DESNUTRIÇÃO PROTEICO-ENERGÉTICA EM RATOS Respostas dos animais desnutridos à privação proteica total

Mattos, Leda Ulson

doi:10.1590/0080-6234197901300100019

Resumos

A autora estuda a resposta dos modelos experimentais que mimetizam o Kwashiorkor-marasmático e o marasmo à privação protéica total, usando como parâmetros o teor de nitrogênio do fígado e do pâncreas e de lipídeos totais no fígado.

The author studies the effect of nutritional protein deprivation on experimental models of marasmatic-kwashiorkor and marasmus in rats. The parameters used were quantity of nitrogen in liver and pancreas, and liver lipides.

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REFERÊNCIAS BIBLIOGRÁFICAS

¹ ALBANESE, D. H. A., ed. — New methods of nutritional biochcnlstry. New York, Academic Press 1963. vol. 1, p. 84.
² BARJA, I. et alii — Effect of spacing protein intake on nitrogen balance in normal children. Amer. J. clin. Nutr., New York, 25(5): 506-11, 1972.
³ BEGHIN, I. — Desnutrição protéico-calórica: considerações sobre sua epidemiología. Rev. Bras. Med., Rio de Janeiro, 29(6): 278-83, 1972.
⁴ BEST, H. C. et alii. — Effects of dietary protein, lipotropics factors, and realimentation on total hepatic lipids and their distribution. Brit. Med. J., 1 (4928): 1439-44, June 1955.
⁵ COHN, C. — Feeding frequency and body composition. Ann. N.Y. Acad. Sci., New York, 110: 395-409, 1963.
⁶ COHN, C. Feeding paterns and some aspects os cholesterol metabolism. Fed. Proc, Washington, 23: 76-81, 1964.
⁷ COHN, C. & JOSEPH, D. — Feeding frequency and lipogenesis in undernutrition. Canad. J. Physiol. Pharmacol., Ottawa, 45: 609-12, 1967.
⁸ DEO, M. G. et alii — Experimental protein deficiency. Arch. Path., Chicago, 80: 14-23, 1963.
⁹ FABRY, P. et alii — Lipogenesis in rats adapted to intermitent starvation or continous underfeeding. Experientia, Basel, 18: 555-6, 1962.
¹⁰ FABRY, P. et alii — Energy metabolism and growth in rats adapted to intermitent starvation. Brit. J. Nutr., London, 17: 295-301, 1963.
¹¹ FOLCH, J. et alii — A simple method for the isolation of total lipides from animals tissues. J. biol. Chem., Baltimore, 226: 497-509, 1957.
¹² FOLLIS, R. H. — A Kwashiorkor syndrome observed in monkeys fed maize. Proc. Soc. Exp. Biol., New York, 96:: 523-8, 1957.
¹³ FRYER, J. H. et alii — A caloric paradox. Proc. Nutr. Soc, London, 20: 49, 1961.
¹⁴ GARROW, J. C. et alii — The treatment and prognosis of infantile mal nutrition in Jamaican children. W. Indian med. J., Jamaica, 11(4): 217-27, 1962.
¹⁵ HALAC JUNIOR, E. — Effects of stress on animals fed high protein diets. Amer. J. clin. Nutr., New York, 9: 557-60, 1961.
¹⁶ HALAC JUNIOR, E. Studies of protein reserves — the relation between protein intake and resistance to protein deprivation. Amer. J. clin. Nutr., New York, 11: 574-6, 1962.
¹⁷ HARPER, A. E. — Adaptability and amino-acid requirements. In: HARPER, A. E. Metabolic adaptation and nutrition. Washington, Pan American Health Organization, 1971. (Cientific Publication, 122).
¹⁸ HOLT JUNIOR, L. E. — The concept of proteins stores and its implications in diet. J. Amer. Med. Ass., Chicago, 181: 669-705, 1962.
¹⁹ KIRSCH, R. E. et alii — Animal models and human protein calorie mal nutrition. J. clin. Nutr., Allentown, 21: 1225-8, 1968.
²⁰ MONTGOMERY, R. D. — Changes in the basal metabolic rate of the malnourished infant and their relation to body composition. J. Clin. Invest., New Haven, 41(8): 1653-63, 1962.
²¹ MUKHERJEE, K. L. & SARKAR, N. K. — Liver enzymes in human undernutrition. Brit. J. Nutr., London, 12: 1-7, 1958.
²² PLATT, B. S. et alii — Pathology of acute experimental malnutrition. Proc. Nutr. Soc., London 21: vi, 1962.
²³ SIDRANSKY, H. & BABA, T. — Chemical pathology of acute amino-acid deficiencies. III — Morphologic and biochemical changes in young rats fed valine and lysine devoid diets. J. Nutr., Philadelphia, 70: 463-71, 1960.
²⁴ SIDRANSKY, H. & BABA, T. & CLARK, S. — Chemical pathology of acute amino-acid deficiencies. IV — Influence of carbohydrates intake on the morphologic and biochemical changes in young rats fed threonine or valine devoid diets. Arch. Path., Chicago, 72: 106-17, 1961.
²⁵ SIDRANSKY, H. & BABA, T. & FARBER, E. — Chemical pathology of acute amino-acid deficiencies. I — Morphologic changes in immature rats fed threonine, metionine or histidine devoid diets. Arch. Path., Chicago, 66: 119-34, 1958.
²⁶ STEAD. R. H. & BROCK, J. F. — Experimental protein-calorie malnutrition rapid induction depletion signs in early weaned rats. J. Nutr., Philadelphia, 102: 1357-66, 1972.
²⁷ TEPPERMAN, J. & TEPPERMAN, H. M. — Effects of antecedentes food intake on hepatic lipogenesis. Am. J. Physiol., Washington, 193: 55-64, 1958.
²⁸ TEPPERMAN, J. & TEPPERMAN, H. M. Adaptative hyperlipogenesis. Fed. Proc, Washington, 23: 73-5, 1964.
²⁹ VAUGHAN, O. W. et alii — Influence of prior dietary protein levels on resistance to protein deprivation. Pediatrics., Springfield, 29: 90-6, 1962.
³⁰ WATERLOW, J. C. — Fatty liver disease in infants in the British West Indies. Med. Res. Counc. Spec. Rep. Ser., London, (263): 1948.
³¹ WATERLOW, J. C. & ALLEYNE, J. C. — Má nutrição protéica em crianças: evolução dos conhecimentos nos últimos 10 anos. São Paulo, Nestlé, 1974.
³² WIDDOWSON, E. M. & WHITEHEAD, R. G. — Plasma amino-acid and urinary hidroxy-proline excretions in rats deficient in protein and calorie. Nature, London, 212: 683-6, 1966.
³³ WORLD HEALTH ORGANIZATION. Expert commitee on nutrition: 6th. report. Geneva, 1962. (Technical Report Series, 245).
³⁴ WU, H. & WU, D. Y. — Influence of feeding schedule on nitrogen utilization and excretion. Proc. Soc. Exp. Biol., New York, 74: 78-82, 1950.

Datas de Publicação

Publicação nesta coleção
Abr 1979

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[1] ¹ ALBANESE, D. H. A., ed. — New methods of nutritional biochcnlstry. New York, Academic Press 1963. vol. 1, p. 84.

[2] ² BARJA, I. et alii — Effect of spacing protein intake on nitrogen balance in normal children. Amer. J. clin. Nutr., New York, 25(5): 506-11, 1972.

[3] ³ BEGHIN, I. — Desnutrição protéico-calórica: considerações sobre sua epidemiología. Rev. Bras. Med., Rio de Janeiro, 29(6): 278-83, 1972.

[4] ⁴ BEST, H. C. et alii. — Effects of dietary protein, lipotropics factors, and realimentation on total hepatic lipids and their distribution. Brit. Med. J., 1 (4928): 1439-44, June 1955.

[5] ⁵ COHN, C. — Feeding frequency and body composition. Ann. N.Y. Acad. Sci., New York, 110: 395-409, 1963.

[6] ⁶ COHN, C. Feeding paterns and some aspects os cholesterol metabolism. Fed. Proc, Washington, 23: 76-81, 1964.

[7] ⁷ COHN, C. & JOSEPH, D. — Feeding frequency and lipogenesis in undernutrition. Canad. J. Physiol. Pharmacol., Ottawa, 45: 609-12, 1967.

[8] ⁸ DEO, M. G. et alii — Experimental protein deficiency. Arch. Path., Chicago, 80: 14-23, 1963.

[9] ⁹ FABRY, P. et alii — Lipogenesis in rats adapted to intermitent starvation or continous underfeeding. Experientia, Basel, 18: 555-6, 1962.

[10] ¹⁰ FABRY, P. et alii — Energy metabolism and growth in rats adapted to intermitent starvation. Brit. J. Nutr., London, 17: 295-301, 1963.

[11] ¹¹ FOLCH, J. et alii — A simple method for the isolation of total lipides from animals tissues. J. biol. Chem., Baltimore, 226: 497-509, 1957.

[12] ¹² FOLLIS, R. H. — A Kwashiorkor syndrome observed in monkeys fed maize. Proc. Soc. Exp. Biol., New York, 96:: 523-8, 1957.

[13] ¹³ FRYER, J. H. et alii — A caloric paradox. Proc. Nutr. Soc, London, 20: 49, 1961.

[14] ¹⁴ GARROW, J. C. et alii — The treatment and prognosis of infantile mal nutrition in Jamaican children. W. Indian med. J., Jamaica, 11(4): 217-27, 1962.

[15] ¹⁵ HALAC JUNIOR, E. — Effects of stress on animals fed high protein diets. Amer. J. clin. Nutr., New York, 9: 557-60, 1961.

[16] ¹⁶ HALAC JUNIOR, E. Studies of protein reserves — the relation between protein intake and resistance to protein deprivation. Amer. J. clin. Nutr., New York, 11: 574-6, 1962.

[17] ¹⁷ HARPER, A. E. — Adaptability and amino-acid requirements. In: HARPER, A. E. Metabolic adaptation and nutrition. Washington, Pan American Health Organization, 1971. (Cientific Publication, 122).

[18] ¹⁸ HOLT JUNIOR, L. E. — The concept of proteins stores and its implications in diet. J. Amer. Med. Ass., Chicago, 181: 669-705, 1962.

[19] ¹⁹ KIRSCH, R. E. et alii — Animal models and human protein calorie mal nutrition. J. clin. Nutr., Allentown, 21: 1225-8, 1968.

[20] ²⁰ MONTGOMERY, R. D. — Changes in the basal metabolic rate of the malnourished infant and their relation to body composition. J. Clin. Invest., New Haven, 41(8): 1653-63, 1962.

[21] ²¹ MUKHERJEE, K. L. & SARKAR, N. K. — Liver enzymes in human undernutrition. Brit. J. Nutr., London, 12: 1-7, 1958.

[22] ²² PLATT, B. S. et alii — Pathology of acute experimental malnutrition. Proc. Nutr. Soc., London 21: vi, 1962.

[23] ²³ SIDRANSKY, H. & BABA, T. — Chemical pathology of acute amino-acid deficiencies. III — Morphologic and biochemical changes in young rats fed valine and lysine devoid diets. J. Nutr., Philadelphia, 70: 463-71, 1960.

[24] ²⁴ SIDRANSKY, H. & BABA, T. & CLARK, S. — Chemical pathology of acute amino-acid deficiencies. IV — Influence of carbohydrates intake on the morphologic and biochemical changes in young rats fed threonine or valine devoid diets. Arch. Path., Chicago, 72: 106-17, 1961.

[25] ²⁵ SIDRANSKY, H. & BABA, T. & FARBER, E. — Chemical pathology of acute amino-acid deficiencies. I — Morphologic changes in immature rats fed threonine, metionine or histidine devoid diets. Arch. Path., Chicago, 66: 119-34, 1958.

[26] ²⁶ STEAD. R. H. & BROCK, J. F. — Experimental protein-calorie malnutrition rapid induction depletion signs in early weaned rats. J. Nutr., Philadelphia, 102: 1357-66, 1972.

[27] ²⁷ TEPPERMAN, J. & TEPPERMAN, H. M. — Effects of antecedentes food intake on hepatic lipogenesis. Am. J. Physiol., Washington, 193: 55-64, 1958.

[28] ²⁸ TEPPERMAN, J. & TEPPERMAN, H. M. Adaptative hyperlipogenesis. Fed. Proc, Washington, 23: 73-5, 1964.

[29] ²⁹ VAUGHAN, O. W. et alii — Influence of prior dietary protein levels on resistance to protein deprivation. Pediatrics., Springfield, 29: 90-6, 1962.

[30] ³⁰ WATERLOW, J. C. — Fatty liver disease in infants in the British West Indies. Med. Res. Counc. Spec. Rep. Ser., London, (263): 1948.

[31] ³¹ WATERLOW, J. C. & ALLEYNE, J. C. — Má nutrição protéica em crianças: evolução dos conhecimentos nos últimos 10 anos. São Paulo, Nestlé, 1974.

[32] ³² WIDDOWSON, E. M. & WHITEHEAD, R. G. — Plasma amino-acid and urinary hidroxy-proline excretions in rats deficient in protein and calorie. Nature, London, 212: 683-6, 1966.

[33] ³³ WORLD HEALTH ORGANIZATION. Expert commitee on nutrition: 6th. report. Geneva, 1962. (Technical Report Series, 245).

[34] ³⁴ WU, H. & WU, D. Y. — Influence of feeding schedule on nitrogen utilization and excretion. Proc. Soc. Exp. Biol., New York, 74: 78-82, 1950.

DESNUTRIÇÃO PROTEICO-ENERGÉTICA EM RATOS Respostas dos animais desnutridos à privação proteica total

Protein-calorie malnutrition in rats-response of protein-calorie malnourished rats to a nutritional protein deprivation

Resumos

REFERÊNCIAS BIBLIOGRÁFICAS

Datas de Publicação