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Anti-Lutheran B in a patient with acute lymphoblastic leukemia

Acute leukemia needs hemotherapeutic support to be successfully treated. The Lutheran B antibody, specifically the high frequency of this antigen in our population, has made it difficult to treat hematological malignancies that need transfusional support, including acute lymphoblastic leukemia. Finding compatible blood is complex and so the authors adopted a conservative treatment strategy. The prescription of epoetin and an individualized chemotherapy protocol may improve results. We describe a case report of a patient with anti-Lutheran B antibody and how difficulties to find compatible blood were solved.

Leukemia; B-cell; acute; Lutheran Blood-Group System; erythropoietin; recombinant; blood group incompatibility; blood transfusion


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