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A seroprevalence of measles antibodies of a children population of Botucatu, São Paulo State, Brazil

A study of the seroprevalence of measles antibodies was conducted in a population of children residing in Botucatu, SP, in order to asses their immunological status whether induced by natural infection or by vaccination. A total of 101 children were studied, all of which had been vaccinated against measles. The laboratory tests used to determine the presence of antibodies in the collected blood samples were hemagglutination inhibition (HI) and immunoenzymatic assay (ELISA). HI results showed that 92.1% of the samples presented antibodies against measles. Samples with titers <1:4 when studied by HI were retested by ELISA in the same laboratory and only two continued to be negative for measles antibodies. Thus, measles antibodies were present in 98% of the serum samples from the children studied.

Measles; Vaccine; Seroprevalence


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