaking. UV-VIS spectroscopy, GC-MS, and FT-IR analyses showed the presence of pyocyanin. Pyocyanin had no cytotoxic impact on L929 cells (except 50-100 μM concentrations). Pyocyanin had an antiproliferative impact on SK-MEL-30 cells. Pyocyanin had in vitro and cellular AChE inhibitory and antioxidant properties. The use of the pyocyanin as a neuroprotective agent or an anticancer agent is advised.

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HIGHLIGHTS The effective approach to advance mosquito surveillance and monitoring program The impacts of diverse environmental conditions for better amalgamation of Aedes aegypti control Risk assessment studies and utilization of these tools for economically important vector control programs and disease prevention activities.

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HIGHLIGHTS Exercise increases plasma albumin, while reducing ALT and creatinine. Rosehip reduces AST, creatinine, urea, cholesterol, and triglyceride. D-galactose increases ALT, AST, ALP, creatinine, urea, cholesterol, and triglyceride. Rosehip adjusts the changes induced by D-galactose on some variables.

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HIGHLIGHTS The microbiological properties of minced chicken changed with the use of rosemary extract. A significant increase in shelf-life and quality was achieved depending on the extract concentration. The use of 1% rosemary extract had a positive effect on the quality parameters. Storage day and rosemary (Rosmarinus officinalis) extract supplementation dependent microbial values in minced chicken meat can be modelled with values close to 1.

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HIGHLIGHTS Low calorie Bitter gourd-Kiwifruit beverage has good antioxidant potential and sensory acceptability. Product optimization showed about 80% reduction in calorie value. Optimized beverage showed good storage stability at ambient conditions for a period of six months.

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HIGHLIGHTS Lactic acid bacteria (LAB) from goat milk exhibited antimicrobial potential LAB with probiotic attributes were identified as Enterococcus faecium Enterococcus spp. showed no hemolysis and mild antibiotic resistance

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HIGHLIGHTS Parasitic diseases transmitted by fish are a global public health problem. The occurrence of parasites in Alaska pollock fish is significant. Control measures are needed to minimize the occurrence of parasites in fish.

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Abstract: Lentinula edodes is the most consumed mushroom in the world, being cultivated mainly on waste coming from the forest industry. During shiitake cultivation, incubation is essential and is usually longer than in other edible mushrooms. This stage includes “browning”, which is a process induced by exposure to a photoperiod and although it is believed to bring certain advantages to shiitake cultivation, it has not been widely studied. In this work, we evaluated how the incubation time, the use of different strains and the induction of browning affect the proximate composition, biological efficiency and other yield parameters of L. edodes. In order to do that, three experiments were carried out with three different strains, three different incubation times and the effect of induction or non-induction of browning. As results we found that the proximate composition did not vary with respect to the different incubation times or from the induction of browning, although differences were found according to the strain. On the other hand, the biological efficiency was affected by the incubation time and the strain used, but not by the induction of browning.

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HIGHLIGHTS Two novel yeast strains were identified by sequencing for rice wine production. Rice wine (low alcohol by volume) was prepared from local raw materials of Nepal. Yeast and mould isolated from Parbat murcha showed potential fermentative characters.

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HIGHLIGHTS The use of Spirulina platensis increased the growth of cashew seedlings. S. platensis increased the accumulation of plant biomass of cashew seedlings. S. platensis can be used as a biostimulant for plant production.

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HIGHLIGHTS The flour of the sweet passion fruit peel has a high dietary fiber content. Adding sweet passion fruit peel flour increases the fiber content in cookies. Cookies enriched with passion fruit peel flour have good sensory acceptability. Full use of sweet passion fruit reduces waste and improves nutritional value.

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HIGHLIGHTS Effects of the addition of flaxseed powder (FSP) were examined on yoghurts. The FSP improved syneresis and water holding capacity of yoghurts. The FSP enhanced viscosity and rheological properties of yoghurts. Microbiological properties of FSP added yoghurts was coherent with legal. The sensory properties of FSP added yogurts were acceptable except for one containing 1%.

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HIGHLIGHTS The study shows the S. aureus counts of the 100 frozen cheese bread samples analyzed. 27 samples (27.0%) had S. aureus counts greater than 5.0 × 103 CFU/g. None of the 62 S. aureus strains isolated carried the genes sea, seb, sec, or sed. Heat treatment at 180 °C for 35 minutes was not sufficient to inactivate SEA.

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HIGHLIGHTS Microwave drying lead to improve the drying characteristics of Hawthorn slices. Page model was found as the best described the microwave drying data. Microwave drying at 360 W can be applied as an effective technology for drying of hawthorn slices.

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HIGHLIGHTS Chitosan and clove essential oil to improve the characteristics of strawberries. Different treatments were applied in minimally processed strawberries. The applied coatings were efficient to increase the preservation time of strawberries. T3 treatment presented better results in retarding the growth of molds and yeasts.

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HIGHLIGHTS 46.29% of the samples were unacceptable according to the maximum limit of E. coli. 87.03% of the samples were unacceptable according to the maximum limit of S. aureus. 38.90% of the samples were unacceptable according to the presence of Salmonella spp. The kind of spice which had the best microbiological quality was thyme.

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HIGHLIGHTS The term ‘yoghurt’ relates to the Turkish word ‘Jughurt’ and to yogurmark ‘to knead’ and yogum ‘dense’ or ‘thick.’ The method of manufacture for different yogurt products is nevertheless quite like yoghurt production. The difference is in the use of specific cultures, incorporation of additives, curd treatment, and method of packaging. Consumers may seek for low-fat dairy products, which may suffer from a lack of sensory quality The incorporation of basil seed gum into yogurt is one of the conceivable ways to promote health benefits.

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HIGHLIGHTS The slices of different thickness in experiment is 0.2mm, 0.3mm, 0.4mm and 0.5mm using electric and wooden slicer. The suitability of temperature for acceptance of chip colour is best at 170 C and 180 °C except at 190 °C. Reduction of oil absorption is maximum of slice thickness of 0.5mm. After processing, reducing sugars content is reduced by 77.9 % and 81.1 % at 180°C with 0.2mm thickness in variety Kufri Chipsona-1 and Kufri Chipsona-3. Processed chips retained more phenols than raw potato.

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HIGHLIGHTS Pesticide residues in foods can result in extremely harmful impacts on human health. Pesticide residues its have been identified in tomatoes. There was no of chronic dietary exposure risk to pesticides through of tomatoes. The tomatoes were safe for human consumption.

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HIGHLIGHTS Automatic tool is developed for diagnosis of pneumonia. Boosting techniques are used in terms of their speed and ease of use in real time applications. The best result in terms of simulation duration and accuracy is Catboost with 0.7 seconds running time and 83% accuracy. The results obtained from the model become more understandable using tool. A bridge is designed between the model and the user by the automatic tool. By using this tool, a diagnosis can be done quickly and accurately without any expert. So, treatment can be started quickly.

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HIGHLIGHTS Evaluation of the impacts of electric vehicles penetration on distribution grids. Power flow simulations on GridLab-D software considering the distribution grid with electric vehicles charging stations and a carport. Analysis of the real distribution grid of Fernando de Noronha Island.

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HIGHLIGHTS A new method of extracting the feature points in superpixels is proposed to compute the candidate disparities using non-local cost aggregation. A novel two-stage optimization framework for superpixel proposals by first getting the labels of feature points quickly and then consists the candidate label sets for updating the labels of pixels within the corresponding superpixel instead of assigning a label randomly to those pixels. The weight combination of intensity, gradient and binary image is designed for constructing an optimal minimum spanning tree to compute the aggregated matching cost.

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HIGHLIGHTS This work introduces the Gudermannian function as a sigmoid growth model. Hyperbolic and trigonometric identities provide several parameterizations of this model. The Gudermannian growth model can be a good alternative to the classical sigmoid models.

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HIGHLIGHTS Local Atmospheric Electrical Circuit – LAEC with line transmission The waveform in atmospheric coupling (transmission line - LT) is out of phase by 10.34. A voltage drop difference of 0.27% is observed in relation to the atmospheric coupling. Signal with peaks at 100kV induced approximately 0.66% of the LT voltage (375kV).

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HIGHLIGHTS An approach using AI techniques is proposed to evaluate real-time versus dispatch on a microgrid. Artificial Neural Network is used to predict load and renewable generation operation point on a microgrid. A novel approach with three-dimension analysis for deviation between day-ahead dispatch and real-time is presented. Adjustments in operation point are performed using fuzzy logic or MILP according to deviation between dispatch and real-time operation points.

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Abstract: The aim of this study is to evaluate the parameters such as pH, dissolved oxygen, temperature, conductivity, salinity, biological oxygen demand (BOD), total suspended solid, ammonia, chlorophyll-a and heavy metals affecting total coliform values in seawater using Artificial Neural Network (ANN) modelling at the Eastern Black Sea coast of Turkey. The results obtained from ANN model were compared with actual total coliform values. The samples were taken from the different points selected along the deep sea discharge systems starting from the diffuser end of three domestic deep sea discharge systems at Turkey's Eastern Black Sea coast. ANN model was developed for estimating the relationship between total coliform and other parameters. The parameters measured in seawater samples were analyzed by using the ANN model for prediction of coliform values. The results showed that neural network model is capable of estimating the sea pollution with a reasonable accuracy.

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ABSTRACT: Identification and classification of intracardiac masses in echocardiogram is one of the significant processes in the diagnosis of cardiovascular disease. A robust back propagation neural network (RBPNN) technique is used to conquer every single conventional-issue utilizing the echocardiogram image analysis for this work, which consists of four phases such as noise removal, automatic segmentation, feature extraction, and intracardiac masses classification. Initially, the noise is diminished from the echocardiogram images utilizing the adaptive vector median filter (AVMF). Then, linear iterative vessel segmentation (LIVS) is applied for automatic segmentation of the masses followed by the extraction of texture features using the multiscale local binary pattern (MS-LBP) approach. Finally, RBPNN is employed to classify the heart mass from the images of echocardiogram with the layered kernel for the system combination. Extensive simulation results obtained using proposed AVMF-MS-LBP based RBPNN approach disclosed the superiority over existing intracardiac mass detection and classification approaches in terms of accuracy of 98.85%.

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HIGHLIGHTS Business model for electrical energy distribution utilities. Distributed photovoltaic generation impacts in current Brazilian tariffs. Binomial tariffs for Brazilian costumers at low voltage.

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HIGHLIGHTS Optimization of distribution grid operation with distributed energy resources. Modeling and simulation of an Optimum Power Flow solved with Interior Points Method implemented in Python language. Robustness even with the implementation in a 90 bus test distribution feeder with multiple distributed energy resources simultaneously.

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HIGHLIGHTS SPC is obtained by solid-liquid extraction process with hydroalcoholic solvent. Box-Behnken was applied to evaluate the effect of operational parameters. Soluble carbohydrate extraction from DSM is limited by intraparticle diffusion. Diffusion coefficient of stachyose, raffinose, sucrose, and glucose was estimated.

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HIGHLIGHTS Proposed a hybrid feature ranking algorithm named VIGAREA The proposed feature ranking algorithm gives importance to the individual feature as well as interaction between the features. The proposed VIGAREA can combine any number and type of feature selection methods along with information gain ratio

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HIGHLIGHTS BP term related to neuron differentiation was the most significant GO terms. Regulation of actin cytoskeleton may play an important role in OA progression. GNAO1 and POU3F4 may be biomarkers of OA.

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HIGHLIGHTS Metronidazole is selected for this study because it is a poorly compressed drug. This study is based on the comparison of various physicochemical parameters of round and oblong shape tablets. Different statistical results showed that round shape is more stable form for poorly compressed drugs like metronidazole.

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HIGHLIGHTS The use of 3D models in medicine brings several advantages in the medical field. AM is useful for the patient's understanding of the disease. AM is a fast and low-cost option to produce patient-specific AI models that can be used for surgical planning.

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HIGHLIGHTS Proposed Hybrid Word Embedding (HWE) models for Efficient Text classification. Data Sparsity issue is reduced using WordNet repository along with proposed model. Optimal model is derived based on the Performance evaluation on the model.

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HIGHLIGHTS Mapping of the Robotic Process Automation (RPA). Recent advances and new possibilities of RPA. RPA platforms available on the market.

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HIGHLIGHTS An alternative method to sub-daily rainfall data for locals with scarce data. Intensity-duration-frequency curves were fitted by observed and disaggregation data. Assessment disaggregation coefficients for intensity-duration-frequency curves. Disaggregated sub-daily rainfall data adequately reproduced the IDF curves.

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HIGHLIGHTS BAT algorithm is presented to minimize makespan as objective for the permutation flowshop scheduling problem by modifying the process parameter. In order to improve the initial quality & diversity, an NEH heuristics based constructive approach is given an initial solution.

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HIGHLIGHTS Fake transactions are inserted into database to hide item frequency. The input binary bits are grouped into N sets with length as four for encryption. Each item in a data set is encoded with A,C,G,T DNA codons. Encrypted Association rules are built for frequent items in a transaction.

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HIGHLIGHTS Influence of Fly ash and Coir Fibre in mechanical performance of Polymer composite Polymers exhibits varying performance in tensile and flexural loading A threshold fly ash proportion has been limited to 5- 10%. Increasing fibre length shows improvement in strength whereas short fibre are good enough for modulus.

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HIGHLIGHTS A hybrid approach using time frequency analysis and deep learning for risk stratification of epileptic seizure is proposed. An extensive comparative study of various machine learning and feature selection techniques is conducted. Implemented andevaluatedthedeep learning based long short-term memory networks.

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HIGHLIGHTS Analyzation of social-reforms. Cohesiveness of Hate and Harassment. Comparison of Reform Movements. Implications to Policy.

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HIGHLIGHTS The permissioned blockchain is used for resource allocation and monitoring. To reduce storage size, partial data is stored in the onchain blocks instead of entire data. The EU’s based Fixed and variable size resource allocation techniques are proposed.

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HIGHLIGHTS An AC linear optimal power flow model for unbalanced ZIP loads. Model includes voltage regulators, distributed generation, and mutual impedance. Results show deviations lower than 0.6% for voltage magnitude compared to a non-linear model. Results show deviations lower than 3% for voltage angle compared to a non-linear model.

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HIGHLIGHTS Orally disintegrating films were prepared by solvent casting using HPMC polymer. Films were prepared by 32 factorial designs for oral delivery of captopril. Mechanical, optical, and dissolution properties were evaluated. The experimental design allowed to optimize the formulation.

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HIGHLIGHTS This research aimed to explore low-cost light sensors for agriculture. TSL2561, BH1750, TEMT6000, light sensors have been used. Low-cost light sensors can be used for a range of applications in agriculture. The light calculation values of low-cost light sensors were statistically compared. Calibration results were also analyzed, so the reliability of low-cost light sensors was calculated.

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HIGHLIGHTS Global warming manifests itself as an irregularity in rainfall. Correct measures should be taken to determine the rainfall irregularities. More efficient use of water resources can only be achieved through data analysis. In this research, a new mobile pluviometer was developed. The rainfall intensity was best determined by Random Forest algorithm.

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HIGHLIGHTS A self-sufficient system is presented Energy is generated by photovoltaic panels Rainwater is captured and treated with ultraviolet lighting. This water is used in toilets, pulping the use of drinking water

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HIGHLIGHTS Advancement of analyzes using the wavelet technique applied to genome data. Analyze the entire genome, that is, there is no loss of information. It represents a more detailed technique in which energy (variance) is used.

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HIGHLIGHTS Investigation of pathogenic fungi sequences from the metagenomic data of Cerrado soils. The native vegetation samples show higher relative abundance of pathogenic fungi. Identification of 41 pathogenic fungal species associated with human and animal infections.

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HIGHLIGHTS The contamination of blanks by airborne fibers in the lab was investigated. Microfibers could be overestimated in fish’s gastrointestinal tract and surface water. We tested and approved an Airborne Contamination Control Protocol (ACC Protocol).

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HIGHLIGHTS Solar saltwork production does not affect water quality. Salinity is not affected by salt production. The ions present in the estuary are not affected by salt production. The estuary is oligotrophic and is not affected by salt production.

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HIGHLIGHTS Hierarchical cluster analysis was efficient in determining climatic areas. The elbow method for the optimal number of clusters was the most suitable. Notch boxplot analysis and comparing tests can help in the number of clusters. The clusters formed were correlated with geographical and climatic variables. Meteorological systems and topography assist in the discrimination of clusters.

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HIGHLIGHTS Oil palm empty fruit bunch is sufficient to be used as reinforcement on the biopot production. Application of sodium alginate deliver a positive effect on the biopot’s mechanical properties. Properties of the developed biopot indicate the possibility to substitute the plastic pot use.

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HIGHLIGHTS The most used model types and independent variables to forecasting Brazilian CO2 emissions can be obtained by literature review. Gray models and artificial neural networks are the most promising modeling methods. Economic growth and energy consumption are the main independent variables to forecasting Brazilian CO2 emissions.

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HIGHLIGHTS Brazilian scientific production on snake peptides has grown over the years. São Paulo, is the most representative state in Brazil in research. The main periodical where researches were published, is the Toxicon journal. Collaboration is observed between institutions in Brazil and other countries.

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HIGHLIGHTS Most Brazilian entomology has focused on the Atlantic Forest biome. Research on the Amazon and Pantanal biomes should be increased given their biodiversity. The Hymenoptera is the most studied taxon in Brazil for conservation. Aquatic insects are widely used in official monitoring and conservation programs. Insect recovery programs should provide effective conservation.

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HIGHLIGHTS Starch is promising biopolymer to be used as a biodegradable natural source. The combination of starch with nanocellulose can provide new applications. Glycerol is an additive widely used in the production of biodegradable packaging. Biodegradable films are effective to extend the shelf life of fresh vegetables.