Abstract
For the first time in Brazil it was investigated the occurrence of IgM anti-PGL-1 in the sera of household contacts of leprozy patients using the ELISA methodology. The sera of the multipatients. It was observed a high subclinical infection incidence among household contacts (19.4%). The percentage of leprosy development was 5% (1/21) among the seropositive contact group. This finding suggests that serology could be useful as prognostic test, but for better definition is necessary to tet a population from endemic area for long period time.
ELISA; IgM anti-PGL-1; household contacts
IgM immunoglobulins reacting with the phenolic glycolipid-1 antigen from Mycobacterium leprae in sera of leprosy patients and their contacts
M. H. F. Saad1
M. A. Medeiros1
M. E. N. Gallo1
P. P. Gontijo2
L. S. Fonseca2
Instituto Oswaldo Cruz, Departamento de Medicina Tropical, Laboratório de Hanseníase, Rio de Janeiro, Brasil
Universidade Federal do Rio de Janeiro, Instituto de Microbiologia, Laboratório de Micobactérias, Rio de Janeiro, Brasil
For the first time in Brazil it was investigated the occurrence of IgM anti-PGL-1 in the sera of household contacts of leprozy patients using the ELISA methodology. The sera of the multipatients. It was observed a high subclinical infection incidence among household contacts (19.4%). The percentage of leprosy development was 5% (1/21) among the seropositive contact group. This finding suggests that serology could be useful as prognostic test, but for better definition is necessary to tet a population from endemic area for long period time.
Full text available only in PDF format.
Texto completo disponível apenas em PDF.
Publication Dates
-
Publication in this collection
15 June 2009 -
Date of issue
June 1990
