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Extranodal non-Hodgkins lymphomas in Salvador, Brazil: clinical aspects and histopathological classification according to the WHO-2001 guidelines

Extranodal non-Hodgkins lymphomas represent approximately one third of all lymphomas and currently have an incidence higher than nodal lymphomas. Differences in etiology, presentation and outcome of these lymphomas have been reported. However, there are no data in our population. This study was carried out in the Pathological Anatomy Service of Aristides Maltez Hospital in Salvador, Bahia. One hundred and forty-five non-Hodgkins lymphomas cases according to the WHO-2001 classification detected between January 1999 and July 2001 were evaluated. The frequency of extranodal lymphomas was 30.3%. The mean age of the patients was 55.6% years and the male/female ratio was 1:1. The majority of the patients presented with advanced stages, B symptoms, normal LDH, ECOG between o and 2 and IPI between O and 2. Nine patients are still alive in complete remission (22.5%) with a mean follow-up of 23 months. The main extranodal sites were the tonsils followed by the oral cavity, skin and gastrointestinal tract. Diffuse large B-Cell lymphoma was the mains histological subtype, followed by anaplastic large-cell lymphoma. In summary, the mains extranodal site in our study was different from the masority of reports. However our extranodal lymphoma frequency was similar.

Extranodal non-Hodgkin lymphoma; tonsils; histopathology


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