SUMMARY
Bone marrow transplantation (BMT) has been the treatment of choice for many severe hematologic diseases. The most important complication in the allogeneic transplantation is the graft-vs-host disease (GVHD), that occurs in 50-70% of the cases. Approximately 60% of the transplanted patients who developed GVHD, showed ocular damage, and keratoconjuntivitis sicca was the most common. In this study, thirty-four patients showed dry eye and from these, 27 (79,4%) patients developed GVHD, in agreement with the elevate correlation between dry eye and GVHD. After the iniciation of the conventional therapy, 04 patients developed persistent difuse keractitis and one, bilateral periferic ulcers. The results of this study, indicate the need of obligatory ophthalmologic accompaniment of the patients who underwent BMT.
Key Words:
Bone marrow transplantation; Dry eye and graft-versus-host disease