Abstract
Several novel bioactive components isolated from Chinese medicinal plants will be presented. These include novel maytansinoid tumor, inhibitors, some new ent-kaurane and rosane diterpenoids from Mallotus anomalus Meer et Chun (Euphorbiaceae), as well asnovel insecticide, stemona alkaloids from Stemona parviflora C. H. Wright (Stemonaceae). Both are native plants of Hainan island, Chine. 2D NMR techniques such as mono and hetero-COSY, NOESY, COLOC as well as H-NMR line broadening effect were utilized for structure elucidation. The separation techniques, struture elucidations and bioassay results will be reported.
Mallotus anomalus; Euphorbiaceae; Stemona parviflora; Stemonoceae; ent-kourane; rosane; delabradane diterpenoids; mayatansinoid; stemona alkaloids; 2D NMR techniques
Studies on bioactive components from Chinese medicinal plants
Ren-Sheng Xu1
Zong-Jian Tang1
Sheng-Chu Feng1
Yi-Ping Yang1
Wen-Han Lin1
Qiong-Xing Zhong2
Yi Zhong1
Academia Sinica, Shanghai Institute of Materia Medica, Shanghai, China
Hainan Normal College, Hainan, China
Several novel bioactive components isolated from Chinese medicinal plants will be presented. These include novel maytansinoid tumor, inhibitors, some new ent-kaurane and rosane diterpenoids from Mallotus anomalus Meer et Chun (Euphorbiaceae), as well asnovel insecticide, stemona alkaloids from Stemona parviflora C. H. Wright (Stemonaceae). Both are native plants of Hainan island, Chine. 2D NMR techniques such as mono and hetero-COSY, NOESY, COLOC as well as H-NMR line broadening effect were utilized for structure elucidation. The separation techniques, struture elucidations and bioassay results will be reported.
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Publication Dates
-
Publication in this collection
24 June 2009 -
Date of issue
1991
