Bailleux, 2011 |
RCT |
|
|
Average recovery time (days) |
CG |
|
|
Total population: 2.31 (1.99-2.73) |
AB |
|
<2 months: 2.64 (2.25-3.08) |
Hospitalization |
|
≥2 months: 2.01 (1.65-2.44) |
n=496 (238<2 months+258≥2 months) |
|
VHR+2.34 (1.99-2.99) |
289 positive RSV |
CG: Nasal aspiration |
Hypoxemia: 2.73 (2.31-3.33) |
216 cases of hypoxemia |
EG: EFI+PC |
EG |
|
|
Total population: 2.02 (1.98-2.40) |
|
|
<2 months: 2.47 (1.98-3.31) |
|
|
≥2 months: 2.00 (1.51-2.25) |
|
|
VHR+2.33 (1.96-2.92) |
|
|
Hypoxemia: 2.47 (2.02-3.22) |
Barbié, 2008 |
RCT |
Severe AVB |
|
|
|
Outpatient clinic |
|
Silverman's score (breathing difficulty): 3 or 4 (moderate), 5 or 6 (intense) and 7 or 8 (very intense) |
Silverman's score: |
12 babies (7 ♂ + 5 ♀) |
GAN: Nasopharyngeal Aspiration |
SpO2 (%) |
GAN: T0<T1 (p=0.029) |
Age from 29 days to 15 months |
GDRR: RRC |
Reassessment of the clinical picture after the technique (T0) and 5 min later (T5) |
GDRR: T0=T1 |
(average 5.4 months) |
|
|
GAN>GDRR (p=0.002) |
GAN: 7 children |
|
|
|
GDRR: 5 children |
|
|
|
Bernard-Narbonne, 2003 |
Clinical trial without control group |
|
|
|
SpO2
|
|
|
|
T0: 94.5±3.8; |
|
|
|
T1: 95.5±9.9 |
|
|
SpO2 (%) |
T2: 98±5.3 (p<0.05) |
|
|
Transcutaneous capnia (TcPCO2)(mmHg) |
T3: 97.5±10.5(p<0.05) |
|
|
Inspiratory tidal volume (VTI)(ml) |
VTI |
AB |
|
Expiratory tidal volume (VTE)(ml) |
T0: 55.4±16 |
Hospitalization |
EFI |
T0: before tracheal aspiration |
T1: 59.6±17 |
57 infants hospitalized in the resuscitation service, ventilated. |
Duration: 5-10 min depending on the infant's tolerance |
T1: after tracheal aspiration |
T2: 66.3±19(p<0.05) |
|
|
T2: after 1 RR session + tracheal aspiration |
T3: 63.6±20(p<0.05) |
|
|
T3: 1 hour after RR |
VTE: |
|
|
|
T0: 53.15±16 |
|
|
|
T1: 59.1±17 |
|
|
|
T2: 66.1±20(p<0.05) |
|
|
|
T3: 62.3±21(p<0.05) |
Bohe, 2005 |
RCT |
|
|
|
EG |
|
|
|
Clinical score |
32 patients |
|
|
on admission: 5.56±1.96 |
Hospitalization |
|
|
after discharge: 3.25±1.27 |
21♂ + 11♀ |
|
Clinical breathing difficulty score |
Average hospital stay: 4.00±2 |
Average age: 84.8 days |
CG: Nasopharyngeal aspirations |
Severity score based on HR, respiratory, auscultation, and use of accessory muscles (0 to 12 points) |
CG |
Average length of stay: 3.9 days |
EG: Same as control group + DP + Percussion + Vibrations |
Length of hospital stay (days) |
Clinical score on admission: 5.75±1.61 |
25 with VHS+ |
|
Moments: admission and after discharge |
Score after discharge: 3.12±1.15 |
CG=16 |
|
|
Average hospital stay: 3.87 ± 1.3 |
EG=16 |
|
|
Clinical score at admission (p=0.77) |
|
|
|
Score after discharge (p=0.76) |
|
|
|
Average hospital stay (p=0.84) |
Carroll, 2016 |
Retrospective OBS |
|
|
|
Time in the ICU |
|
|
BCH=48 (28-150) |
|
|
CCMC=104 (51-231) |
|
|
MFCH=52 (27-108) |
|
|
YNHCH=66 (36-105) |
|
|
Hospitalization time |
|
|
BCH=145 (98-239) |
|
|
CCMC=186 (118-358) |
AVB |
|
MFCH=151 (90-205) |
ICU |
|
YNHCH=118 (69-202) |
184 (57%) ♂ + 139 (43%)♀ |
|
Intubated: |
Age=68 days |
Time in the ICU (hours) |
BCH 20% |
Hospitals |
Hospitalization time (hours) |
CCMC 44% |
BCH |
Use of: |
MFCH 13% |
Age=67 (39-146) days |
- Albuterol (76%) |
YNHCH 19% |
35 (50%) |
- RR |
Average of all hospitals: |
CCMC |
- Hypertonic saline solution |
Time in the ICU=5.3±8.5 days |
Age=60 (34-118) days |
- High-flow nasal cannula |
76% Albuterol |
56 (54%) ♂ |
- Non-invasive ventilation |
26% Intubated |
MFCH |
- Intrapulmonary percurssive ventilation |
Variations between hospitals: |
Age=73 (31-230) days |
- Ipratropium |
- Albuterol (p=0.002) |
44 (62%) ♂ |
- Systemic corticosteroids. |
- RR (p<0.001) |
YNHCH |
- Inhaled corticosteroids |
- Hypertonic saline solution (p<0.001) |
Age=49 (63%)♂ |
|
- High-flow nasal cannula (p<0.001) |
88 (36-302) days |
|
- Non-invasive ventilation (p<0.001) |
|
|
- Intrapulmonary percurssive ventilation (p<0.001) |
|
|
- Ipratropium (p<0.001) |
|
|
- Systemic corticosteroids (p<0.001) |
|
|
- Inhaled corticosteroids (p=0.01) |
|
|
Time in the ICU increased with: |
|
|
Invasive mechanical ventilation (p<0.001) |
|
|
Inhaled corticosteroid (p=0.0006) |
|
|
Intrapulmonary percurssive ventilation (p<0.001) |
|
|
RR (p=0.0005) |
Castro, 2011 |
EXP without CG |
|
|
Use of oxygen therapy |
|
|
|
Adventitious sounds (medium frequency crackles, high frequency crackles, WH, snoring) |
Adventitious noises |
|
|
Retractions: |
81.4% changed (2.1% worse+13.4% better) (p=0.001) |
|
RR Session: with 10 minutes of each technique: |
Nasal flutter |
Medium frequency crackles |
AB |
-DP |
Intercostal |
15.27% changed (14.4% worse+22.8% better) (p=0.017) |
Hospitalization |
-EFA |
Subdiaphragmatic |
WH |
29 children |
-Percussion |
Sternal |
32.9% changed (12.7% worse+16.5% better) (p=0.010) |
13♂ + 16♀ |
-Vibration |
SpO2 (%) |
Retractions: |
4.6±3 months |
-Nasotracheal aspiration |
Downes' Score: Severity: Mild (1-3), Moderate (4-7), Severe (8-14) |
21.6% changed (8.2% worse+26.8% better) (p=0.001) |
|
|
Moments: |
Downes' score |
|
|
Before RR (Pre) |
20% changed (4.1% worse+21.6% better) (p=0.001) |
|
|
15 to 45 min afterwards (Post) |
|
Conesa-Segura, 2019 |
RCT |
AVB |
|
|
ABBS: |
Hospitalization and ICU |
|
ABBS (mild 0-4, moderate 5-0, severe 10-13) with: |
CG (PS/PR=−7%) |
CG: |
|
WH (0-4) |
EG (PS/PR=−46%) (p=0.01) |
12 (38%) ♀ |
|
Breathing effort (0-3) |
CG < EG (p=0.001) |
2.8 (1.8-5.1) months |
|
Ratio Ins/Exp (0-2) |
CG (P2/PS=−26%) (p=0.001) |
20 with O2
|
CG: |
HR (0-2) |
EG (P2/PS=−108%) (p=0.001) |
48 (0-90) hours of O2
|
Hypertonic saline mist |
RR (cycles/min) |
CG<EG (p=0.001) |
ABBS=6 (31 mild, 56 moderate and 13 severe) |
Nasopharyngeal aspiration |
SpO2 (%) |
CG (AM/PR=−1552%) (p=0.001) |
EG: |
EG: |
Moments: |
EG (AM/PR=−440%) (p=0.001) |
19 (49%) ♀ |
CG + PSE + PC + RRC |
Pre session (PR) |
CG<EG (p=0.002) |
3.3 (1.8-7.0) months |
|
10 minutes post session (PS) |
Average time for ABBS<2: |
23 with O2
|
|
2 hours after session (P2) |
CG (4.4)>EG (2.6) (p<0.0001) |
24 (0-72) hours of O2
|
|
Medical discharge (AM) |
WH, Respiratory Effort and Insp/Exp Ratio: |
ABBS=5 (35 mild, 59 moderate and 3 severe) |
|
|
EG (AM-PR)>CG (AM-PR) (p<0.05) |
Evenou, 2017 |
Prospective OBS |
AVB |
Two daily sessions with EFI |
|
|
Outpatient clinic |
|
|
1st session: n=163: |
|
|
89 ♂ + 74 ♀ |
|
Wang's score (median) |
0-6 months: 89 |
Wang score |
1st session: Pre=5; Post=4 |
6-12 months: 55 |
Moments: Pre and Post sessions |
2nd session: Pre=3; Post=2 |
>12 months: 19 |
|
1st session Pre > 2nd session Post |
2nd session: n=160 |
|
(p <0.0001) |
0-6 months: 87 |
|
|
6-12 months: 54 |
|
|
>12 months: 19 |
|
|
Gajdos, 2010 |
RCT |
AVB |
|
|
|
Hospitalization |
|
|
|
CG: |
|
|
|
141 (56,4%) ♂, |
|
|
|
2.0 (1.3-4.0) months |
|
|
|
39.1±1.65 Pregnancy |
|
|
|
69 in a tobacco environment |
|
|
|
100 with eczema or atopic |
|
|
|
37 in kindergarten |
|
|
|
36 used bronchodilators and 34 used corticosteroids before randomization |
|
|
|
222 with eating difficulties |
|
|
|
3.0 with respiratory symptoms |
Session: 3× a day, 10-15min |
Days of hospitalization |
Adverse effects during the session: |
110 (44.2%) SpO2
|
Oxygen Therapy + Enteral Feeding + Bronchodilators + Corticosteroids |
Adverse effects during the session |
Vomiting CG (1) vs EG (10) (p<0.005) |
31 with atelectasis, 152 with RSV |
CG: nasal suction |
Effects 30 days later |
Respiratory instability CG (3) vs EG (16) (p<0.002) |
37.2 ±0.7°C |
EG: EFI + TA |
|
|
EG: |
|
|
|
134 (54.5%) ♂ |
|
|
|
2.1 (1.3-3.8) months |
|
|
|
39.1±1.67 Pregnancy |
|
|
|
69 in a tobacco environment |
|
|
|
97 with eczema or atopic |
|
|
|
29 in kindergarten |
|
|
|
47 used bronchodilators and 25 used corticosteroids before randomization |
|
|
|
207 with eating difficulties |
|
|
|
3.0 with respiratory symptoms |
|
|
|
18 with atelectasis, 137 with RSV |
|
|
|
37.2±0.6°C |
|
|
|
Ginderdeuren, 2017 |
RCT |
Mild and moderate bronchiolitis |
|
|
CG-B: |
Hospitalization |
|
|
Days of hospitalization: 4.5±1.9 |
CG-B (Control with Bouncing): |
|
|
Wang: |
18♀ +13♂; 160±143 days |
|
|
(T0-T20): 0.2±0.3 |
6.4±2.5 (kg) |
|
|
(T0-T80): 0.5±0.4 |
23 (74%) with VSR; 20 to O2
|
|
|
GAAD: |
2.0±0.8 coryza symptoms |
|
|
Days of hospitalization: 3.6±1.4 |
12±6 time admission and inclusion (hours) |
|
|
Wang: |
5.3±0.9 Wang |
|
Days of hospitalization |
(T0-T20): 0.5±0.5 |
GAAD (assisted autogenic drainage): |
|
Wang's score (0 to 12) |
(T0-T80): 0.8±0.6 |
15♀ +16♂; 121±118 months |
20min/day session |
SpO2 (%) |
GIPV: |
6.2±2.4 (kg) |
CG-B: PC every 5min if there is no spontaneous cough + sitting on a pilates ball, with support, without anterior flexion of the spine, promoting vertical detachments of about 4 to 6cm in amplitude + 3 inhalations of 10min/day |
RR (ppm) |
Days of hospitalization: 3.5±1.3 |
22 (71%) with RSV; 23 to O2
|
GAAD: CG-B + PSE |
Moments: |
Wang: |
2.0±0.8 coryza symptoms |
GIPV: CG-B + 4 5-min cycles of intrapulmonary ventilation at 100 to 300 cycles/min and with 6 to 10 mbar, applied by a mask |
T0: pre-treatment |
(T0-T20): 0.7±0.5 |
14±5 admission and inclusion time (hours) |
|
T20:– 20min after treatment |
(T0-T80): 0.9 ± 0.5 |
5.3±1.2 Wang |
|
T80: 1 hour after T20 |
p-value: |
GIPV (intrapulmonary percussive ventilation): |
|
|
CG-B – GAAD |
16♀+15♂; 135±132 months |
|
|
Days of hospitalization: 0.05 |
6.6 ± 2.2 (kg) |
|
|
Wang: (T0-T20): 0.04, (T0-T80): 0.03 |
23 (74%) with RSV; 18 to O2
|
|
|
CG-B – GIPV |
2.0±0.8 coryza symptoms |
|
|
Days of hospitalization: 0.03 |
15±6 time admission and inclusion (hours) |
|
|
Wang: (T0-T20): <0.01, (T0-T80): <0.01 |
5.5±0.9 Wang |
|
|
GAAD – GIPV |
|
|
|
Wang: (T0-T20): 0.03 |
Gomes, 2012 |
RCT |
AVB |
|
|
Pre/Post |
Hospitalization and ICU |
|
|
2 hours |
Age: 4.08±3.12 months |
|
Wheezing (WH) |
G1: |
G1: |
|
Investigate the primary outcome (CS) |
CS 7.0 (5-11)/4.0(2-7) (p<0.05) |
6♀ + 4♂ |
|
RR (bpm) |
WH 1.0 (0-3)/0(0-1) (p<0.05) |
days: 126.1±125.8 |
|
Retractions (RE) |
RE 2.0 (2-3)/1.0(0-2) (p<0.05) |
Wang's Score: 7.0 (5.0-11) |
|
GenC (general conditions)(min-max) |
G2: |
5.896±2.473 kg |
G1: PSE+RRC |
Intra-Friedman Test |
CS 7.5 (3-10)/5.5(1-7) (p<0.05) |
G2: |
G2: modified DP + expiratory compression + vibration + percussion |
SpO2 (%) |
48 hours: |
3♀ +7♂ |
G3: upper airway aspiration |
Moments: |
G1: |
days: 157.5±99.26 |
|
G1 and G2: |
CS 5.5 (1-7)/3.0(1-5) (p<0.05) |
Wang's score: 7.5 (3.0-10) |
|
Admission |
RE 2.0 (2-3)/1.0(0-2) (p<0.05) |
7.317±1.987 kg |
|
2 hours, 48 and 72 hours after admission |
G2: |
G3: |
|
1 hour before discharge |
CS 4.0 (1-7)/2.0(1-6) (p<0.05) |
5♀ + 5♂ |
|
G3: |
RE 2.0 (2-3)/1.0(0-2) (p<0.05) |
days: 102.1±56.16 |
|
Admission |
72 hours: |
Wang's score: 7.5 (4.0-11) |
|
|
G1: |
5.822±1.029 kg |
|
|
CS 2.0 (0-6)/1.0(0-4) (p<0.05) |
Gomes, 2016 |
RCT |
AVB |
|
|
|
Hospitalization and ICU |
|
|
|
GA (aspiration): |
|
|
|
48.4♂, 4.78±2.98 months |
|
Evaluation |
No significant differences between groups pre session HR: |
Weight: 6.89±2.03 kg |
|
HR (ppm) |
M1: GD<GA at 10 min (p=0.002) and at 30 min (p=0.02) |
0.33±1.34 percentile |
|
RR (bpm) |
M2: GD<GA at 10 min (p=0.038) and at 30 min (p=0.02) |
Birth weight: 3.20±0.57 kg |
1 session |
SpO2 (%) |
Adverse effects (GA vs GD): |
First episode: 68% |
Saline solution at 0.9% |
Adverse effects |
nosebleeds: 28 vs 1 |
SpO2: 95.3±3.7% |
GA: nasal aspiration |
Signs and respiratory distress |
vomiting: 11 vs 7 |
RR 51.7±11.3 cycles/min |
GD: RRC |
Clinical severity score (HR, RR, chest retractions, presence of wheezing, cyanosis and auscultation) |
retractions: 100% vs 84.6% |
DG (clearance): |
|
Moments: |
Moderate severity score (GA vs GD) |
51.6♂, 4.80±2.92 months |
|
Pre: 10 and 30 min after |
retractions (100% vs 84.6%) (p<0.05) |
Weight: 6.70±1.87 kg |
|
M1: early morning |
nosebleeds (44.8% vs 0%) (p<0.05) |
Percentile 0.08±1.27( |
|
M2: early afternoon |
High severity score (GA vs GD) |
Birth weight: 3.21±0.63 kg |
|
M3: night |
nosebleeds (63.6% vs 8.3%) (p<0.05) |
First episode: 72.0% |
|
|
|
RR: 51.6±11.0 cycles/min |
|
|
|
Gonçalves, 2014 |
Cross-sectional OBS |
|
Pulmonary re-expansion maneuvers, manual vibration and postural drainage |
|
RR: |
AVB |
Evaluation: |
Pre (62.1±14) <P3 (66.6±11) (p<0.05) |
Hospitalization |
HR (bpm) |
P6 (63.1±11)>P3 (p<0.05) |
30 neonates |
SpO2 (%) |
P9 (60.7±12)<P3 (p<0.05) |
66.6% ♂ |
RR (ppm) |
SpO2
|
3.4±1.63 months |
Moments: |
Pre (94.9±1.5) <P3 (95.2±1.3) (p<0.05) |
3 with antibiotics |
before treatment (pre) |
P6 (63.1±11)>Pre (p<0.05) |
|
post treatment at 3 (P3), 6 (P6) and 9 (P9) min |
P9 (97.3±0.5)>P3 (p<0.05) |
González-Bellido, 2020 |
RCT |
AVB (light and moderate) |
|
|
|
Outpatient clinic |
|
|
PRE |
G1 (airway clearance technique): |
|
Evaluation: |
No significant differences between groups |
n=44 |
|
Wang's score |
PRE-POST 20 |
17 (38.6%) ♀ |
|
RR (cycles/min) |
Wang's score |
7.5±2.7 months |
1 session only |
HR (ppm) |
G1 and G2: F (2.46.811)=6.09 (p=0.004) |
8.1±1.5 kg |
G1: PSE 20min + PC |
SpO2 (%) |
GACT (0.14±0.46) vs GHFCWC (0.28±0.54) (n2=0.007) |
68.9±7.8 cm |
Medication use: 33 |
Mucus (dry volume) (ml) |
RR |
95.3±2.3% SpO2
|
Bronchodilator: 38 |
Adverse effects: |
G1 and G2: F (2.46.938)=6.0584 (p=0.004) |
48.6±8.0 RR |
G2: PSE SmartVest (12Hz frequency and 2-4cm H2O pressure) 15 min |
Petechiae; |
G1 (27.89±1.93) vs G2 (28.11±2.40) (n2=0.007) |
G2 (high frequency wall compression): |
Medication use: 39 |
Tachycardia |
HR |
n=47 |
No: 8 (17.0) |
Vomiting |
G1 and G2: F (2.46.571)=5.943 (p=0.005) |
15 (31.9%) ♀ |
Bronchodilator: 2 |
Moments: |
G1 (111.0±13.0) vs G2 (116.6±20.0) (n2=0.006) |
8.2±2.4 months |
|
Pre (admission) |
Mucus: G1(19)>G2(30)(p<0.001) |
8.2±1.2 kg |
|
After 10 min |
PRE-POST 10-POST 20 |
69.7±6.6 cm |
|
After 20 min |
Wang's score |
95.4±2.0% SpO2
|
|
|
G1 (54.5 to 9.1%) vs G2 (61.7 to 23.4%) (p=0.009) |
45.5±6.6 RR |
|
|
|
Postiaux, 2006 |
EXP without CG |
|
|
|
CS (n=19): |
|
|
|
Before: |
|
|
|
1st day: 4.3±2 |
|
|
|
2nd day: 3.7±1.8 |
|
|
|
Last day: 2.1±1.3 |
|
|
|
After RR: |
|
|
|
1st day: 2.1±0.8 |
|
|
|
2nd day: 1.8±1.1 |
|
|
|
Last day: 0.9±0.6 (p<0.001) |
|
|
|
SpO2 (n=18): |
AVB |
|
|
Before: |
Hospitalization |
|
|
1st day: 96.2±2.2 |
19 infants: |
|
CS: score from 0 to 3 for each variable, with increasing severity receiving an increasingly higher score. |
2nd day: 96.8±2.4 |
10 ♂ + 9 ♀ |
Daily sessions of 20/30 min (average number of 20 maneuvers applied) |
SpO2 (%) |
Last day: 97.1±1.4 |
7.75±6.6 months |
Techniques: PSE + PC |
HR (ppm) |
After RR: |
32% history of bronchiolitis |
Positioning: DD, head elevation (35º) |
Previous episodes of bronchiolitis (AB) |
1st day: 97.67±1.57 |
26% history of prematurity |
|
Assessment on the 1st, 2nd and last day of session (57 sessions): |
2nd day: 98.28±1.56 |
47% positive radiological signs |
|
before and after 15 min |
Last day: 98.67±1.27 (p<0.001) |
|
|
|
HR (n=16): |
|
|
|
Before RR: |
|
|
|
1st day: 149.4±17.4 |
|
|
|
2nd day: 148.7±17.4 |
|
|
|
Last day: 145.1±16.4 |
|
|
|
After RR: |
|
|
|
1st day: 142.2±16.4 |
|
|
|
2nd day: 138.7±14.4 |
|
|
|
Last day: 134.4±13.1 (p<0.001) |
|
|
|
Average number of sessions (NS): 3.8±1.7 |
|
|
|
A daytime effect is observed in CS (p<0.028), and session effect differs in D1 and JD for AB in CS (p=0.020) and SpO2 (p<0.039). |
Postiaux, 2011 |
RCT |
|
|
|
CG: |
|
|
|
Days of hospitalization: 6.3±2.0 |
|
|
|
T150 <T0: (4.6 vs 5.0, p=0.008) |
|
|
|
T150<T0 (1.1 vs 1.2, p=0.02) |
AVB |
|
|
GCPT: |
Hospitalization |
CG: |
Before each session (T0): |
Days of hospitalization: 5.3±1.8 |
CG (n=8): |
27 sessions |
Wang; |
T30: (3.6 vs 4.3, p=0.001) |
4♀ + 4♂ |
3.3 sessions/patient |
SpO2; |
T150: (3.7 vs 4.3, p=0.002) |
4.2±3.1 months |
Nebulization with 3ml albuterol in hypertonic saline solution for 8 to 10 minutes |
HR (T0) |
SoB: |
6.0±3.2 Wang |
GNMF |
Shortness of breath (SoB) |
T30<T0 (0.8 vs 1.3, p=0.001) |
GNMF (n=12): |
31 sessions |
After the session: |
T150<T0 (0.9 vs 1.3, p=0.001) |
2♀ + 10♂ |
2.5 sessions/patient |
30min (T30) |
CG vs GCPT: |
3.9±2.4 months |
Nebulization followed by 10 to 15 minutes of PSE and PC |
120min (T150) |
T30: |
5.5 ± 2.9 Wang |
|
|
RR (p=0.001) |
|
|
|
HR (p<0.001) |
|
|
|
T30 vs T0: |
|
|
|
Wang: (p=0.004) |
|
|
|
SoB: (p=0.001) |
|
|
|
HR: (p=0.2) |
Pupin, 2009 |
RCT |
|
|
|
GAD, GDP and CG without significant differences in T1 |
|
|
|
GAD: |
|
|
|
HR |
|
|
|
T1 55.59±10.12, T2 54.19±8.88, |
|
|
|
T3 50.26±8.65, T4 47.89±8.54 |
|
|
|
T1 vs T3 (p=0.0171) |
AVB |
|
|
T2 vs T3 (p=0.0016) |
Outpatient clinic |
|
|
T2 vs T4 (p=0.0137) |
EFI and RRC Group (GAD) |
|
|
RR |
18♂ + 9♀ |
|
|
T1 147.67±17.75, T2 151.89±16.19, |
4.59±2.75 months |
|
|
T3 144.00±17.35, T4 146.78±18.97 |
7 comorbidity |
|
|
T2 vs T3 (p=0.0023) |
6 premature |
|
|
T2 vs T4 (p=0.0066) |
13 oxygen support |
Positioning: bench press with headboard elevation |
HR (ppm) |
GDP: |
DP Group (GDP) |
GAD: EFI + RRC |
RR (cycles/min) |
HR |
15♂ + 12♀ |
Repeated up to a maximum of 40 compressions. |
SpO2 (%) |
T1 55.11±11.30, T2 54.85±9.84, |
4.19±2.22 months |
GDP: Vibration + –PC + DP |
T1: before the procedure |
T3 51.22±8.67, T4 49.11±10.81 |
5 comorbidity |
10min |
T2: 10min after |
T1 vs T3 (p=0.0171) |
8 premature |
Untreated CG: manual chest contact |
T3: 30min after |
T2 vs T3 (p=0.0016) |
10 oxygen support |
10min |
T4: 60min fater |
T2 vs T4 (p=0.0137) |
Control group (CG) |
|
|
RR |
15♂ + 11♀ |
|
|
T1 155.11±21.46, T2 156.15±24.55, |
4.78±2.98 meses |
|
|
T3 147.81±16.85, T4 147.11±21.50 |
7 comorbidity |
|
|
T1 vs T4 (p=0.0066) |
4 premature |
|
|
T2 vs T3 (p=0.0126) |
15 with oxygen support |
|
|
CG: |
|
|
|
HR |
|
|
|
T1 56.37±10.06, T2 56.37±9.68, |
|
|
|
T3 54.41±10.17, T4 55.00±8.66 |
|
|
|
T1 vs T3 (p=0.0171) |
|
|
|
T2 vs T3 (p=0.0016) |
|
|
|
T2 vs T4 (p=0.0137) |
Remondini, 2014 |
RCT |
|
|
|
G1: |
AVB |
G1 and G2: bronchodilators and DP |
|
Location: Ward 39 (81%) + ICU 9 |
Hospitalization and ICU |
G1: |
|
Antibiotics: 48 (100%) |
G1: |
puncture |
Location (ward or ICU) |
SpO2: |
14 (29.2%) ♀ + 34 (70.8%) ♂ |
tracheal aspiration |
SpO2 (%) |
<92%: 6 (0) vs 2 (10) vs 5 (60) (p=0.307) |
5.47 months |
Antibiotics: 31 (64.6%) no |
Severity of Lower Respiratory Tract Infection (LRTI) (1 to 17), where <4 is considered mild |
>92%: 42 (0) vs 46 (10) vs 43 (60) (p=0.307) |
39 ICU + 9 hospitalization |
Corticosteroids: 29 (60.4%) no |
Moments: |
LRTI: 5.02 (0) vs 3.06 (10) vs 3.13 (60) (p<0.001) |
SpO2<92%: 6 and ≥92:42 |
G2: |
Before (0) |
G2: |
G2: |
expiratory flow acceleration |
10min after session (10) |
Location: Ward 34 (97%) + ICU 1 |
7 (20.0%) ♀ + 28 (80.0%) ♂ |
tracheal aspiration. |
60min after session (60) |
Antibiotics: 35 (100%) |
6.28 months |
Antibiotic: 19 (54.3%) no |
|
SpO2: |
34 ICU + 1 hospitalization |
Corticosteroids: 13 (37.1%) no |
|
<92%: 7 (0) vs 3 (10) vs 3 (60) (p=0.234) |
SpO2<92: 7 and ≥92:28 |
|
|
>92%: 28 (0) vs 32 (10) vs 32 (60) (p=0.234) |
|
|
|
LRTI: 5.8 (0) vs 3.6 (10) vs. (660) (p<0.001) |
Rochat, 2012 |
RCT |
|
|
|
EG: |
|
|
|
Clinical score: 0.73 (0.91) |
|
|
|
Respiratory score: 9.5 (3.6) |
AVB |
|
|
RR: 53.2 (12.7) |
Hospitalization |
Sessions two times per day |
|
SpO2: 91.9 (4.5) |
EG: |
CG: |
-Clinical score (feeding, vomiting, sleep quality) |
pH: 7.37 (0.06) |
27♂ + 23♀ |
- rhinopharyngeal suction after administration of saline solution |
-Respiratory score (RR, SpO2, presence and severity of retractions, adventitious respiratory sounds, presence of vesicular murmur, chest distention) |
PCO2: 5.73 (1.72) |
110 (95) days |
-oxygen to reach SpO2≥92% |
-RR (cycles/min) |
Bicarbonates: 23.1 (2.5) |
37 at first episode of bronchiolitis |
-fractionated meals |
-SpO2 (%) |
CG: |
37 with RSV ELISA |
-nasal drops (xylometazoline) |
-pH of capillary blood |
Clinical score: 0.73 (0.96) |
1 with another type of virus |
-antibiotics in cases of infection |
-capillary PCO2 (kPa) |
Respiratory score: 9.5 (3.6) |
CG: |
EG: |
-Bicarbonates (mmol/l) |
SpO2: 92.4 (4.8) |
28♂ + 21♀ |
-Same as the control group |
Daily clinical assessments before physiotherapy sessions (in the EG) |
pH: 7.37 (0.05) |
108 (86) days |
-PSE |
|
PCO2: 6.11 (1.30) |
42 at first episode of bronchiolitis |
-EFA |
|
Bicarbonates: 24.3 (2.1) |
37 with RSV ELISA |
-PC |
|
Clinical score: |
1 with another type of virus |
|
|
p=0.37 |
|
|
|
Respiratory score: |
|
|
|
p=0.044 |
Sánchez, 2004 |
Prospective OBS |
AVB |
|
|
|
Hospitalization |
|
|
|
n=223 of 2 hospitals |
|
|
|
HUC: n=93 |
-supplemental oxygen |
|
HUC vs HRS |
56% ♂ + 44% ♀ |
-common adrenaline |
|
Age: 6.6 vs 2.5 (p<0.001) |
6.6 months |
-salbutamol nebulization |
Length of stay (days) |
Hospital days: 3 vs 4 (p<0.018) |
26.9% with chronic respiratory pathology |
-systemic corticosteroid |
Difference in treatments in different centers (%) |
-common adrenaline: 44% vs 81% (p < 0.0001) |
HSR: n=130 |
-antibiotics |
|
-salbutamol nebulization: 90.3% vs 31.5% (p<0.0001) |
54% ♂ + 46% ♀ |
-RR |
|
-RR: 54% vs 86% (p<0.0001) |
2.5 ± 0.2 months |
|
|
|
2.3% with chronic respiratory pathology |
|
|
|
Sánchez-Bayle, 2012 |
RCT |
AVB |
|
|
|
Hospitalization |
10min sessions, 2× a day |
|
|
CG: |
CG: |
|
|
41♀ + 59♂ |
Placebo maneuvers (postural changes) |
|
|
2.48±1.57 months |
Initial medication: |
|
|
80% with respiratory stress |
-Adrenaline (54% of the sample) |
|
Hospitalization days: |
90% with exams |
-Salbutamol (27%) |
|
EG (4.56±2.07) vs CG (4.54±1.72) |
67% with RSV |
-Ipratropium bromide (5%) |
Hospitalization days |
Hours of oxygen therapy: |
37±1 ºC |
-Antibiotics (37%) |
Hours of oxygen therapy |
GR (49.98±37.1) vs CG (53.53±38.87) (p=0.042). |
95±4% SpO2
|
-Adrenaline (50%) |
Final medication (% of sample) |
Final medication: |
EG: |
EG: |
|
-Adrenaline: EG (50%) vs CG (54%) |
55♀ + 81♂ |
PSE + Vibration + PC |
|
-Salbutamol: EG (29.41%) vs CG (27%) |
2.61±1.53 months |
Initial medication: |
|
-Ipratropium bromide: EG (5.14%) vs CG (5%) |
85% with respiratory stress |
-Adrenaline (50% of the sample) |
|
-Antibiotics: EG (38.97%) vs CG (37%) |
88% with exams |
-Salbutamol (29%) |
|
|
67% with RSV |
-Ipratropium bromide (5%) |
|
|
37±1ºC |
-Antibiotics (39%) |
|
|
95±3% SpO2
|
-Adrenaline (54%) |
|
|
Sebban, 2017 |
Prospective OBS |
AVB |
|
|
|
Outpatient clinic |
|
Stratified Wang: |
Wang of 4 [2-6] before and 2 [0-3] after RR (p < 0.01). |
19 (6♀ + 13♂) |
1 physiotherapy session (2 hours and 30 minutes) consisting of techniques: |
<4: class 1: benign bronchiolitis (BB) |
BB: Before (31.6%) and after RR (94.7%) (p<0.0001) |
Age (months) |
RRC + Flow demodulation maneuver practice + PC |
<9: class 2: moderate bronchiolitis (MB) |
MB: before (63.2%) and after RR (5.3%) (p<0.0001) |
From 1 to 3: 8 (42.1%) |
Other treatments received: Bronchodilator, Corticotherapy, Antibiotics |
<12: class 3: severe bronchiolitis related to hospitalization decision (SB) |
SB: before (5.3%) and after RR (0%) (p<0.001) |
From 3 to 6: 7 (36.8%) |
|
Hospitalization |
Hospitalization before RR: 6 |
From 6 to 9: 3 (15.8%) |
|
Before and after (RR) |
Hospitalization after RR: 0 |
From 9 to 12: 1 (5.3%) |
|
|
|
Webb, 1985 |
RCT |
Acute viral bronchiolitis |
|
|
|
Hospitalization |
CG: without RR |
|
CG vs EG |
90 infants (CG=46; EG=44) |
EG: with RR |
Clinical score (maximum score: 30) |
admission (46): 12 vs (44): 10 |
54♂ + 36♀ |
-Cupped hand percussion (3min) |
HR, RR, hyperinflation, use of accessory muscles, recession, rhinitis, wheezing, coughing, crackling and snoring |
day 1 (45): 10 vs (42): 7 |
4 – 6 months |
-5 postural drainages |
On admission, 1-5 days later |
day 2 (39): 8 vs (38): 7 |
69% RSV positive |
-assisted coughing |
|
day 3 (31): 6 vs (28): 7 |
36% family history of atopy |
-oropharyngeal suction (2× daily) |
|
day 4 (21): 6 vs (16): 4 |
66% with smokers at home |
|
|
day 5 (18): 5 vs (11): 6 |