Erratum notice for: “NOP14 inhibits melanoma proliferation and metastasis by regulating Wnt/β-catenin signaling pathway” [Braz J Med Biol Res 2019;52(1):7952]

Jingrong Li^1,2, Ruihua Fang², Jianqin Wang³, and Liehua Deng¹

¹Department of Dermatology, The First Affiliated Hospital of Jinan University, Guangzhou, China

²Department of Dermatology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou, China

³Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, China

Correspondence: Liehua Deng: <[e-mail]>

Erratum for: Braz J Med Biol Res | doi: 10.1590/1414-431X20187952.

The authors notified the Editors of the Brazilian Journal of Medical and Biological Research that there are errors in Table 1 (titles of columns 3 and 4) and that the name of one cell line in the text and in Figures 2, 3, 4, and 5 is incorrect (‘SK-ML110’) in the published article.

The correct cell line in all citations should be ‘SK-MEL-1’ and the correct Table 1 is shown below.

Table 1
Correlation between nucleolar protein 14 (NOP14) protein levels and clinicopathological characteristics of patients with melanoma.

Characteristic	n	NOP14 protein levels		P-value
		High expression (++, +++)	Low expression (-, +)
Age (years)				0.427
<60	21	8	13
≥60	19	5	14
Gender				0.919
Male	18	6	12
Female	22	7	15
Tumor thickness (mm)				0.002
<1	14	9	5
≥1	26	4	22
Site				0.427
Sun-exposed	21	8	13
Sun-protected	19	5	14
Lymph node metastasis				0.010
No	11	7	4
Yes	29	6	23

• Statistical analyses were carried out with the chi-squared test. Bold type indicates statistical significance (P<0.05).

The correct Figures 2, 3, 4, and 5 are as follows:

Figure 2
Effect of nucleolar protein 14 (NOP14) overexpression on melanoma cell proliferation. NOP14 mRNA levels (A) and protein levels (B) in melanoma cell lines transfected with NOP14 overexpression and empty vectors. C and D, Cell proliferation analysis of melanoma cells after transfection of NOP14 overexpression and empty vectors. Data are reported as means±SD. **P<0.01 vs empty vector (ANOVA).

Figure 3
Apoptosis and cell cycle analysis of melanoma cells transfected with nucleolar protein 14 (NOP14) overexpression or empty vector. A and B, Apoptosis analysis of melanoma cells. C and D, Cell cycle analysis of melanoma cells. Data are reported as means±SD. **P<0.01 vs empty vector (t-test).

Figure 4
Migratory ability and invasiveness of melanoma cells determined by transwell assay. NOP14: nucleolar protein 14. Scale bar: 50 μm. Data are reported as means±SD. **P<0.01 vs empty vector (t-test).

Figure 5
Expression level of Wnt3a, β-catenin, and GSK-3β in melanoma cells. A to C, Relative expression and D, protein levels of Wnt3a, β-catenin, and GSK-3β in melanoma cells transfected with nucleolar protein 14 (NOP14) overexpression and empty vectors. Data are reported as means±SD. *P<0.05, **P<0.01 vs empty vector (ANOVA).

Publication Dates

• Publication in this collection
  04 Feb 2022
• Date of issue
  2022