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Short Communication • Rev. Soc. Bras. Med. Trop. 53 • 2020 • https://doi.org/10.1590/0037-8682-0336-2019   copy

In vitro characterization of virulence factors among species of the Candida parapsilosis complex

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

INTRODUCTION:

Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence.

METHODS:

The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex strains.

RESULTS:

Among the studied isolates, 97.7%, 63.2%, and 82.8% exhibited very strong proteinase, esterase, and hemolysin activity, respectively. All the C. parapsilosis complex isolates produced biofilms and presented an average adherence of 96.0 yeasts/100 epithelial cells.

CONCLUSIONS:

Our results show that Candida parapsilosis complex isolates showed different levels of enzyme activity, biofilm production, and adhesion to epithelial cells.

Keywords:
Candida parapsilosis; Virulence factors; Biofilms; Cell adhesion; Hydrolytic enzymes

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