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Association between multimorbidity, intensive care unit admission, and death in patients with COVID-19 in Brazil: a cross-section study, 2020

ABSTRACT

BACKGROUND:

Multimorbidity can influence intensive care unit (ICU) admissions and deaths due to coronavirus disease (COVID-19).

OBJECTIVE:

To analyze the association between multimorbidity, ICU admissions, and deaths due to COVID-19 in Brazil.

DESIGN AND SETTING:

This cross-sectional study was conducted using data from patients with severe acute respiratory syndrome (SARS) due to COVID-19 recorded in the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe) in 2020.

METHODS:

Descriptive and stratified analyses of multimorbidity were performed based on sociodemographic, ventilatory support, and diagnostic variables. Poisson regression was used to estimate the prevalence ratios.

RESULTS:

We identified 671,593 cases of SARS caused by COVID-19, of which 62.4% had at least one morbidity. Multimorbidity was associated with male sex, age 60–70 and ≥ 80 years, brown and black skin color, elementary education and high school, ventilatory support, and altered radiologic exams. Moreover, all regions of the country and altered computed tomography due to COVID-19 or other diseases were associated with death; only the northeast region and higher education were associated with ICU admission.

CONCLUSION:

Our results showed an association between multimorbidity, ICU admission, and death in COVID-19 patients in Brazil.

KEY WORDS (MeSH terms):
Multimorbidity; Morbidity; COVID-19; Hospitalization; Death; Comorbidity

AUTHORS’ KEY WORDS:
Coronavirus deaths in Brazil; COVID-19 prevalence studies; Hierarchical multiple logistic models; Intensive care unit

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