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Minimum minimorum: thyroid minimally invasive FNA, less is more concept? Volens nolens?

A Deucalione, diagnosis for the crucial endocrine organ, the thyroid, remains significant to date. Bonitas non est pessimis esse meliorem. Furthermore, the butterfly-shaped gland, being necessitated a delicate deal, is apparent11 Sengul I, Sengul D. Proposal of a novel terminology: minimally invasive FNA and thyroid minimally invasive FNA; MIFNA and thyroid MIFNA. Ann Ital Chir. 2021;92:330-1. PMID: 34312332.33 Sengul I, Sengul D, Veiga ECA. Revisiting optimal needle size for thyroid fine-needle aspiration cytology: not much finer, less non-diagnostic? Rev Assoc Med Bras. 2021;67(9):1213-4. https://doi.org/10.1590/1806-9282.20210671
https://doi.org/10.1590/1806-9282.202106...
. In thyroidology, image-guided interventional techniques have globally been noticed and increasingly harnessed over the past four decades44 Baloch Z, LiVolsi VA. Fifty years of thyroid pathology: concepts and developments. Hum Pathol. 2020;95:46-54. https://doi.org/10.1016/j.humpath.2019.09.008
https://doi.org/10.1016/j.humpath.2019.0...
. Bene diagnoscitur, bene curatur. Having said that, a dynamic discipline, thyroid cytopathology, still harbors a highly controversial issue, id est, indeterminate cytology, resulting in an ongoing debate44 Baloch Z, LiVolsi VA. Fifty years of thyroid pathology: concepts and developments. Hum Pathol. 2020;95:46-54. https://doi.org/10.1016/j.humpath.2019.09.008
https://doi.org/10.1016/j.humpath.2019.0...
1111 Sengul I, Sengul D. Big gain, no pain: thyroid minimally invasive FNA (Thy MIFNA); proposal of novelty in terminology. Rev Assoc Med Bras. 2021;67(12):1749-50. https://doi.org/10.1590/1806-9282.20210922
https://doi.org/10.1590/1806-9282.202109...
. Despite the roles of sonography and fine-needle aspiration (FNA) are well-established globally for contributing to rule out blurred lines55 Sengul I, Sengul D. Blurred lines for management of thyroid nodules in the era of AUS/FLUS: novel subdivisions of category IIIA and IIIB in a possible forthcoming TBSRTC, 3rd ed.; amending vs. unnecessary? Rev Assoc Med Bras. 2021;67(10):1385-6. https://doi.org/10.1590/1806-9282.20210763.
https://doi.org/10.1590/1806-9282.202107...
88 Sengul D, Sengul I, Egrioglu E, Ozturk T, Aydın I, Kesicioglu T, et al. Can cut-off points of 10 and 15 mm of thyroid nodule predict malignancy on the basis of three diagnostic tools: i) strain elastography, ii) the Bethesda System for Reporting Thyroid Cytology with 27-gauge fine-needle, and iii) histopathology? J BUON. 2020;25(2):1122-9. PMID: 32521915 in the diagnosis of thyroid nodules, to the best of our knowledge, the ideal needle size has not been stated in a released, well-accepted management guideline to date11 Sengul I, Sengul D. Proposal of a novel terminology: minimally invasive FNA and thyroid minimally invasive FNA; MIFNA and thyroid MIFNA. Ann Ital Chir. 2021;92:330-1. PMID: 34312332.33 Sengul I, Sengul D, Veiga ECA. Revisiting optimal needle size for thyroid fine-needle aspiration cytology: not much finer, less non-diagnostic? Rev Assoc Med Bras. 2021;67(9):1213-4. https://doi.org/10.1590/1806-9282.20210671
https://doi.org/10.1590/1806-9282.202106...
,1212 Maeda H, Kutomi G, Satomi F, Shima H, Mori M, Hirata K, et al. Clinicopathological characteristics of thyroid cancer misdiagnosed by fine needle aspiration. Exp Ther Med. 2016;12(4):2766-72. https://doi.org/10.3892/etm.2016.3651
https://doi.org/10.3892/etm.2016.3651...
1616 Tanaka A, Hirokawa M, Higuchi M, Kanematsu R, Suzuki A, Kuma S, et al. Optimal needle size for thyroid fine needle aspiration cytology. Endocr J. 2019;66(2):143-7. https://doi.org/10.1507/endocrj.EJ18-0422
https://doi.org/10.1507/endocrj.EJ18-042...
. However, the adequacy of the finer and thicker needles has been proclaimed as similar by many authors1313 Cerit M, Yücel C, Göçün PU, Poyraz A, Cerit ET, Taneri F. Ultrasound-guided thyroid nodule fine-needle biopsies--comparison of sample adequacy with different sampling techniques, different needle sizes, and with/without onsite cytological analysis. Endokrynol Pol. 2015;66(4):295-300. https://doi.org/10.5603/EP.2015.0037
https://doi.org/10.5603/EP.2015.0037...
, though the latter has unfortunately been utilized frequently. We have reported an FNA serial of “non Deucalione, sed, a decennium” by the surgeon-performed ultrasonography (SUS) with the 27-G needles with a reasonable rate of nondiagnostic cytology. Will it be evaluated and accepted as “less is more concept”? Volens nolens? We had utilized the additional administration of preprocedural topical and local anesthesia in SUS-based serial during this decade and, ad hoc, have currently presented and recommended a novel term, “Thyroid minimally invasive FNA” (Thy MIFNA)11 Sengul I, Sengul D. Proposal of a novel terminology: minimally invasive FNA and thyroid minimally invasive FNA; MIFNA and thyroid MIFNA. Ann Ital Chir. 2021;92:330-1. PMID: 34312332.33 Sengul I, Sengul D, Veiga ECA. Revisiting optimal needle size for thyroid fine-needle aspiration cytology: not much finer, less non-diagnostic? Rev Assoc Med Bras. 2021;67(9):1213-4. https://doi.org/10.1590/1806-9282.20210671
https://doi.org/10.1590/1806-9282.202106...
,1111 Sengul I, Sengul D. Big gain, no pain: thyroid minimally invasive FNA (Thy MIFNA); proposal of novelty in terminology. Rev Assoc Med Bras. 2021;67(12):1749-50. https://doi.org/10.1590/1806-9282.20210922
https://doi.org/10.1590/1806-9282.202109...
, contributing in thyroidology. Minimum minimorum? Adequatio intellectus et rei? Dum vivimus servimus.

  • Funding: none.

ACKNOWLEDGMENTS

The authors thank all the participants of this article.

REFERENCES

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    Sengul I, Sengul D. Delicate needle with the finest gauge for a butterfly gland, the thyroid: is it worth mentioning? Sanamed. 2021;16(2):173-4. https://doi.org/10.24125/sanamed.v16i2.515
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    » https://doi.org/10.1590/1806-9282.20210671
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    » https://doi.org/10.1016/j.humpath.2019.09.008
  • 5
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    » https://doi.org/10.1590/1806-9282.20210763
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    Sengul I, Sengul D. Focusing on thyroid nodules in suspense: 10-15 mm with repeat cytology, Category III, the Bethesda System for Reporting Thyroid Cytopathology, TBSRTC. Rev Assoc Med Bras. 2021;67(2):166-7. https://doi.org/10.1590/1806-9282.67.02.20200828
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    Sengul D, Sengul I, Egrioglu E, Ozturk T, Aydın I, Kesicioglu T, et al. Can cut-off points of 10 and 15 mm of thyroid nodule predict malignancy on the basis of three diagnostic tools: i) strain elastography, ii) the Bethesda System for Reporting Thyroid Cytology with 27-gauge fine-needle, and iii) histopathology? J BUON. 2020;25(2):1122-9. PMID: 32521915
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    Sengul D, Sengul I, Pelikán A. Paraphrase for the impact of repeat fine-needle aspiration in thyroid nodules categorized as atypia of undetermined significance or follicular lesion of undetermined significance: a single center experience. Diagn Cytopathol. 2021;49(3):452-3. https://doi.org/10.1002/dc.24685
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    Sengul I, Sengul D. Big gain, no pain: thyroid minimally invasive FNA (Thy MIFNA); proposal of novelty in terminology. Rev Assoc Med Bras. 2021;67(12):1749-50. https://doi.org/10.1590/1806-9282.20210922
    » https://doi.org/10.1590/1806-9282.20210922
  • 12
    Maeda H, Kutomi G, Satomi F, Shima H, Mori M, Hirata K, et al. Clinicopathological characteristics of thyroid cancer misdiagnosed by fine needle aspiration. Exp Ther Med. 2016;12(4):2766-72. https://doi.org/10.3892/etm.2016.3651
    » https://doi.org/10.3892/etm.2016.3651
  • 13
    Cerit M, Yücel C, Göçün PU, Poyraz A, Cerit ET, Taneri F. Ultrasound-guided thyroid nodule fine-needle biopsies--comparison of sample adequacy with different sampling techniques, different needle sizes, and with/without onsite cytological analysis. Endokrynol Pol. 2015;66(4):295-300. https://doi.org/10.5603/EP.2015.0037
    » https://doi.org/10.5603/EP.2015.0037
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    Hanbidge AE, Arenson AM, Shaw PA, Szalai JP, Hamilton PA, Leonhardt C. Needle size and sample adequacy in ultrasound-guided biopsy of thyroid nodules. Can Assoc Radiol J. 1995;46(3):199-201. PMID: 7538881
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    Zhang L, Liu Y, Tan X, Liu X, Zhang H, Qian L. Comparison of different-gauge needles for fine-needle aspiration biopsy of thyroid nodules. J Ultrasound Med. 2018;37(7):1713-6. https://doi.org/10.1002/jum.14521
    » https://doi.org/10.1002/jum.14521
  • 16
    Tanaka A, Hirokawa M, Higuchi M, Kanematsu R, Suzuki A, Kuma S, et al. Optimal needle size for thyroid fine needle aspiration cytology. Endocr J. 2019;66(2):143-7. https://doi.org/10.1507/endocrj.EJ18-0422
    » https://doi.org/10.1507/endocrj.EJ18-0422

Publication Dates

  • Publication in this collection
    15 Apr 2022
  • Date of issue
    Mar 2022

History

  • Received
    20 Nov 2021
  • Accepted
    24 Nov 2021
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