Primary dural lymphoma: a rare subtype of primary central nervous system lymphoma (PCNSL)

Reis, Fabiano; Schwingel, Ricardo; Queiroz, Luciano de Souza; Zanardi, Verônica de Araújo

doi:10.1590/S0004-282X2011000200025

IMAGES IN NEUROLOGY

Primary dural lymphoma: a rare subtype of primary central nervous system lymphoma (PCNSL)

Linfoma primário dural: um raro subtipo de linfoma primário de sistema nervoso central (LPSNC)

Fabiano Reis^I; Ricardo Schwingel^II; Luciano de Souza Queiroz^III; Verônica de Araújo Zanardi^I

^IMD, PhD, Department of Radiology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^IIMedical Student, Department of Pathology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^IIIMD, PhD, Department of Pathology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^{Correspondence} Correspondence: Fabiano Reis Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Departamento de Radiologia Rua Tessália Vieira de Camargo 126, Caixa Postal 6111, 13083-887 Campinas SP - Brasil E-mail: fabianoreis2@gmail.com

A 56-year-old female with left VI nerve palsy. Diagnostic imaging demonstrated a left cavernous sinus lesion, with a pattern which may be associated to meningioma, lymphoma, inflammatory pseudotumor, tuberculosis or sarcoidosis (Fig 1).

Histological analysis confirmed the diagnosis of marginal zone B-cell lymphoma. Signal intensity and marked enhancement are due to dense cellularity (with high nucleus/cytoplasm ratios) and absence of necrosis (Fig 2).

Primary dural lymphoma is a rare form of PCNSL. It arises from dura mater, usually being a low-grade marginal zone lymphoma, while other types of PCNSL are usually high grade large B-cell lymphomas^1-3.

Received 11 September 2010

Received in final form 15 October 2010

Accepted 25 October 2010

Support: Fapesp

1. Abdullah S, Morgensztern D, Rosado MF, Lossos IS. Primary lymphoblastic B-cell lymphoma of the cranial dura mater: a case report and review of the literature. Leuk Lymphoma 2005;46:1651-1657.
2. Kiewe P, Dallenbach FE, Fischer L, et al. Isolated B-cell lymphoproliferative disorder at the dura mater with B-cell chronic lymphocytic leukemia immunophenotype. Clin Lymphoma Myeloma 2007;7:594-596.
3. Sanjeevi A, Krishnan J, Bailey PR, Catlett J. Extranodal marginal zone B-cell lymphoma of MALT type involving the cavernous sinus. Leuk Lymphoma 2001; 42:1133-1137.

Correspondence:

Fabiano Reis

Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Departamento de Radiologia

Rua Tessália Vieira de Camargo 126,

Caixa Postal 6111, 13083-887 Campinas SP - Brasil

E-mail:

fabianoreis2@gmail.com

Publication Dates

Publication in this collection
26 Apr 2011
Date of issue
Apr 2011

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Abdullah S, Morgensztern D, Rosado MF, Lossos IS. Primary lymphoblastic B-cell lymphoma of the cranial dura mater: a case report and review of the literature. Leuk Lymphoma 2005;46:1651-1657.

[2] 2. Kiewe P, Dallenbach FE, Fischer L, et al. Isolated B-cell lymphoproliferative disorder at the dura mater with B-cell chronic lymphocytic leukemia immunophenotype. Clin Lymphoma Myeloma 2007;7:594-596.

[3] 3. Sanjeevi A, Krishnan J, Bailey PR, Catlett J. Extranodal marginal zone B-cell lymphoma of MALT type involving the cavernous sinus. Leuk Lymphoma 2001; 42:1133-1137.