Abstract
Aqueous extracts of seven species used in Brazilian popular medicine (Achyrocline satureoides, Iodina rhombifolia, Desmodium incanum, Baccharis anomala, Tibouchina asperior, Luehea divaricata, Maytenus ilicifolia) were screened to the presence of mutagenic activity in the Ames test (Salmonella/microsome). Positive results were obtained for A. satureoides, B anomala and L. divaricata with microsomal activation. As shown elsewhere (Vargas et al., 1990) the metabolites of A. satureoides extract also show the capacity to induce prophage and/or SOS response in microscreen phage induction assay and SOS spot chromotest.
Ames test; flovonoids; tannins; plant extracts; Achyrocline satureoides; Luehea divaricata; Baccharis anomala
Genotoxicity of plant extracts
Vera M. F. Vargas1
Régis R. Guidobono1
João A. P. Henriques2
Secretaria da Saúde do Meio Ambiente, Departamento do Meio Ambiente, Porto Alegre, Brasil
UFRGS, Instituto de Biociências, Departamento de Fisiologia, Porto Alegre, Brasil
Aqueous extracts of seven species used in Brazilian popular medicine (Achyrocline satureoides, Iodina rhombifolia, Desmodium incanum, Baccharis anomala, Tibouchina asperior, Luehea divaricata, Maytenus ilicifolia) were screened to the presence of mutagenic activity in the Ames test (Salmonella/microsome). Positive results were obtained for A. satureoides, B anomala and L. divaricata with microsomal activation. As shown elsewhere (Vargas et al., 1990) the metabolites of A. satureoides extract also show the capacity to induce prophage and/or SOS response in microscreen phage induction assay and SOS spot chromotest.
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Publication Dates
-
Publication in this collection
24 June 2009 -
Date of issue
1991
