Hypothermia among premature newborns on admission to a neonatal intensive care unit

Carvalho, Janaina Otoni de; Toledo, Luana Vieira; Braga, Luciene Muniz; Krempser, Paula; Pacheco, Zuleyce Maria Lessa; Dutra, Herica Silva

doi:10.1590/1983-1447.2023.20220042.en

Janaina Otoni de Carvalho

conceptualization

data curation

writing – original draft

methodology

resources

Universidade Federal de Juiz de Fora (UFJF), Faculdade de Enfermagem, Programa de Pós-Graduação em Enfermagem. Juiz de Fora, Minas Gerais, Brasil.

http://orcid.org/0000-0002-6869-7305

Luana Vieira Toledo

formal analysis

writing – original draft

writing – review & editing

Universidade Federal de Viçosa (UFV), Departamento de Medicina e Enfermagem. Viçosa, Minas Gerais, Brasil.

http://orcid.org/0000-0001-9527-7325

Luciene Muniz Braga

writing – review & editing

Universidade Federal de Viçosa (UFV), Departamento de Medicina e Enfermagem. Viçosa, Minas Gerais, Brasil.

http://orcid.org/0000-0002-2297-395X

Paula Krempser

writing – review & editing

Universidade Federal de Juiz de Fora (UFJF), Faculdade de Enfermagem, Programa de Pós-Graduação em Enfermagem. Juiz de Fora, Minas Gerais, Brasil.

http://orcid.org/0000-0003-4838-6873

Zuleyce Maria Lessa Pacheco

writing – review & editing

Universidade Federal de Juiz de Fora (UFJF), Faculdade de Enfermagem, Programa de Pós-Graduação em Enfermagem. Juiz de Fora, Minas Gerais, Brasil.

http://orcid.org/0000-0002-9409-8971

Herica Silva Dutra

conceptualization

project administration

formal analysis

writing – original draft

writing – review & editing

methodology

resources

supervision

Universidade Federal de Juiz de Fora (UFJF), Faculdade de Enfermagem, Programa de Pós-Graduação em Enfermagem. Juiz de Fora, Minas Gerais, Brasil.

http://orcid.org/0000-0003-2338-3043

Corresponding author:
Herica Silva Dutra E-mail: herica.dutra@ufjf.br

Associate editor:

Helena Becker Issi

Editor-in-chief:

Maria da Graça Oliveira Crossetti

Authorship contribution:

Conceptualization: Janaina Otoni de Carvalho; Herica Silva Dutra. Data curation: Janaina Otoni de Carvalho. Project management: Herica Silva Dutra. Formal analysis: Luana Vieira Toledo, Herica Silva Dutra. Writing - original draft: Janaina Otoni de Carvalho, Luana Vieira Toledo, Herica Silva Dutra. Writing - review and editing: Luciene Muniz Braga, Paula Krempser, Luana Vieira Toledo, Zuleyce Maria Lessa Pacheco, Herica Silva Dutra Methodology: Janaina Otoni de Carvalho, Herica Silva Dutra. Ressources: Janaina Otoni de Carvalho, Herica Silva Dutra. Supervision: Herica Silva Dutra.

The authors declare that there is no conflict of interest.

Variables	median (Q₁-Q₃)
Vital Signs on admission
Axillary Temperature	36.2 (35.9 - 36.6)
Heart Rate	149.0 (137.0 - 161.0)
Respiratory Rate	46.0 (40.0 - 52.0)
Length of Stay in the NICU	11 (7 - 26)
Gender	n	%
Female	68	44.2
Male	86	55.8
Gestational Age
Extremely preterm (< 28 weeks)	16	10.4
Very preterm (28 to 31 weeks)	28	18.2
Moderate preterm (32 to 33 weeks)	40	26.0
Late preterm (34 to 36 weeks)	70	45.4
Birth Weight
Extremely low weight < 999g	28	18.2
Very low weight 1,000g to 1,499g	35	22.7
Low weight 1,500g to 2,500g	73	47.4
Adequate weight >2,500g	18	11.7
Apgar 1^st minute
0 to 6	80	51.9
7 to 10	74	48.1
Apgar 5^th minute
0 to 6	9	5.8
7 to 10	145	94.2
Origin
Operating Room	86	55.8
Birth Center	40	26.0
Neonatal Intermediate Care Unit	28	18.2
Outcome for Patients
Discharge	130	84.4
Death	24	15.6

Variables	Hypothermia				p-value
Variables	No		Yes		p-value
Vital Signs on admission	median (Q₁-Q₃)
Heart Rate	155.0 (138.0-167.0)		148.0 (136.0160.0)		0.251²
Respiratory Rate	46.0 (41.0-56.0)		45.0(40.0-52.0)		0.937²
Length of Stay in the NICU	10 (7-15.0)		12 (8.0-32.0)		0.203²
Gender	n	%	n	%	0.899¹
Female	22	44.9	46	43.8
Male	27	55.1	59	56.2
Gestational Age
Extremely preterm (< 28 weeks)	2	4.1	14	13.3	0.007^1*
Very preterm (28 to 31 weeks)	6	12.2	22	21.0
Moderate preterm (32 to 33 weeks)	9	18.4	31	29.5
Late preterm (34 to 36 weeks)	32	65.3	38	36.2
Birth Weight
Extremely low weight < 999g	1	2.0	27	25.7	<0.001^1*
Very low weight 1,000g to 1,499g	9	18.4	26	24.8
Low weight 1,500g to 2,500g	27	55.1	46	43.8
Adequate weight >2,500g	12	24.5	6	5.7
Apgar 1^st minute
0 to 6	18	36.7	62	59	0.010^1*
7 to 10	31	63.3	43	41	0.010^1*
Apgar 5^th minute
0 to 6	1	2.0	8	7.6	0.273¹
7 to 10	48	98.0	97	92.4	0.273¹
Origin
Operating Room	25	51.0	61	58.1	0.018^1*
Birth Center	9	18.4	31	29.5
Neonatal Intermediate Care Unit	15	30.6	13	12.4
Outcome for Patients
Discharge	47	95.9	83	79.0	0.008^1*
Death	2	4.1	22	21.0	0.008^1*

Variable	Hypothermia				p-value
Surfactant administration	n	%	n	%
No	43	87.8	63	60.0	0.001¹^*
Yes	6	12.2	42	40.0	0.001¹^*
Ventilatory support
No	16	32.7	17	16.2	0.020¹^*
Yes	33	67.3	88	83.8	0.020¹^*
Bladder catheter
No	49	100	104	99.0	1.000¹
Yes	-	-	1	1.0	1.000¹
Central Peripheral Inserted Catheter
No	48	98.0	90	85.7	0.022¹^*
Yes	1	2.0	15	14.3	0.022¹^*
Oro/nasogastric tube
No	5	10.2	3	2.9	0.111¹
Yes	44	89.8	102	97.1	0.111¹
Umbilical catheter
No	45	91.8	77	73.3	0.010¹^*
Yes	4	8.2	28	26.7	0.010¹^*
Orotracheal intubation
No	40	81.6	62	59.0	0.006¹^*
Yes	9	18.4	43	41.0	0.006¹^*
Peripheral venous access
No	2	4.1	27	25.7	0.001¹^*
Yes	47	95.9	78	74.3	0.001¹^*
Arterial blood sample
No	1	2.0	4	3.8	0.666¹
Yes	48	98.0	100	95.2
Not informed	-	-	1	1.0
Peripheral blood test
No	25	51.0	60	57.1	0.720¹
Yes	15	30.6	28	24.8
Not informed	9	18.4	19	18.1

Variables	B	Wald	OddsRatio	CI- 95%	p-value
Adequate weight	-	14.191	-	-	-
Low weight	1.247	4.835	3.480	1.145-10.574	0.028^*
Very low weight	1.766	7.532	5.845	1.656-20.626	0.006*
Extremely low weight	3.855	11.381	47.211	5.029-443.229	0.001^*
Constant	-0.799	2.420	0.450	-	0.120

[1] Corresponding author:
Herica Silva Dutra E-mail: herica.dutra@ufjf.br

Brasil

Brasil

Hypothermia among premature newborns on admission to a neonatal intensive care unit

Hipotermia entre los recién nacidos prematuros que ingresan en una unidad de cuidados intensivos neonatales

ABSTRACT

Objective:

Methods:

Results:

Conclusion: