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The Challenges of Controlling Arterial Hypertension in the Elderly

Keywords
Hypertension/epidemiology; Aged; Hypertension/prevention and control; Prevalence; Arterial Pressure

This issue of the “Archives” brings the study “Hypertension Prevalence, Treatment and Control in Older Adults in a Brazilian Capital City”, by Souza ALL et al.,11 Sousa ALL, Batista SR, Sousa AS, Pacheco JAS, Vitorino Pv, Pagotto V. Prevalência, tratamento e controle da hipertensão arterial em idosos de uma capital brasileira. Arq Bras Cardiol. 2019; 112(3):271-278. disclosing data about this important cardiovascular risk factor in Goiânia, state of Goiás, Brazil, depicting the situation in our coutry.11 Sousa ALL, Batista SR, Sousa AS, Pacheco JAS, Vitorino Pv, Pagotto V. Prevalência, tratamento e controle da hipertensão arterial em idosos de uma capital brasileira. Arq Bras Cardiol. 2019; 112(3):271-278. In this mini-editorial, we review the epidemiology of arterial hypertension (AH) in Brazil and worldwide.

AH is the leading preventable cause of premature death.22 Lim SS, Vos T, Flaxman AD,Danali G, Shibuya K, Adair-Rohani H, et al., A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2224-60. A report by the US Institute of Medicine considers AH as a neglected disease, because it is often overlooked by the population and underestimated by the medical community.33 Institute of Medicine (US) Committee on Public Health Priorities to Reduce and Control Hypertension. A Population-Based Policy and Systems Change Approach to Prevent and Control Hypertension. Washington (DC): National Academies Press (US); 2010. Although AH is relatively easy to prevent, simple to diagnose and considerably less expensive to treat, it remains one of the most important causes of death.44 Mitka M. IOM urges more attention by physicians, public on "neglected" hypertension. JAMA. 2010;303(14):1354-5. More than 50% of deaths from coronary artery disease and cerebrovascular accidents in the US occur in individuals with AH.55 Ford ES. Trends in mortality from all causes and cardiovascular disease among hypertensive and nonhypertensive adults in the United States. Circulation. 2011; 123(16):1737-44.

A survey concluded that the estimated global prevalence of AH is increasing.66 Mills KT, Bundy JD, Kelly TN,Reed JE, Kearney PM, Reynolds K, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016; 134(6):441-50. Globally, 31.1% of the adult population had AH in 2010. The prevalence of AH is higher in low- and middle-income countries (31.5%) when compared to high-income countries (28.5%).66 Mills KT, Bundy JD, Kelly TN,Reed JE, Kearney PM, Reynolds K, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016; 134(6):441-50. From 2000 to 2010, the AH prevalence in high-income countries decreased by 2.6%, and awareness, treatment and control substantially improved. However, in low- and middle-income countries, there was an increase in prevalence of 7.7%.66 Mills KT, Bundy JD, Kelly TN,Reed JE, Kearney PM, Reynolds K, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016; 134(6):441-50.

However, a more recent analysis showed that the overall prevalence of age-standardized AH was 24.1% in men and 20.1% in women by 2015.77 NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. Lancet. 2017; 389(10064):37-55. The worldwide number of adults with AH increased from 594 million in 1975 to 1.13 billion in 2015, increasing mainly in low- and middle-income countries.77 NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. Lancet. 2017; 389(10064):37-55.

In relation to the elderly population, the International Mobility In Aging Study (IMIAS) showed that the prevalence of AH ranged from 53.4% to 83.5% in five assessed cities: Kingston (Canada), Saint-Hyacinthe (Canada), Tirana (Albania), Manizales (Colombia) and Natal (Brazil).88 Doulougou B, Gomez F, Alvarado B, Guerra RO, Ylli A, Guralnik J, et al. Factors associated with hypertension prevalence, awareness, treatment and control among participants in the International Mobility in Aging Study (IMIAS). J Hum Hypertens. 2016;30(2):112-9. More than 2/3 of the hypertensive participants were aware of the diagnosis (of 67.3% in Saint-Hyacinthe to 85.4% in Tirana), especially among women.88 Doulougou B, Gomez F, Alvarado B, Guerra RO, Ylli A, Guralnik J, et al. Factors associated with hypertension prevalence, awareness, treatment and control among participants in the International Mobility in Aging Study (IMIAS). J Hum Hypertens. 2016;30(2):112-9. Although more than 80% of the patients were receiving treatment, the control rates were low: 37.6% in Manizales; 29.5% in Kingston; 26.5% in Saint-Hyacinthe; 24% in Tirana and 22% in Natal, with the Brazilian city showing the least effective disease control.88 Doulougou B, Gomez F, Alvarado B, Guerra RO, Ylli A, Guralnik J, et al. Factors associated with hypertension prevalence, awareness, treatment and control among participants in the International Mobility in Aging Study (IMIAS). J Hum Hypertens. 2016;30(2):112-9.

Currently, Canada has the world's best rates of AH control, estimated at 68% of the affected population.99 Schiffrin EL, Campbell NR, Feldman RD,Kaczorowski J, Lewanczuck R, Padwal R, et al. Hypertension in Canada: past, present, and future. Ann Glob Health. 2016; 82(2):288-99. That country has achieved a dramatic reduction regarding the lack of diagnosis knowledge (43% in 1991 versus 17% in 2013), with the percentage of patients being treated increasing from 34% to 80% in the same period.99 Schiffrin EL, Campbell NR, Feldman RD,Kaczorowski J, Lewanczuck R, Padwal R, et al. Hypertension in Canada: past, present, and future. Ann Glob Health. 2016; 82(2):288-99.

The US has shown better AH control in women than in men (55.3% versus 38.0% in 2009-2012); as well as among Whites compared to Blacks and Hispanics (41.3% versus 31.1% and 23.6%).1010 National Center for Health Statistics (U.S.). Health, United States, 2013: With Special Feature on Prescription Drugs. Hyattsville, MD: National Center for Health Statistics (US); 2014. In that country, there is a better AH control among the elderly than in young individuals (50.5%, in adults aged 60 to 70 years, versus 34.4% in patients aged 18 to 39 years in 2011-2012).1111 Nwankwo T, Yoon SS, Burt V, Gu Q. Hypertension among adults in the United States: National Health and Nutrition Examination Survey, 2011-2012. NCHS Data Brief. 2013 Oct (133):1-8.,1212 Bromfield SG, Bowling CB, Tanner RM, Peralta CA, Odden MC, Oparil S, et al. Trends in hypertension prevalence, awareness, treatment, and control among US adults 80 years and older, 1988-2010. J Clin Hypertens (Greenwich). 2014; 16(4):270-6. As for the population aged 75 years or older, there was a slight decline in control (46%), which continues to decline from 80 years onward (39.8%).1212 Bromfield SG, Bowling CB, Tanner RM, Peralta CA, Odden MC, Oparil S, et al. Trends in hypertension prevalence, awareness, treatment, and control among US adults 80 years and older, 1988-2010. J Clin Hypertens (Greenwich). 2014; 16(4):270-6.

In Brazil, data from the “Surveillance System for Risk and Protective Factors for Chronic Diseases by Telephone Survey (Vigitel)” (2006 to 2014), indicate that self-reported AH in adults living in capitals ranged from 23% to 25%.1313 VIGITEL Brasil 2014. Vigilância de fatores de risco e proteção para doenças crônicas por inquérito telefônico. [Internet]. Disponível em: http://portalsaude.saude.gov.br/images/pdf/2015/abril/15/PPT-Vigitel-2014-.pdf . Acesso em: 21/12/2018.
http://portalsaude.saude.gov.br/images/p...
,1414 Malachias M, Plavnik FL, Machado CA, Malta D, Scala LCN, Fuchs S. 7th Brazilian Guideline of Arterial Hypertension: Chapter 1 - Concept, Epidemiology and Primary Prevention. Arq Bras Cardiol. 2016; 107(3 Suppl 3):1-6. Among adults aged 60 to 64 years, the prevalence was 44.4%; in those aged 65 to 74 years, 52.7%; and from 75 years onward, 55%.1313 VIGITEL Brasil 2014. Vigilância de fatores de risco e proteção para doenças crônicas por inquérito telefônico. [Internet]. Disponível em: http://portalsaude.saude.gov.br/images/pdf/2015/abril/15/PPT-Vigitel-2014-.pdf . Acesso em: 21/12/2018.
http://portalsaude.saude.gov.br/images/p...
The rates of knowledge (22% to 77%), treatment (11.4% to 77.5%) and control (10.1% to 35.5%) varied widely, depending on the assessed population.1515 Scala LC, Magalhães LB, Machado A. Epidemiologia da hipertensão arterial sistêmica. In: Moreira SM, Paola AV; Sociedade Brasileira de Cardiologia. Livro Texto da Sociedade Brasileira de Cardiologia. 2ª. ed. São Paulo: Manole; 2015. p. 780-5. Data from VIGITEL 2017, related to 2016, showed that 60.9% of adults aged 65 years and older reported the diagnosis of AH in a telephone survey.1616 Brasil. Ministe´rio da Saúde (MS). Secretaria de Vigilância em Saúde. Departamento de Vigilância de Doenças e Agravos não Transmissíveis e Promoção da Saúde. VIGITEL Brazil 2017: surveillance of risk and protective factors for chronic diseases by telephone survey: estimates of Frequency and sociodemographic distribution of risk and protective factors for chronic diseases in the capitals of the 26 Brazilian states and the Federal District in 2017 - Brasília; 2018.[Citado em 218 out 12) Disponível em http://bvsms.saude.gov.br/bvs/publicacoes/vigitel_brasil_2017_vigilancia_fatores_risco.pdf. Acesso em 21/12/2018.
http://bvsms.saude.gov.br/bvs/publicacoe...

The first Brazilian Registry of AH reveals encouraging data, demonstrating a significant improvement in AH control in the country, when considering the population treated in referral centers.1717 Lopes RD, Barroso WKS, Brandão AA, Barbosa EC, Malachias MVB, Gomes MM, et al. First Brazilian Registry of Hypertension. Am Heart J. 2018 Nov; 205:154-7. Based on the population treated in 45 centers distributed throughout all Brazilian regions, with a mean age of 61 years, blood pressure (BP) control was observed below 140/90 mmHg in 59.6% of the patients, considering the stabilization of BP in all visits, and 60.6% when considering the measurements in the one-year follow-up consultation.1717 Lopes RD, Barroso WKS, Brandão AA, Barbosa EC, Malachias MVB, Gomes MM, et al. First Brazilian Registry of Hypertension. Am Heart J. 2018 Nov; 205:154-7. Such rates, however, do not reflect the overall situation of AH control in the country.

In the article by Souza ALL et al.,11 Sousa ALL, Batista SR, Sousa AS, Pacheco JAS, Vitorino Pv, Pagotto V. Prevalência, tratamento e controle da hipertensão arterial em idosos de uma capital brasileira. Arq Bras Cardiol. 2019; 112(3):271-278. published in this issue, the total prevalence of AH in the assessed elderly was 74.9%, being higher among men (78.6%). The treatment rate was 72.6% and the percentage of AH control was 50.8%, being higher among women.11 Sousa ALL, Batista SR, Sousa AS, Pacheco JAS, Vitorino Pv, Pagotto V. Prevalência, tratamento e controle da hipertensão arterial em idosos de uma capital brasileira. Arq Bras Cardiol. 2019; 112(3):271-278. These data show that, although there is still need for improvement, there has been an important increase in the rates of diagnosis, knowledge, treatment and control of AH in our country, especially among the elderly population.

  • Short Editorial related to the article: Hypertension Prevalence, Treatment and Control in Older Adults in a Brazilian Capital City

References

  • 1
    Sousa ALL, Batista SR, Sousa AS, Pacheco JAS, Vitorino Pv, Pagotto V. Prevalência, tratamento e controle da hipertensão arterial em idosos de uma capital brasileira. Arq Bras Cardiol. 2019; 112(3):271-278.
  • 2
    Lim SS, Vos T, Flaxman AD,Danali G, Shibuya K, Adair-Rohani H, et al., A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2224-60.
  • 3
    Institute of Medicine (US) Committee on Public Health Priorities to Reduce and Control Hypertension. A Population-Based Policy and Systems Change Approach to Prevent and Control Hypertension. Washington (DC): National Academies Press (US); 2010.
  • 4
    Mitka M. IOM urges more attention by physicians, public on "neglected" hypertension. JAMA. 2010;303(14):1354-5.
  • 5
    Ford ES. Trends in mortality from all causes and cardiovascular disease among hypertensive and nonhypertensive adults in the United States. Circulation. 2011; 123(16):1737-44.
  • 6
    Mills KT, Bundy JD, Kelly TN,Reed JE, Kearney PM, Reynolds K, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016; 134(6):441-50.
  • 7
    NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. Lancet. 2017; 389(10064):37-55.
  • 8
    Doulougou B, Gomez F, Alvarado B, Guerra RO, Ylli A, Guralnik J, et al. Factors associated with hypertension prevalence, awareness, treatment and control among participants in the International Mobility in Aging Study (IMIAS). J Hum Hypertens. 2016;30(2):112-9.
  • 9
    Schiffrin EL, Campbell NR, Feldman RD,Kaczorowski J, Lewanczuck R, Padwal R, et al. Hypertension in Canada: past, present, and future. Ann Glob Health. 2016; 82(2):288-99.
  • 10
    National Center for Health Statistics (U.S.). Health, United States, 2013: With Special Feature on Prescription Drugs. Hyattsville, MD: National Center for Health Statistics (US); 2014.
  • 11
    Nwankwo T, Yoon SS, Burt V, Gu Q. Hypertension among adults in the United States: National Health and Nutrition Examination Survey, 2011-2012. NCHS Data Brief. 2013 Oct (133):1-8.
  • 12
    Bromfield SG, Bowling CB, Tanner RM, Peralta CA, Odden MC, Oparil S, et al. Trends in hypertension prevalence, awareness, treatment, and control among US adults 80 years and older, 1988-2010. J Clin Hypertens (Greenwich). 2014; 16(4):270-6.
  • 13
    VIGITEL Brasil 2014. Vigilância de fatores de risco e proteção para doenças crônicas por inquérito telefônico. [Internet]. Disponível em: http://portalsaude.saude.gov.br/images/pdf/2015/abril/15/PPT-Vigitel-2014-.pdf . Acesso em: 21/12/2018.
    » http://portalsaude.saude.gov.br/images/pdf/2015/abril/15/PPT-Vigitel-2014-.pdf
  • 14
    Malachias M, Plavnik FL, Machado CA, Malta D, Scala LCN, Fuchs S. 7th Brazilian Guideline of Arterial Hypertension: Chapter 1 - Concept, Epidemiology and Primary Prevention. Arq Bras Cardiol. 2016; 107(3 Suppl 3):1-6.
  • 15
    Scala LC, Magalhães LB, Machado A. Epidemiologia da hipertensão arterial sistêmica. In: Moreira SM, Paola AV; Sociedade Brasileira de Cardiologia. Livro Texto da Sociedade Brasileira de Cardiologia. 2ª. ed. São Paulo: Manole; 2015. p. 780-5.
  • 16
    Brasil. Ministe´rio da Saúde (MS). Secretaria de Vigilância em Saúde. Departamento de Vigilância de Doenças e Agravos não Transmissíveis e Promoção da Saúde. VIGITEL Brazil 2017: surveillance of risk and protective factors for chronic diseases by telephone survey: estimates of Frequency and sociodemographic distribution of risk and protective factors for chronic diseases in the capitals of the 26 Brazilian states and the Federal District in 2017 - Brasília; 2018.[Citado em 218 out 12) Disponível em http://bvsms.saude.gov.br/bvs/publicacoes/vigitel_brasil_2017_vigilancia_fatores_risco.pdf Acesso em 21/12/2018.
    » http://bvsms.saude.gov.br/bvs/publicacoes/vigitel_brasil_2017_vigilancia_fatores_risco.pdf
  • 17
    Lopes RD, Barroso WKS, Brandão AA, Barbosa EC, Malachias MVB, Gomes MM, et al. First Brazilian Registry of Hypertension. Am Heart J. 2018 Nov; 205:154-7.

Publication Dates

  • Publication in this collection
    Mar 2019
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