Chagas disease is a systemic infection with a chronic onset transmitted by Trypanosoma cruzi. The last study conducted in Recife, capital of Pernambuco state, was carried out during 1970. At that time a prevalence of 4.4% was found among blood donors of a local hospital. Due to the lack of epidemiology data on T. cruzi infection and as Pernambuco is an endemic region, the present study describes the profile of blood donors who presented reactivity for Chagas disease during the period of 2002 to 2007 in the state's blood bank (Hemope). The profile of unsuitable donors was evaluated according to gender, age and according to the meso-regions of Pernambuco. A prevalence of 0.17% was found for Chagas disease, whereas 6.89% of the rejected blood bags were due to this reactivity. As far as gender is concerned, the reactivity of men was higher than that of women (p<0.0001). Additionally, the age group between 18-30 years was less infected (20.21%). On analyzing the reactivity in each one of the meso-regions of the state, it was found that, in the Metropolitan Region of Recife, the number of inconclusive reaction cases was statistically higher than the number of reactive serology cases (p=0.0440). Thus, epidemiological studies provide important data to indirectly evaluate the risk of blood-borne diseases and allow indirect evaluation of the effectiveness of vectorial control measures in endemic regions.
Chagas disease; serological screening; blood donnors
