The prognosis of patients with juvenile dermatomyositis (JDM) has improved, allowing adolescents and young adults to have an increased chance of sexual activities and pregnancy. From 1983 to 2004, 4,638 patients were followed at the Pediatric Rheumatology Unit of the Pediatric Department of FMUSP, of which 117 (86/74% female) were diagnosed with JDM and 3 of them became pregnant during the follow-up. The first sexual intercourse occurred at 15 years old (case 1) and at 14 years old (cases 2 e 3). The pregnancies, all of them not planned, occurred at 16 years old and 3 months (case 1), 15 years old and 4 months (case 2) and 14 years old and 7 months (case 3). The disease of patient 1 was active when she became pregnant, but she was at remission by the end of the second trimester of gestation, she was given 2 g/kg/month of intravenous immunoglobulin (during the first 5 months) and prednisone (during all the period); she had a full-term pregnancy with a normal birth. Patients 2 and 3 were on disease remission when they became pregnant and their gestations developed with no complications. Patient 2 had a full-term delivery; her newborn was adequate for gestational age and had no complications. Patient 3 had a Cesarean delivery due to low amniotic fluid; her newborn was premature (36 weeks) but adequate for gestational age and with no problems during neonatal period. None of the patients presented disease flare-up after delivery. Precocious sexual activity and pregnancy increase in adolescents with JDM should be considered in the routine clinical follow-up of these patients.
juvenile dermatomyositis; adolescents; sexuality; pregnancy