The objective of this study is to demonstrate the importance of the scientific method since the emergence of modern science and its model of rationality. It is a Philosophical reflection by means of an imaginary approximation of letters between Fracastoro and Descartes, based on bibliographies found in LILACS, SciELO, and the Google search engine. The authors used descriptions by means of letters from a fictional correspondence between Girolamo Fracastoro and René Descartes. The former, from his works Syphilis Sive Morbus Gallicus and De contagione et contagiosis et curatione and the latter with the Speech of the Method, used as a model of modern science and Rules for the Direction of the Spirit. The approach supposed by the authors between Fracastoro and Descartes reveals to us that the method proposed by Descartes, if it had been used by the Italian scientist, would have opened new possibilities of visibility and projection of his works.
History; Philosophy; Health