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Rhinocerebral mucormycose: case presentation and literature review

Fungal sinusitis are divided in two big groups: (1) Invasive form that is subdivided in acute and chronic; (2) Noninvasive form that is subdivided in mycetoma form (fungal ball) and allergic form. The development of one of these forms depends on the immunologic relationship of the fungus to the host, as invasive form occurs in most of the cases in immunocompromised hosts. It is reported a diabetic female, with suspected fungi sinusitis with clinical invasive features at its very beginning displaying high fever and left eye involvement that lead to amaurosis. A left orbital surgical drainage followed by sinusectomy resulted in a nasocutaneous fistula, that stabilized when antifungal treatment was instituted, with no more rinorrhea, fever and periorbital inflammatory signs. As improvement progressed the nasocutaneous fistula was closed under general anesthesia. On histopatology, respiratory epithelium with inflammatory process and septated hyphae was found, that disclosed zygomycosis. After one year of no patient's symptoms, she started to be followed by facial surgeons who did a naso-orbital esthetics surgery with a high patient's satisfaction.

mucormycosis; zygomycosis; rinocerebral mucormycosis; sinusal fungal infections


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