ABSTRACT
Background:
This study aimed to evaluate IgG and IgM levels in COVID-19 recurrence.
Methods:
The serum antibody levels and clinical data from 73 healthcare workers with SARS-CoV-2 divided into seroconverted (n=51) and non-seroconverted (n=22) groups were assessed. The presence of specific anti-nucleocapsid (anti-N) IgM and IgG for SARS-CoV-2 was evaluated. IgG antibodies to the SARS-CoV-2 spike receptor-binding domain were used to confirm non-seroconversion in all negative anti-N.
Results:
Four recurrent cases displayed mild symptoms and were non-seroconverted until the recurrence of symptoms.
Conclusions:
Undetectable anti-nucleocapsid IgM and IgG levels may be correlated with symptomatic COVID-19 recurrence.
Keywords:
COVID-19; SARS-CoV-2; Recurrence; Humoral Reactivity
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