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Case reports • Rev. Bras. Hematol. Hemoter. 33 (2) • 2011 • https://doi.org/10.5581/1516-8484.20110036   copy

Disease progression after R-CHOP treatment associated with the loss of CD20 antigen expression

Authorship SCIMAGO INSTITUTIONS RANKINGS

A case of a follicular lymphoma transformed into a CD20+ is described which progressed with the loss of CD20 expression after 8 cycles of R-CHOP. This phenomenon is not a rare event and has shown poor prognosis. Our purposes are to describe this event and suggest biopsy in relapsed or progressive disease.

Lymphoma, Large B-cell, diffuse; Disease progression; Immunotherapy

Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular R. Dr. Diogo de Faria, 775 cj 114, 04037-002 São Paulo/SP/Brasil, Tel. (55 11) 2369-7767/2338-6764 - São Paulo - SP - Brazil
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