Characteristics of health professionals affected by Covid-19: an integrative literature review

Collaborators

Rocha RPS (0000-0002-2295-5321)^* * Orcid (Open Researcher and Contributor ID). , Oliveira JLC (0000-0002-1822-2360)^* * Orcid (Open Researcher and Contributor ID). and Carvalho ARS (0000-0002-2300-5096)^* * Orcid (Open Researcher and Contributor ID). contributed to the planning, conception, analysis, interpretation of the data, writing, relevant critical review and final approval of the version to be published. Silva GKT (0000-0001-7988-7553)^* * Orcid (Open Researcher and Contributor ID). contributed to the collection, analysis and interpretation of data and final approval of the version to be published. Matos BAB (0000-0003-1987-9687)^* * Orcid (Open Researcher and Contributor ID). , Mufato LF (0000-0002-8693-5637)^* * Orcid (Open Researcher and Contributor ID). and Ribeiro AC (0000-0003-1607-3215)^* * Orcid (Open Researcher and Contributor ID). contributed to the relevant critical review of the intellectual content, final approval of the version to be published.

Conflict of interests: non-existent Financial support: non-existent

Authors/Year	Study Country	Study Design	Health professional sample
Alma T et al., 2020¹³13 Alma T, Bradley J, Bousema T, et al. Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands March 2020. Euro Surveill. 2020; (16):2000508.	Netherlands	Cohort	90
Chen et al., 2020¹⁴14 Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020; 395(10223):507-13.	China	Exploratory/Transverse	15
Eric J et al., 2020¹⁵15 Eric J, Chow MD, Noah G, et al. Symptom Screening at Illness Onset of Health Care Personnel With SARS-CoV-2 Infection in King County, Washington. JAMA. 2020; 323(20):2087-2089.	USA	Cohort	48
Guan et al., 2020¹⁶16 Guan W, Ni Z, Hu Y, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382(18):1708-20.	China	Cohort	38
Guo X et al., 2020¹⁷17 Guo X, Wang J, Hu D, et al. Survey of COVID-19 Disease Among Orthopaedic Surgeons in Wuhan, People’s Republic of China. J Bone Joint Surg Am. 2020; 102(10):847-854.	China	Exploratory/Transverse	24
Heinzerling et al., 2020¹⁸18 Heinzerling A. Transmission of COVID-19 to Health Care Personnel During Exposures to a Hospitalized Patient — Solano County, California, February 2020. MMWR. 2020; 69(15):472-476.	USA	Cohort	121
Jiaojiao C et al., 2020¹⁹19 Jiaojiao C, Yang N, Wei Y, et al. Clinical Characteristics of 54 Medical Staff With COVID-19: A Retrospective Study in a Single Center in Wuhan, China. J Med Virol. 2020; 92(7):807-813.	China	Cohort	54
Keeley et al., 2020²⁰20 Keeley AJ, Evans C, Colton H, et al. Roll-out of SARS-CoV-2 testing for healthcare workers at a large NHS Foundation Trust in the United Kingdom, March 2020. Euro Surveill. 2020; 25(14):2000433.	United Kingdom	Exploratory/Transverse	52
Li Q et al., 2020²¹21 Li Q, Guan X, Wu P, et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. 2020; 382(13):1199-207.	China	Exploratory/Transverse	15
Liu, M et al., 2020²²22 Liu M, He P, Liu HG, et al. Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia. ResearchGate. 2020; 43(3):209-214.	China	Exploratory/Transverse	30
McMichael et al., 2020²³23 McMichael TM, Currie DW, Clark S, et al. Epidemiology of Covid-19 in a Long-Term Care Facility in King County Washington. N Engl J Med. 2020; 382(21):2005-11.	USA	Exploratory/Transverse	151
Qi Z et al., 2020²⁴24 Qi Z, Yin YL, Qiong L, et al. Spinal Anaesthesia for Patients With Coronavirus Disease 2019 and Possible Transmission Rates in Anaesthetists: Retrospective, Single-Centre, Observational Cohort Study. BJA. 2020; 124(6):670-675.	China	Cohort	44
Sun H et al., 2020²⁵25 Sun H, Lu M, Chen S, et al. Nosocomial SARS-CoV-2 infection among nurses in Wuhan at a single centre. J Infect. 2020; 80(6):e41-2.	China	Exploratory/Transverse	32
Wang F et al., 2020²⁶26 Wang FD, Chen YY, Lee YM, et al. Positive Rate of Serum SARS-CoV Immunoglobulin G Antibody Among Healthcare Workers. Scand J Infect Dis. 2007; 39(92):152-156.	China	Cohort	6
Reusken et al., 2020²⁷27 Reusken CB, Buiting A, Bleeker-Rovers C, et al. Rapid assessment of regional SARS-CoV-2 community transmission through a convenience sample of healthcare workers, the Netherlands, March 2020. Euro Surveill. 2020; 25(12).	Netherlands	Exploratory/Transverse	85
Ying-Hui et al., 2020²⁸28 Ying-Hui J, Huang Q, Wang YY, et al. Perceived Infection Transmission Routes, Infection Control Practices, Psychosocial Changes, and Management of COVID-19 Infected Healthcare Workers in a Tertiary Acute Care Hospital in Wuhan: A Cross-Sectional Survey. Mil Med Res. 2020; 11:7(1):24.	China	Exploratory/Transverse	103
Yu X et al., 2020²⁹29 Yu X, Sun X, Cui P, et al. Epidemiological and clinical characteristics of 333 confirmed cases with coronavirus disease 2019 in Shanghai, China. Transbound Emerg Dis. 2020; 67(4):697-1707.	China	Exploratory/Transverse	4
Escribese M et al., 2020³⁰30 Escribese MM, Nistal-Villan E, Fernandez P, et al. Cross-sectional pilot study exploring the feasibility of a rapid SARS-CoV-2 immunization test in health and nonhealthcare workers. Allergy. 2020; 76(3):896-899.	Spain	Exploratory/Transverse	50
Marra M et al., 2021³¹31 Marra A, Generali D, Zagami P, et al. Seroconversion in patients with cancer and oncology health care workers infected by SARS-CoV-2. Ann Oncol. 2021; 32(1):113-19.	Italy	Cohort	105
Ying- Hui J et al., 2020³²32 Jin YH, Huang Q, Wang YY, et al. Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey. Mil Med Res. 2020; 7(1):24.	China	Exploratory/Transverse	105
Fwoloshi S et al., 2020³³33 Fwoloshi S, Hines JZ, Barradas DT, et al. Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) among Health Care Workers—Zambia, July 2020. Clin Infect Dis. 2021 [acesso em 2021 jun 24]; ciab273. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083617/pdf/ciab273.pdf https://www.ncbi.nlm.nih.gov/pmc/article...	Africa	Exploratory/Transverse	660
Lombardi A et al., 2020³⁴34 Lombardi A, Consonni D, Carugno M, et al. Characteristics of 1573 healthcare workers who underwent nasopharyngeal swab testing for SARS-CoV-2 in Milan, Lombardy, Italy. Clin Microbiol Infect. 2020; 26:1413:e9e1413.e13.	Italy	NS	139
Lahner E et al., 2020³⁵35 Lahner E, Dilaghi E, Prestigiacomo C, et al. Prevalence of Sars-Cov-2 infection in health workers (HWs) and diagnostic test performance: the experience of a teaching hospital in central Italy. Int J Environ Res Public Health. 2020; 17(12):4417.	Italy	Exploratory/Transverse	58
Al-Kuwari MG et al., 2021³⁶36 Al-Kuwari MG, AbdulMalik MA, Al-Nuaimi AA, et al. Epidemiology Characteristics of COVID-19 Infection Amongst Primary Health Care Workers in Qatar: March-October 2020. Front Public Health. 2021; (9):1-6.	West Asia	Exploratory/Transverse	1.199
Liu J et al., 2021³⁷37 Liu J, Ouyang L, Yang D, et al. Epidemiological, clinical, radiological characteristics and outcomes of medical staff with COVID-19 in Wuhan, China: Analysis of 101 cases. Int J Med Sci. 2021; 18(6):1492-1501.	China	Cohort	101
Abdelmoniem R et al., 2020³⁸38 Abdelmoniem R, Fouad R, Shawky S, et al. SARS-CoV-2 infection among asymptomatic healthcare workers of the emergency department in a tertiary care facility. J Clin Virol. 2021; (134):104710.	Egypt	NS	29
Rodriguez A et al., 2021³⁹39 Rodriguez A, Arrizabalaga-Asenjo M, Fernandez-Baca V. Seroprevalence of SARS-CoV-2 antibody among healthcare workers in a university hospital in Mallorca, Spain, during the first wave of the COVID-19 pandemic Adrian. Int J Infect Dis. 2021; (105):482-486.	Spain	NS	61
Alkurt G et al., 2021⁴⁰40 Alkurt G, Murt A, Aydin Z, et al. Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey. PLoS One. 2021; 16(3):1-11.	Turkey	Exploratory/Transverse	119
S. Mandić R et al., 2020⁴¹41 Mandić-Rajčević S, Masci F, Crespi E, et al. Source and symptoms of COVID-19 among hospital workers in Milan. Occup Med (Lond). 2020 [acesso em 2020 maio 8]; 70(9):672-679. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798912/pdf/kqaa201.pdf https://www.ncbi.nlm.nih.gov/pmc/article...	Italy	Exploratory/Transverse	172
Schwartz K et al., 2020⁴²42 Schwartz KL, Achonu C, Buchan SA, et al. Epidemiology, clinical characteristics, household transmission, and lethality of severe acute respiratory syndrome coronavirus-2 infection among healthcare workers in Ontario, Canada. PLoS One. 2020; 15(12):1-12.	Canada	Exploratory/Transverse	7.050

Study	Age (years)	Gender (M/F)	Workplace	Probable Contamination
Alma T et al., 2020¹³13 Alma T, Bradley J, Bousema T, et al. Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands March 2020. Euro Surveill. 2020; (16):2000508.	41 to 50	21/79	Hospital	NS
Chen et al., 2020¹⁴14 Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020; 395(10223):507-13.	Average 55	NS	Hospital	Out-of-hospital
Eric J et al., 2020¹⁵15 Eric J, Chow MD, Noah G, et al. Symptom Screening at Illness Onset of Health Care Personnel With SARS-CoV-2 Infection in King County, Washington. JAMA. 2020; 323(20):2087-2089.	Average 43	11/37	Hospital	Workplace
Guan et al., 2020¹⁶16 Guan W, Ni Z, Hu Y, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382(18):1708-20.	Average 47	NS	Hospital	Out-of-hospital
Guo X et al., 2020¹⁷17 Guo X, Wang J, Hu D, et al. Survey of COVID-19 Disease Among Orthopaedic Surgeons in Wuhan, People’s Republic of China. J Bone Joint Surg Am. 2020; 102(10):847-854.	Average 36	23/1	Hospital	Workplace
Heinzerling et al., 2020¹⁸18 Heinzerling A. Transmission of COVID-19 to Health Care Personnel During Exposures to a Hospitalized Patient — Solano County, California, February 2020. MMWR. 2020; 69(15):472-476.	NS	20/101	Hospital	Workplace
Jiaojiao C et al., 2020¹⁹19 Jiaojiao C, Yang N, Wei Y, et al. Clinical Characteristics of 54 Medical Staff With COVID-19: A Retrospective Study in a Single Center in Wuhan, China. J Med Virol. 2020; 92(7):807-813.	Average 47	36/18	Hospital	NS
Keeley et al., 2020²⁰20 Keeley AJ, Evans C, Colton H, et al. Roll-out of SARS-CoV-2 testing for healthcare workers at a large NHS Foundation Trust in the United Kingdom, March 2020. Euro Surveill. 2020; 25(14):2000433.	NS	NS	Hospital	NS
Li Q et al., 2020²¹21 Li Q, Guan X, Wu P, et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. 2020; 382(13):1199-207.	Average 59	15/0	NS	Out-of-hospital
Liu, M et al., 2020²²22 Liu M, He P, Liu HG, et al. Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia. ResearchGate. 2020; 43(3):209-214.	Average 35	10/20	Hospital	Workplace
McMichael et al., 2020²³23 McMichael TM, Currie DW, Clark S, et al. Epidemiology of Covid-19 in a Long-Term Care Facility in King County Washington. N Engl J Med. 2020; 382(21):2005-11.	43 to 62	39/112	Hospital	Workplace
Qi Z et al., 2020²⁴24 Qi Z, Yin YL, Qiong L, et al. Spinal Anaesthesia for Patients With Coronavirus Disease 2019 and Possible Transmission Rates in Anaesthetists: Retrospective, Single-Centre, Observational Cohort Study. BJA. 2020; 124(6):670-675.	NS	14/30	Hospital	Workplace
Sun H et al., 2020²⁵25 Sun H, Lu M, Chen S, et al. Nosocomial SARS-CoV-2 infection among nurses in Wuhan at a single centre. J Infect. 2020; 80(6):e41-2.	22 to 56	4/28	Hospital	Workplace
Wang F et al., 2020²⁶26 Wang FD, Chen YY, Lee YM, et al. Positive Rate of Serum SARS-CoV Immunoglobulin G Antibody Among Healthcare Workers. Scand J Infect Dis. 2007; 39(92):152-156.	Average 33	F	Hospital	Workplace
Reusken et al., 2020²⁷27 Reusken CB, Buiting A, Bleeker-Rovers C, et al. Rapid assessment of regional SARS-CoV-2 community transmission through a convenience sample of healthcare workers, the Netherlands, March 2020. Euro Surveill. 2020; 25(12).	Average 56	NS	Hospital	Workplace
Ying-Hui et al., 2020²⁸28 Ying-Hui J, Huang Q, Wang YY, et al. Perceived Infection Transmission Routes, Infection Control Practices, Psychosocial Changes, and Management of COVID-19 Infected Healthcare Workers in a Tertiary Acute Care Hospital in Wuhan: A Cross-Sectional Survey. Mil Med Res. 2020; 11:7(1):24.	Average 35	39/64	Hospital	Workplace
Yu X et al., 2020²⁹29 Yu X, Sun X, Cui P, et al. Epidemiological and clinical characteristics of 333 confirmed cases with coronavirus disease 2019 in Shanghai, China. Transbound Emerg Dis. 2020; 67(4):697-1707.	Average 50	M	Hospital	Workplace
Escribese M et al., 2020³⁰30 Escribese MM, Nistal-Villan E, Fernandez P, et al. Cross-sectional pilot study exploring the feasibility of a rapid SARS-CoV-2 immunization test in health and nonhealthcare workers. Allergy. 2020; 76(3):896-899.	NS	21/29	Hospital	Workplace
Marra M et al., 2021³¹31 Marra A, Generali D, Zagami P, et al. Seroconversion in patients with cancer and oncology health care workers infected by SARS-CoV-2. Ann Oncol. 2021; 32(1):113-19.	Average 46	29/76	Hospital	Workplace
Ying- Hui J et al., 2020³²32 Jin YH, Huang Q, Wang YY, et al. Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey. Mil Med Res. 2020; 7(1):24.	Average 35	39/64	Hospital	Workplace
Fwoloshi S et al., 2020³³33 Fwoloshi S, Hines JZ, Barradas DT, et al. Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) among Health Care Workers—Zambia, July 2020. Clin Infect Dis. 2021 [acesso em 2021 jun 24]; ciab273. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083617/pdf/ciab273.pdf https://www.ncbi.nlm.nih.gov/pmc/article...	20 to 39	222/438	Hospital	NS
Lombardi A et al., 2020³⁴34 Lombardi A, Consonni D, Carugno M, et al. Characteristics of 1573 healthcare workers who underwent nasopharyngeal swab testing for SARS-CoV-2 in Milan, Lombardy, Italy. Clin Microbiol Infect. 2020; 26:1413:e9e1413.e13.	30 to 60	57/82	Hospital	Workplace
Lahner E et al., 2020³⁵35 Lahner E, Dilaghi E, Prestigiacomo C, et al. Prevalence of Sars-Cov-2 infection in health workers (HWs) and diagnostic test performance: the experience of a teaching hospital in central Italy. Int J Environ Res Public Health. 2020; 17(12):4417.	Average 41	F	Hospital	Workplace and Out-of-hospital
Al-Kuwari MG et al., 2021³⁶36 Al-Kuwari MG, AbdulMalik MA, Al-Nuaimi AA, et al. Epidemiology Characteristics of COVID-19 Infection Amongst Primary Health Care Workers in Qatar: March-October 2020. Front Public Health. 2021; (9):1-6.	Average 36	711/488	Primary care	NS
Liu J et al., 2021³⁷37 Liu J, Ouyang L, Yang D, et al. Epidemiological, clinical, radiological characteristics and outcomes of medical staff with COVID-19 in Wuhan, China: Analysis of 101 cases. Int J Med Sci. 2021; 18(6):1492-1501.	Average 33	32/69	Hospital	Workplace
Abdelmoniem R et al., 2020³⁸38 Abdelmoniem R, Fouad R, Shawky S, et al. SARS-CoV-2 infection among asymptomatic healthcare workers of the emergency department in a tertiary care facility. J Clin Virol. 2021; (134):104710.	Average 31,7	13/16	Hospital	Workplace
Rodriguez A et al., 2021³⁹39 Rodriguez A, Arrizabalaga-Asenjo M, Fernandez-Baca V. Seroprevalence of SARS-CoV-2 antibody among healthcare workers in a university hospital in Mallorca, Spain, during the first wave of the COVID-19 pandemic Adrian. Int J Infect Dis. 2021; (105):482-486.	Average 42	F	Hospital	Workplace
Alkurt G et al., 2021⁴⁰40 Alkurt G, Murt A, Aydin Z, et al. Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey. PLoS One. 2021; 16(3):1-11.	Average 36,2	39/80	Hospital	NS
S. Mandić R et al., 2020⁴¹41 Mandić-Rajčević S, Masci F, Crespi E, et al. Source and symptoms of COVID-19 among hospital workers in Milan. Occup Med (Lond). 2020 [acesso em 2020 maio 8]; 70(9):672-679. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798912/pdf/kqaa201.pdf https://www.ncbi.nlm.nih.gov/pmc/article...	Average 44	73/99	Hospital	Workplace
Schwartz K et al., 2020⁴²42 Schwartz KL, Achonu C, Buchan SA, et al. Epidemiology, clinical characteristics, household transmission, and lethality of severe acute respiratory syndrome coronavirus-2 infection among healthcare workers in Ontario, Canada. PLoS One. 2020; 15(12):1-12.	30 to 70	F	NS	NS

Professional category	n	%
Nursing professionals^* * Includes nursing workers not separated by professional category/hierarchy, such as nurses and registered nurses, common nomenlature in the US.	2,939	27.3
Physicians^ Includes physicians and resident physicians.	1,422	13.2
Other health professionals^* ***** It includes physiotherapists, pharmacists, occupational therapists, psychologists, dentists and support workers.	582	5.4
Not identified	5,817	54.1
Total	10,760	100

[1] *
Orcid (Open Researcher and Contributor ID).

Brasil

Brasil

Characteristics of health professionals affected by Covid-19: an integrative literature review

ABSTRACT