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Study of rat's tracheal allograft viability: the role for omentoplasty with imunossupression

The surgery of trachea has so many problems with grafts viability that recent advances did not promote satisfactory results in tracheal replacement surgery. Peculiar aspects of its circulation and cicatrization Larries problems in surgery. Our aim is to show the value of extraperitonial fat to promote tracheal grafts viability of used 20 tracheal segments of rats Fisher 344 that were implanted in the omentum (10) and in the subcutaneous fat (10). The animals were sacrificed after 20 days to evaluate the viability of tracheal grafts. All animals underment imunossupression with ciclosporin and corticosteroids. Tracheal grafts into the omentum were viable in all rats while the protector effects of extraperitonial fat were uneffective (p<0,05). Our conclusion was that tracheal grafts were not be able to viability in the extraperitonial fat.

Tracheal transplantation in rats; Omentoplasty; Experimental tracheal surgery


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