Lima, Maria Amanda Correia; Cunha, Gilmara Holanda da; Galvão, Marli Teresinha Gimeniz; Rocha, Ryvanne Paulino; Franco, Kátia Barbosa; Fontenele, Marina Soares Monteiro

doi:10.1590/0034-7167-2016-0416

Maria Amanda Correia Lima

Universidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

Gilmara Holanda da Cunha CORRESPONDING AUTHOR Gilmara Holanda da Cunha E-mail: gilmaraholandaufc@yahoo.com.br

Universidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

Universidade Federal do Ceará, Department of Nursing, Research Group and Center of Studies on HIV/AIDS and Associated Diseases. Fortaleza, Ceará, Brazil.

Marli Teresinha Gimeniz Galvão

Universidade Federal do Ceará, Department of Nursing, Research Group and Center of Studies on HIV/AIDS and Associated Diseases. Fortaleza, Ceará, Brazil.

Ryvanne Paulino Rocha

Universidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

Kátia Barbosa Franco

Universidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

Marina Soares Monteiro Fontenele

Universidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

CORRESPONDING AUTHOR Gilmara Holanda da Cunha E-mail: gilmaraholandaufc@yahoo.com.br

Title	Year/ Country	Study outline/number of patients	Intervention	Outcome
Prevalence and patient awareness of medical comorbidities in an urban AIDS clinic⁽¹⁸18 Weiss JJ, Osorio G, Ryan E, Marcus SM, Fishbein DA. Prevalence and Patient Awareness of Medical Comorbidities in an Urban Aids Clinic. AIDS Patient Care STDS [Internet]. 2010[cited 2016 May 14];24(1):39-48. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859780/pdf/apc.2009.0152.pdf http://www.ncbi.nlm.nih.gov/pmc/articles... ⁾	United States 2010	Cross-sectional n = 200	Interview with use of a form	Prevalence of SAH on 27.5% black people.
Chronic illness burden and quality of life in an aging HIV population⁽¹⁹19 Balderson BH, Grothaus L, Harrison RG, Mccoy K, Mahoney C, Catz S. Chronic illness burden and quality of life in an aging HIV population. AIDS Care [Internet]. 2013[cited 2016 May 16];25(4):451-8. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535557/pdf/caic25_451.pdf http://www.ncbi.nlm.nih.gov/pmc/articles... ⁾	United States 2013	Cross-sectional n = 452	Interview on the phone	Prevalence of SAH on 46% people aged 50 or older.
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS⁽¹⁰10 Arruda Junior ER, Lacerda HR, Moura LCRV, Albuquerque MFPM, Miranda Filho DB, Diniz GT, et al. Risk factors related to hypertension among patients in a cohort living with HIV/AIDS. Braz J Infect Dis [Internet]. 2010[cited 2016 May 16];14(3):281-7. Available from: http://www.scielo.br/pdf/bjid/v14n3/v14n3a14.pdf http://www.scielo.br/pdf/bjid/v14n3/v14n... ⁾	Brazil 2010	Case control n = 958	Observing groups Case: patients with AP (Arterial Pressure) > 140/90 mmHg, at least on two occasions, or previous diagnosis of hypertension. Control: patients with normal AP	Prevalence of SAH in 25.6% people followed up in the clinic.
Risco cardiovascular: marcadores antropométricos, clínicos e dietéticos em indivíduos infectados pelo vírus HIV⁽¹¹11 Leite LHM, Sampaio ABMM. Risco cardiovascular: marcadores antropométricos, clínicos e dietéticos em indivíduos infectados pelo vírus HIV. Rev Nutr [Internet]. 2011[cited 2016 May 13];24(1):79-88. Available from: http://www.scielo.br/pdf/rn/v24n1/v24n1a08.pdf http://www.scielo.br/pdf/rn/v24n1/v24n1a... ⁾	Brazil 2011	Cross-sectional n = 100	Interview and physical examination	Prevalence of SAH in 35% people followed up in the clinic.
What should we know about metabolic syndrome and lipodystrophy in AIDS⁽¹²12 Signorini DJHP, Monteiro MCM, Andrade MFC, Signorini DH, Eyer-Silva WA. What should we know about metabolic syndrome and lipodystrophy in AIDS? Rev Assoc Med Bras [Internet]. 2011[cited 2016 May 15];58(1):70-5. Available from: http://www.scielo.br/pdf/ramb/v58n1/v58n1a17.pdf http://www.scielo.br/pdf/ramb/v58n1/v58n... ⁾	Brazil 2011	Cross-sectional n = 819	Interview and physical examination	Prevalence of SAH in 16.7% people followed up in the clinic.
Aging with HIV: an overview of an urban cohort in Rio de Janeiro (Brazil) across decades of life⁽¹⁴14 Torres TS, Cardoso SW, Velasque LS, Marins LMS, Oliveira MS, Veloso VG, et al. Aging with HIV: an overview of an urban cohort in Rio de Janeiro (Brazil) across decades of life. Braz J Infect Dis [Internet]. 2013[cited 2016 May 15];17(3):324-31. Available from: http://www.sciencedirect.com/science/article/pii/S1413867013000640 http://www.sciencedirect.com/science/art... ⁾	Brazil 2013	Cross-sectional n = 2.307	Medical Record	Prevalence of SAH in 11.9% people followed up in the clinic.
Risk of coronary artery disease in individuals infected with human immunodeficiency virus⁽¹⁵15 Vilela FD, Lorenzo AR, Tura BR, Ferraiuoli GI, Hadlich M, Barros MVL, et al. Risk of coronary artery disease in individuals infected with human immunodeficiency virus. Braz J Infect Dis [Internet]. 2011[cited 2016 May 15];15(6):521-7. Available from: http://www.scielo.br/pdf/bjid/v15n6/v15n6a04.pdf http://www.scielo.br/pdf/bjid/v15n6/v15n... ⁾	Brazil 2011	Cross-sectional n = 40		Prevalence of SAH in 55% people followed up in the clinic.
Correlates of hypertension in patients with AIDS in the era of highly-active antiretroviral therapy⁽²⁰20 Krauskopf K, Natta MLV, Danis RP, Gangaputra S, Ackatz L, Addessi A, et al. Correlates of hypertension in patients with AIDS in the era of highly-active antiretroviral therapy. J Int Assoc Provid AIDS Care [Internet]. 2013[cited 2016 May 17];12(5):325-33. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100586/pdf/nihms598762.pdf http://www.ncbi.nlm.nih.gov/pmc/articles... ⁾	United States 2013	Prospective cohort n = 2390	Interview, medical record and examinations	Prevalence of SAH on 22% and incidence in 64.1/1000.
Impact of highly active antiretroviral therapy on blood pressure in HIV-infected patients. A prospective study in a cohort of naive patients⁽²³23 Palacios R, Santos J, García A, Castells E, González M, Ruiz J, et al. Impact of highly active antiretroviral therapy on blood pressure in HIV-infected patients: a prospective study in a cohort of naive patients. HIV Med [Internet]. 2006 [cited 2016 May 20];7(1):10-5. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1468-1293.2005.00333.x/epdf http://onlinelibrary.wiley.com/doi/10.11... ⁾	Spain 2006	Prospective cohort n = 95	Interview and physical examination	Before ART^† † TARV: Terapia antirretroviral; , 7% patients had SAH; After 48 weeks of ART, 26% were with high AP^‡ ‡ PA: Pressão arterial. .
Lipid profile, cardiovascular risk factors and metabolic syndrome in a group of AIDS patients⁽¹³13 Silva EFR, Bassichetto KC, Lewi DS. Lipid Profile, Cardiovascular Risk Factors and Metabolic Syndrome in a Group of AIDS Patients. Arq Bras Cardiol [Internet]. 2008[cited 2016 Jun 15];93(2):113-8. Available from: http://www.scielo.br/pdf/abc/v93n2/en_v93n2a08.pdf http://www.scielo.br/pdf/abc/v93n2/en_v9... ⁾	Brazil 2008	Cross-sectional n = 252	Interview and physical examination	In use of ART: 19.9% patients had SAH; No use of ART: 13.3% had SAH.
Prevalence of hypertension in HIV/AIDS patients on highly active antiretroviral therapy (haart) compared with haart naïve patients at the limbe regional hospital, Cameroon⁽²⁵25 Dimala CA, Atashili J, Mbuagbaw JC, Wilfred A, Monekosso GL. Prevalence of hypertension in HIV/AIDS patients on highly active antiretroviral therapy (HAART) compared with HAART Naïve Patients at the Limbe Regional Hospital, Cameroon. PLoS One [Internet]. 2016[cited 2016 May 16];11(2):1-11. Available from: http://journals.plos.org/plosone/article/asset?id=10.1371%2Fjournal.pone.0148100.PDF http://journals.plos.org/plosone/article... ⁾	Cameroon 2016	Cross-sectional n = 200	Interview and physical examination	In use of ART: 38% patients had SAH; No use of ART: 19% had SAH.

Title	Year/ Country	Study outline/ number of patients	Intervention	Outcome
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS⁽¹⁰10 Arruda Junior ER, Lacerda HR, Moura LCRV, Albuquerque MFPM, Miranda Filho DB, Diniz GT, et al. Risk factors related to hypertension among patients in a cohort living with HIV/AIDS. Braz J Infect Dis [Internet]. 2010[cited 2016 May 16];14(3):281-7. Available from: http://www.scielo.br/pdf/bjid/v14n3/v14n3a14.pdf http://www.scielo.br/pdf/bjid/v14n3/v14n... ⁾	Brazil 2010	Case control n = 958	Observing groups Case: patients with AP > 140/90 mmHg, at least on two occasions, or previous diagnosis of hypertension. Control: patients with normal AP	– Advanced age – Longest time of anti-HIV positive serology – Use of ART: – SAH ^† † SAH: Systemic Arterial Hypertension; family history – Low CD4+ T lymphocytes – Sedentariness: – BMI ^‡ ‡ BMI:Body Mass Index > 25 kg/m – High Waist Circumference – Triglycerides > 150 mg/dL – Blood Glucose > 100 mg/dL – Cholesterol > 200 mg/dL
What should we know about metabolic syndrome and lipodystrophy in AIDS?⁽¹²12 Signorini DJHP, Monteiro MCM, Andrade MFC, Signorini DH, Eyer-Silva WA. What should we know about metabolic syndrome and lipodystrophy in AIDS? Rev Assoc Med Bras [Internet]. 2011[cited 2016 May 15];58(1):70-5. Available from: http://www.scielo.br/pdf/ramb/v58n1/v58n1a17.pdf http://www.scielo.br/pdf/ramb/v58n1/v58n... ⁾	Brazil 2011	Cross-sectional n = 819	Interview and physical examination	– Advanced age – Longest time of anti-HIV positive serology – Use of ART: – High CD4+ T lymphocytes – BMI ^‡ ‡ BMI:Body Mass Index > 25 kg/m
Aging with HIV: an overview of an urban cohort in Rio de Janeiro (Brazil) across decades of life⁽¹⁴14 Torres TS, Cardoso SW, Velasque LS, Marins LMS, Oliveira MS, Veloso VG, et al. Aging with HIV: an overview of an urban cohort in Rio de Janeiro (Brazil) across decades of life. Braz J Infect Dis [Internet]. 2013[cited 2016 May 15];17(3):324-31. Available from: http://www.sciencedirect.com/science/article/pii/S1413867013000640 http://www.sciencedirect.com/science/art... ⁾	Brazil 2013	Cross-sectional n = 2307	Analysis on medical records	– Advanced age
Hospitalizations for cardiovascular disease in african americans and whites with HIV/AIDS⁽¹⁶16 Oramasionwu CU, Morse GD, Lawson KA, Brown CM, Koeller JM, Frei CR. Hospitalizations for Cardiovascular Disease in African Americans and Whites with HIV/AIDS. Popul Health Manag [Internet]. 2013[cited 2016 May 23];16(3):201-7. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840471/pdf/pop.2012.0043.pdf http://www.ncbi.nlm.nih.gov/pmc/articles... ⁾	United States 2013	Retrospective cohort n = 288	Medical records analysis	– Advanced age – Black – Women – Chronic Kidney Disease
Chronic illness burden and quality of life in an aging HIV population⁽¹⁹19 Balderson BH, Grothaus L, Harrison RG, Mccoy K, Mahoney C, Catz S. Chronic illness burden and quality of life in an aging HIV population. AIDS Care [Internet]. 2013[cited 2016 May 16];25(4):451-8. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535557/pdf/caic25_451.pdf http://www.ncbi.nlm.nih.gov/pmc/articles... ⁾	United States 2013	Cross-sectional n = 452	Interview on the phone	– Advanced age – Stress and depression – Low social and mental activity
Correlates of hypertension in patients with AIDS in the era of highly-active antiretroviral therapy⁽²⁰20 Krauskopf K, Natta MLV, Danis RP, Gangaputra S, Ackatz L, Addessi A, et al. Correlates of hypertension in patients with AIDS in the era of highly-active antiretroviral therapy. J Int Assoc Provid AIDS Care [Internet]. 2013[cited 2016 May 17];12(5):325-33. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100586/pdf/nihms598762.pdf http://www.ncbi.nlm.nih.gov/pmc/articles... ⁾	United States 2013	Retrospective cohort n = 2390	Interview, medical records analysis and examinations	– Advanced age – Black – Diabetes Mellitus – Low educational level – High weight – Triglycerides > 150 mg/dL
Hipertensión arterial, infección por el virus de la inmunodeficiencia humana y tratamiento antirretrovírico de gran actividad⁽²¹21 Serna JIB, Zamora FX, Montes ML, García-Puig J, Arribas JR. Hipertensión arterial, infección por el virus de la inmunodeficiencia humana y tratamiento antirretrovírico de gran actividad. Enferm Infecc Microbiol Clin [Internet]. 2010[cited 2016 May 15];28(1):32-7. Available from: http://www.elsevier.es/es-revista-enfermedades-infecciosas-microbiologia-clinica-28-pdf-S0213005X09001062-S300 http://www.elsevier.es/es-revista-enferm... ⁾	Spain 2010	Integrative review	Search on MEDLINE database	– Advanced age – Men – Low pre-treatment systolic pressure with ART – Low CD4+ T lymphocytes – Chronic kidney disease – Lipodystrophy – High Waist Circumference – Triglycerides > 150 mg/dL – Cholesterol > 200 mg/dL
Impact of highly active antiretroviral therapy on blood pressure in HIV-infected patients. A prospective study in a cohort of naive patients⁽²³23 Palacios R, Santos J, García A, Castells E, González M, Ruiz J, et al. Impact of highly active antiretroviral therapy on blood pressure in HIV-infected patients: a prospective study in a cohort of naive patients. HIV Med [Internet]. 2006 [cited 2016 May 20];7(1):10-5. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1468-1293.2005.00333.x/epdf http://onlinelibrary.wiley.com/doi/10.11... ⁾	Spain 2006	Retrospective cohort n = 95	Interview and physical examination	– Advanced age – Low CD4+ T lymphocytes – BMI ^‡ ‡ BMI:Body Mass Index > 25 kg/m – Triglycerides > 150 mg/dL – Cholesterol > 200 mg/dL
Prevalence of hypertension in HIV/AIDS Patients on highly active antiretroviral therapy (HAART) compared with HAART naive patients at the limbe regional hospital, Cameroon⁽²⁵25 Dimala CA, Atashili J, Mbuagbaw JC, Wilfred A, Monekosso GL. Prevalence of hypertension in HIV/AIDS patients on highly active antiretroviral therapy (HAART) compared with HAART Naïve Patients at the Limbe Regional Hospital, Cameroon. PLoS One [Internet]. 2016[cited 2016 May 16];11(2):1-11. Available from: http://journals.plos.org/plosone/article/asset?id=10.1371%2Fjournal.pone.0148100.PDF http://journals.plos.org/plosone/article... ⁾	Cameroon 2016	Cross-sectional n = 200	Interview and physical examination	– Advanced age – Men – Use of ART:
Prevalence and patient awareness of medical comorbidities in an urban AIDS clinic⁽¹⁸18 Weiss JJ, Osorio G, Ryan E, Marcus SM, Fishbein DA. Prevalence and Patient Awareness of Medical Comorbidities in an Urban Aids Clinic. AIDS Patient Care STDS [Internet]. 2010[cited 2016 May 14];24(1):39-48. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859780/pdf/apc.2009.0152.pdf http://www.ncbi.nlm.nih.gov/pmc/articles... ⁾	United States 2010	Cross-sectional n = 200	Filling out cards, interview and medical records	– Women – Longest time of anti-HIV positive serology – Use of ART:
Cardiovascular profile and events of US adults 20-49 years with HIV: results from the NHANES 1999-2008⁽¹⁷17 Gutierrez J, Elkind MSV, Marshall RS. Cardiovascular profile and events of US adults 20-49 years with HIV: results from the nhanes 1999-2008. AIDS Care [Internet]. 2013[cited 2016 May 1];25(11):1385-91. Available from: http://www.tandfonline.com/doi/abs/10.1080/09540121.2013.769493?journalCode=caic20 http://www.tandfonline.com/doi/abs/10.10... ⁾	United States 2013	Cross-sectional n = 12.339	Data analysis of the National Center for Health Statistics.	– Longest time of anti-HIV positive serology
Lipid profile, cardiovascular risk factors and metabolic syndrome in a group of AIDS patients⁽¹³13 Silva EFR, Bassichetto KC, Lewi DS. Lipid Profile, Cardiovascular Risk Factors and Metabolic Syndrome in a Group of AIDS Patients. Arq Bras Cardiol [Internet]. 2008[cited 2016 Jun 15];93(2):113-8. Available from: http://www.scielo.br/pdf/abc/v93n2/en_v93n2a08.pdf http://www.scielo.br/pdf/abc/v93n2/en_v9... ⁾	Brazil 2008	Cross-sectional n = 252	Interview and physical examination	– Diabetes Mellitus – Arteriosclerosis – Smoking
Risco cardiovascular: marcadores antropométricos, clínicos e dietéticos em indivíduos infectados pelo vírus HIV⁽¹¹11 Leite LHM, Sampaio ABMM. Risco cardiovascular: marcadores antropométricos, clínicos e dietéticos em indivíduos infectados pelo vírus HIV. Rev Nutr [Internet]. 2011[cited 2016 May 13];24(1):79-88. Available from: http://www.scielo.br/pdf/rn/v24n1/v24n1a08.pdf http://www.scielo.br/pdf/rn/v24n1/v24n1a... ⁾	Brazil 2011	Cross-sectional n = 100	Interview and physical examination	– Smoking – Blood Glucose > 100 mg/dL – Cholesterol > 200 mg/dL – Low values of high density lipoproteins

Title	Year/ Country	Study outline/ number of patients	Intervention	Outcome
Hipertensión arterial en pacientes infectados por el virus de la inmunodeficiencia humana⁽²²22 Galvañ VG, Puerto MJG, Mas JR. Hipertensión arterial en pacientes infectados por el virus de la inmunodeficiencia humana. Hipertensión [Internet]. 2003[cited 2016 May 15];20(2):63-73. Available from: http://www.elsevier.es/es-revista-hipertension-riesgo-vascular-67-pdf-S1889183703713518-S300 http://www.elsevier.es/es-revista-hipert... ⁾	Spain 2013	Integrative review	Search in database	– Protease inhibitors (ritonavir, indinavir, saquinavir, lopinavir, nelfinavir and amprenavir): Increase of AP^* * AP: Arterial Pressure and potentialization or decrease of the effect of calcium channel blockers. – Nevirapine: Interaction with calcium channel blockers – Delavirdine: Increases plasmatic levels of antihypertensive medicines
Cardiovascular manifestations of HIV infection⁽²⁴24 Barbaro G. Cardiovascular manifestations of HIV infection. J R Soc Med [Internet]. 2001[cited 2016 May 4];94(8):384-90. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1281631/pdf/0940384.pdf http://www.ncbi.nlm.nih.gov/pmc/articles... ⁾	Italy 2001	Integrative review	Search in database	– Protease inhibitors (ritonavir, indinavir, saquinavir, lopinavir, nelfinavir and amprenavir): Coronary artery disease, lipodystrophy, insulin resistance, high cholesterol, high triglycerides and infarction.
Una década de terapia anti-retroviral: perfil de pacientes con 10 años de triterapia de alta efectividad⁽²⁶26 Wilson G, Wolff M. Una década de terapia anti-retroviral: Perfil de pacientes con 10 años de triterapia de alta efectividad. Rev Chilena Infectol [Internet]. 2012[cited 2016 May 14];29(3):337-43. Available from: http://www.scielo.cl/pdf/rci/v29n3/art15.pdf http://www.scielo.cl/pdf/rci/v29n3/art15... ⁾	Chile 2012	Retrospective cohort	Medical records analysis	– Lipodystrophy – High triglycerides

[1] CORRESPONDING AUTHOR Gilmara Holanda da Cunha E-mail: gilmaraholandaufc@yahoo.com.br

Brasil

Brasil

Hipertensión arterial sistémica en personas que viven con VIH/Sida: revisión integradora

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