Dismielinizações primárias no sistema nervoso central

Aidar, Orlando

doi:10.1590/S0004-282X1952000100003

Resumo

Diffuse sclerosis, neuromyelitis optica, multiple sclerosis, subacute combined degeneration and acute disseminated encephalomyelitis are briefly described from the anatomical point of view, especially with reference to their variations and to those of their interlocking aspects that point to a unitary concept of their pathogeny. Their features of similarity are compared to the changes described in cases of experimental allergic encephalomyelitis (Ferraro) produced in laboratory animals. Illustrations stress some of the features that are common to those diseases, either in their "typical" or "atypical" forms.

Orlando Aidar

Assistente de Anatomia: Secções de Neuranatomia (Dep. de Anatomia: Prof. R. Locchi) e Neuropatologia (Dep. de Apatomia Patológica: Prof. L. Cunha Motta) da Fac. Med. da Univ. de São Paulo

SUMMARY

Diffuse sclerosis, neuromyelitis optica, multiple sclerosis, subacute combined degeneration and acute disseminated encephalomyelitis are briefly described from the anatomical point of view, especially with reference to their variations and to those of their interlocking aspects that point to a unitary concept of their pathogeny. Their features of similarity are compared to the changes described in cases of experimental allergic encephalomyelitis (Ferraro) produced in laboratory animals.

Illustrations stress some of the features that are common to those diseases, either in their "typical" or "atypical" forms.

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BIBLIOGRAFIA

1. Alvord, E. C. e Stevenson, L. D. - Experimental production of encephalomyelitis in guinea pigs. Kes. Publ. Ass. Nerv. a. Ment. Dis., 28:99-112, 1950.

2. Ferraro, A. - a) Primary demyelinating processes of the central nervous system. Arch. Neurol, a. Psychiat., 37:1100-1160, 1937. b) Pathology, of demyelinating diseases as an allergic reaction of the brain. Arch. Neurol, a. Psychiat., 52:443-483, 1944.

3. Ferraro, A. e Cazzullo, C. L. - Encefalomielite allergica sperinientale e tentafivi di prevenzione della stessa. Sist. Nerv., 2(6):413-419, 1950.

4. Finley, K. H. - The pathology and pathogenesis of encephalomyelitis associated with vaccination and the exanthemas. Res. Publ. Assoc. Nerv. a. Ment. Dis., 28:341-356, 1950.

5. Kabat, E. A., Wolf, A. e Bezer, A. E. - Experimental studies on acute disseminated encephalomyelitis in rh.ez.us monkey. Res. Publ. Assoc. Nerv. a. Ment. Dis., 28:113-132, 1950.

6. Kolb, L. C. - The relationship of the demyelinating diseases to allergic encephalomyelitis. Medicine, 29(2):99-121, 1950.

7. Porta, V. - Malattie demielinizzanti del sistema nervoso. Sist. Nerv., 1(3): 53-67. 1949.

Trabalho apresentado no Departamento de Neuro-Psiquiatria da Associação Paulista de Medicina, em 8 agôsto 1951

Departamento de Anatomia da Fac. Med. da Univ. de São Paulo.

1. Alvord, E. C. e Stevenson, L. D. - Experimental production of encephalomyelitis in guinea pigs. Kes. Publ. Ass. Nerv. a. Ment. Dis., 28:99-112, 1950.
2. Ferraro, A. - a) Primary demyelinating processes of the central nervous system. Arch. Neurol, a. Psychiat., 37:1100-1160, 1937.
b) Pathology, of demyelinating diseases as an allergic reaction of the brain. Arch. Neurol, a. Psychiat., 52:443-483, 1944.
3. Ferraro, A. e Cazzullo, C. L. - Encefalomielite allergica sperinientale e tentafivi di prevenzione della stessa. Sist. Nerv., 2(6):413-419, 1950.
4. Finley, K. H. - The pathology and pathogenesis of encephalomyelitis associated with vaccination and the exanthemas. Res. Publ. Assoc. Nerv. a. Ment. Dis., 28:341-356, 1950.
5. Kabat, E. A., Wolf, A. e Bezer, A. E. - Experimental studies on acute disseminated encephalomyelitis in rh.ez.us monkey. Res. Publ. Assoc. Nerv. a. Ment. Dis., 28:113-132, 1950.
6. Kolb, L. C. - The relationship of the demyelinating diseases to allergic encephalomyelitis. Medicine, 29(2):99-121, 1950.
7. Porta, V. - Malattie demielinizzanti del sistema nervoso. Sist. Nerv., 1(3): 53-67. 1949.