Response to the article “Pharmacotherapy assessment in chronic kidney disease: validation of the pair instrument for use in Brazil”

We appreciate the careful reading of our study and the comments received, as they are relevant, demonstrate the importance of the multidisciplinary debate, and raise fundamental points in this field of research.

The article “Pharmacotherapy assessment in chronic kidney disease: validation of the pair instrument for use in Brazil”¹, authored by Alessandra Batista Marquito, Hélady Sanders Pinheiro, Natália Maria da Silva Fernandes, and Rogério Baumgratz de Paula, aimed to validate the PAIR (Pharmacotherapy Assessment in Chronic Renal Disease) instrument for use in Brazilian Portuguese. Jean-François Desrochers and collaborators, from the University of Montreal, Canada², originally developed this instrument.

In the present study, in line with the regulations for the validation of foreign language instruments^3,4, we sought to remain strictly consistent with the original instrument⁵, which is why fundamental issues such as those mentioned in the letter to the editor were not included. The inclusion of new drug-related problems (DRPs) to the list of criteria in the PAIR would imply the use of a specific methodological proposal, which would cause a change to the original proposal of the PAIR creators.

In fact, the high prevalence of depression, anxiety and other disorders such as sleep disorders, leads to high consumption of psychotropic drugs that, in association with chronic kidney disease, can favor the occurrence of DRPs. However, as previously mentioned, due to the validation methodology, we had to remain consistent with the original instrument.

Thus, we hope to have clarified the questions posted in the editor’s letter, at the same time that we are grateful for the comments of our colleagues, comments that certainly open perspectives for new studies involving the evaluation of pharmacotherapy, in particular of drugs with action on the central nervous system in patients with chronic kidney disease.

REFERÊNCIAS

• ¹
  Marquito AB, Pinheiro HS, Fernandes NMS, Paula RB. Avaliação da farmacoterapia na doença renal crônica: validação do instrumento PAIR para uso no Brasil. Braz. J. Nephrol. 2020; Ahead of Print. https://www.scielo.br/pdf/jbn/2020nahead/pt_2175-8239-jbn-2019-0205.pdf
  » https://www.scielo.br/pdf/jbn/2020nahead/pt_2175-8239-jbn-2019-0205.pdf
• ²
  Desrochers JF, Lemieux JP, Morin-Bélanger C, Paradis FSM, Lord A, Bell R, et al. Development and validation of the PAIR (pharmacotherapy assessment in chronic renal disease) criteria to assess medication safety and use issues in patients with CKD. Am J Kidney Dis. 2011 Out;58(4):527-35.
• ³
  Guillemin F, Bombardier C, Beaton D. Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. J Clin Epidemiol. 1993 Dez;46(12):1417-32.
• ⁴
  Beaton DE, Bombardier C, Guillemin F, Ferraz MB. Recommendations for the cross-cultural adaptation of the DASH & QuickDASH outcome measures. New York: Institute for Work & Health; 2002; [acesso em 2020 Jun 01]. Disponível em: http://www.dash.iwh.on.ca
  » http://www.dash.iwh.on.ca
• ⁵
  Marquito AB, Pinheiro HS, Paula RB. Adaptação transcultural do instrumento PAIR: pharmacotherapy assessment in chronic renal disease para aplicação no Brasil. Ciênc Saúde Coletiva [Internet]. 2020 Out; [citado 2019 Mai 18]; 25(10):4021-32. Disponível em: http://www.cienciaesaudecoletiva.com.br/artigos/adaptacao-transcultural-do-instrumento-pair-pharmacotherapy-assessment-in-chronic-renal-disease-para-aplicacao-no-brasil/17143
  » http://www.cienciaesaudecoletiva.com.br/artigos/adaptacao-transcultural-do-instrumento-pair-pharmacotherapy-assessment-in-chronic-renal-disease-para-aplicacao-no-brasil/17143

Publication Dates

• Publication in this collection
  23 Nov 2020
• Date of issue
  Oct-Dec 2020

History

• Received
  30 July 2020
• Accepted
  26 Aug 2020