Epileptic Seizure Detection Using Deep Learning Based Long Short-Term Memory Networks and Time-Frequency Analysis: a Comparative Investigation in Machine Learning Paradigm

HIGHLIGHTS

• A hybrid approach using time frequency analysis and deep learning for risk stratification of epileptic seizure is proposed.

• An extensive comparative study of various machine learning and feature selection techniques is conducted.

• Implemented andevaluatedthedeep learning based long short-term memory networks.

Abstract

Epilepsy is a noncontagious brain abnormality, which causes electrical distraction and strains the neural system. Generally, epilepsy is treated and diagnosed through continuous examination and interpretation of the electroencephalography (EEG) signals. This is a very time-consuming and tedious job. Further, it is subjected to observational errors and observer variability. Hence, the development of an efficient automatic alarm system to recognize epileptic seizure signals is of important concern. The objectives of the present study are to investigate deep learning based long short term memory (LSTM) networks for the classification of epileptic EEG signals using time-frequency analysis. Additionally, a comparative investigation is carried out to evaluate the various state-of-the-art feature selection and classification models for automatic classification of EEG signals for Epilepsy detection. Features based on statistics, entropy, and fractal were extracted from both the time domain and frequency domain. The extracted features were supplied to LSTM networks and traditional machine learning models for epileptic EEG classification. High classification accuracy of 100% (under hold out and 10-fold protocol) and 99.80% (under 10-fold protocol) is achieved by the proposed LSTM strategy followed by the Back Propagation Artificial Neural network (BPANN) which achieves 99.6% classification accuracy when all the 150 EEG biomarkers were used as input to the classifier under 10-fold cross-validation technique. Further, when the top 30 most relevant features selected by different feature selection techniques are used for classification, the proposed approach achieves similar performance followed by BPANN which reports 99.4% classification accuracy when combined with the Relief F feature selection technique.

Keywords:
EEG; epileptic seizure; risk stratification; deep learning; long term short memory networks; machine learning.