Achados vídeo-angiográficos da síndrome de Vogt-Koyanag-Harada utilizando o oftalmoscópio de varredura a laser

Monteiro, Mônica F. Cunha

doi:10.5935/0004-2749.19950013

RESUMO

Este estudo utilizou o oftalmoscópio de varredura a laser para realização de vídeo-angiofluoresceinogramas em pacientes com a síndrome de Vogt-Koyanagi-Harada. Através da natureza dinâmica e excelente resolução dos vídeo-angiogramas, foi possível observar minuciosamente os achados angiofluoresceinográficos, como também medir os tempos de enchimento coriocapilar macular, e de circulação retiniana arterial e venosa.

Comparado a um grupo controle, o grupo com a síndrome apresentou um atraso significativo (P=0,02) no tempo de enchimento coriocapilar macular. Este é um novo achado na síndrome de Vogt-Koyanagi-Harada.

Palavras-chave:
Síndrome de Vogt-Koyanagi-Harada; Oftalmoscopia de varredura a laser; Tempo de enchimento coriocapilar macular

SUMMARY

This study utilized the scanning laser ophthalmoscope to perform video-fluoresceinangiograms in patients with the Vogt-Koyanagi-Harada syndrome. Through the dynamic nature and excellent image resolution of the video-angiograms, it was possible to observe the fluoresceinangiographic features in great detail, and also to measure macular choroidal capillary filling time, and retinal arterial and venous circulation times.

Compared to an age-matched control group, the group with the syndrome presented a significant delay (P=0.02) in macular choroidal capillary filling time. This is a new finding in the Vogt-Koyanagi-Harada syndrome.

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REFERÊNCIAS BIBLIOGRÁFICAS

¹
DELORI, F. C.; PARKER, J. S.; MAINSTER, M. A. - Light levels in fundus photography. Vision Res., 20: 1099-1104, 1980.
²
ELSNER, A. E. Scanning Laser Ophthalmoscopy, Tomography, and Visual Function Evaluation. Clin Vision Sci. 7: v-viii., 1992.
³
ELSNER, A. E.; WEITER, J. J.; JALKH, A. E. New Devices for Retinal Imaging and Functional Evaluation. In: FREEMAN, W. R. - Practical Atlas of Retinal Disease and Therapy. New York: Raven Press Ltd.; 1993. p. 19-35.
⁴
WEBB, R. H.; HUGHES, G. W. - Scanning laser ophthalmoscope. IEEE Trans Biomed Eng. BME-28: 488-92, 1981.
⁵
WEBB, R. H.; HUGHES, G. W.; POMERANTZEFF, O. - Flyng spot TV ophthalmoscope. Appl Optics. 19: 2991-7, 1980.
⁶
BELFORT R. Jr.; NISHI, M.; HAYASHI, S.; ABREU, M. T.; PETRILLI, A. M. N.; PLUT, R. C. A. - Vogt-Koyanagi-Harada's Disease in Brazil. Jpn. J. Ophthalmol., 22: 9-35, 1988.
⁷
OHNO, S.; CHAR, D. H.; KIMURA, S. J.; O'CONNOR, R. G. - Vogt-Koyanagi-Harada syndrome. Am. J. Ophthalmol., 83: 735-740, 1977.
⁸
SUGIURA, S. - Vogt-Koyanagi-Harada Disease. Jpn. J. Ophthalmol., 22: 9-35, 1978.
⁹
RAO, N. A.; FORSTER, D. J.; SPALTON, D. J. Vogt-Kayanagi-Harada Syndrome. In: RAO, N. A.; FORSTER, D. J.; AUGSBURGER, J. J. - The Uvea: Uveitis and Intraocular Neoplasms. London: Gower Medical Publishing; 1992. p. 8.13-8.17,.
¹⁰
HAYREH, S. S. - Segmental nature of the choroidal vasculature. B. J. Ophthalmol., 59: 631-649, 1975.
¹¹
HAYREH, S. S. - Submacular Choroidal Vascular Pattern. Albretcht v Graefes klin exp Ophthalmol., 192: 181-196, 1974.
¹²
RICHARD, G. - Choroidal Circulation New York: Thieme Medical Publishers Inc., 1992. p. 33-104.
¹³
FRIEDMAN, A. H. - Uveitis Affecting the Retina and Posterior Segment. In: FREEMAN, W. R. Practical Atlas of Retinal Disease and Therapy. New York: Raven Press. Ltd., 1993. 59-61.
¹⁴
MOORTHY, R. S.; CHONG, L. P.; SMITH, R. E.; RAO, N. A. - Subretinal Neovascular Membranes in Vogt-Koyanagi-Harada Syndrome. Am. J. Ophthalmol. 116: 164-170, 1993.
¹⁵
NUSSENBLATT, R. B. & PALESTINE, A. G. Vogt-Koyanagi-Harada syndrome. In: RYAN, S. J. Retina St. Louis, C. V. Mosby, 1989. p. 723-734.
¹⁶
KAHN, M.; PEPOSE, J. S.; GREEN , W. R.; MILLER, J.; FOOS, R. Y. - Immunocytologic findings in a case of Vogt-Koyanagi-Harada syndrome. Ophthalmology, 100: 1191-8, 1993.
¹⁷
McCLELLAN, K. A.; MacDONALD, M.; HERSEY, P.; BILLSON, F. A. - Vogt-Koyanagi-Harada syndrome -isolation of cloned T cells with specificity for melanocytes and melanoma cells. Australian and New Zealand J. of Ophthalmol. 17: 347-52, 1989.
¹⁸
SAKAMOTO, T.; MURATA, T.; INOMATA, H. - Class II major histocompatibility complex on melanocytes of Vogt-Koyanagi-Harada disease. Arch. Ophthalmol. 109: 1270-4, 1991.

Datas de Publicação

Publicação nesta coleção
Dec 1995

Este é um artigo publicado em acesso aberto (Open Access) sob a licença Creative Commons Attribution, que permite uso, distribuição e reprodução em qualquer meio, sem restrições desde que o trabalho original seja corretamente citado.

[1] ¹
DELORI, F. C.; PARKER, J. S.; MAINSTER, M. A. - Light levels in fundus photography. Vision Res., 20: 1099-1104, 1980.

[2] ²
ELSNER, A. E. Scanning Laser Ophthalmoscopy, Tomography, and Visual Function Evaluation. Clin Vision Sci. 7: v-viii., 1992.

[3] ³
ELSNER, A. E.; WEITER, J. J.; JALKH, A. E. New Devices for Retinal Imaging and Functional Evaluation. In: FREEMAN, W. R. - Practical Atlas of Retinal Disease and Therapy. New York: Raven Press Ltd.; 1993. p. 19-35.

[4] ⁴
WEBB, R. H.; HUGHES, G. W. - Scanning laser ophthalmoscope. IEEE Trans Biomed Eng. BME-28: 488-92, 1981.

[5] ⁵
WEBB, R. H.; HUGHES, G. W.; POMERANTZEFF, O. - Flyng spot TV ophthalmoscope. Appl Optics. 19: 2991-7, 1980.

[6] ⁶
BELFORT R. Jr.; NISHI, M.; HAYASHI, S.; ABREU, M. T.; PETRILLI, A. M. N.; PLUT, R. C. A. - Vogt-Koyanagi-Harada's Disease in Brazil. Jpn. J. Ophthalmol., 22: 9-35, 1988.

[7] ⁷
OHNO, S.; CHAR, D. H.; KIMURA, S. J.; O'CONNOR, R. G. - Vogt-Koyanagi-Harada syndrome. Am. J. Ophthalmol., 83: 735-740, 1977.

[8] ⁸
SUGIURA, S. - Vogt-Koyanagi-Harada Disease. Jpn. J. Ophthalmol., 22: 9-35, 1978.

[9] ⁹
RAO, N. A.; FORSTER, D. J.; SPALTON, D. J. Vogt-Kayanagi-Harada Syndrome. In: RAO, N. A.; FORSTER, D. J.; AUGSBURGER, J. J. - The Uvea: Uveitis and Intraocular Neoplasms. London: Gower Medical Publishing; 1992. p. 8.13-8.17,.

[10] ¹⁰
HAYREH, S. S. - Segmental nature of the choroidal vasculature. B. J. Ophthalmol., 59: 631-649, 1975.

[11] ¹¹
HAYREH, S. S. - Submacular Choroidal Vascular Pattern. Albretcht v Graefes klin exp Ophthalmol., 192: 181-196, 1974.

[12] ¹²
RICHARD, G. - Choroidal Circulation New York: Thieme Medical Publishers Inc., 1992. p. 33-104.

[13] ¹³
FRIEDMAN, A. H. - Uveitis Affecting the Retina and Posterior Segment. In: FREEMAN, W. R. Practical Atlas of Retinal Disease and Therapy. New York: Raven Press. Ltd., 1993. 59-61.

[14] ¹⁴
MOORTHY, R. S.; CHONG, L. P.; SMITH, R. E.; RAO, N. A. - Subretinal Neovascular Membranes in Vogt-Koyanagi-Harada Syndrome. Am. J. Ophthalmol. 116: 164-170, 1993.

[15] ¹⁵
NUSSENBLATT, R. B. & PALESTINE, A. G. Vogt-Koyanagi-Harada syndrome. In: RYAN, S. J. Retina St. Louis, C. V. Mosby, 1989. p. 723-734.

[16] ¹⁶
KAHN, M.; PEPOSE, J. S.; GREEN , W. R.; MILLER, J.; FOOS, R. Y. - Immunocytologic findings in a case of Vogt-Koyanagi-Harada syndrome. Ophthalmology, 100: 1191-8, 1993.

[17] ¹⁷
McCLELLAN, K. A.; MacDONALD, M.; HERSEY, P.; BILLSON, F. A. - Vogt-Koyanagi-Harada syndrome -isolation of cloned T cells with specificity for melanocytes and melanoma cells. Australian and New Zealand J. of Ophthalmol. 17: 347-52, 1989.

[18] ¹⁸
SAKAMOTO, T.; MURATA, T.; INOMATA, H. - Class II major histocompatibility complex on melanocytes of Vogt-Koyanagi-Harada disease. Arch. Ophthalmol. 109: 1270-4, 1991.

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