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Microbiological profile of bloodstream infections and antimicrobial resistance patterns at a tertiary referral hospital in Amazon, Brazil

ABSTRACT

Background:

Bloodstream infections (BSI) are a global health issue, leading to high mortality and morbidity among hospitalized patients.

Methods:

A retrospective, observational and descriptive study was conducted by reviewing blood culture records collected from patients with suspected BSI, between January 2017 and December 2019.

Results:

The most frequent antimicrobial resistant (AMR) pathogens were methicillin-resistantStaphylococcus aureus(MRSA) (40%), methicillin-resistantS. epidermidis (MRSE) (9.5%), and extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (35.3%).

Conclusions:

Our findings underscore the importance of continued vigilance and advocate for the rational use of antimicrobial agents.

Keywords:
Antimicrobial resistance; Bloodstream infections; Sepsis; MRSA; ESBL

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