Relationship between the ability to walk long distances and to climb up and down stairs with the health-related quality of life of older adults with symptomatic knee osteoarthritis

Almeida, Camila Cadena de; DeSantana, Josimari Melo; Durigan, João Luiz Quagliotti; Azevedo, Patrícia Garcia

doi:10.1590/1981-22562021024.220007.en

Acessibilidade / Reportar erro

Brasil

Revista Brasileira de Geriatria e Gerontologia

Español English

Brasil

Español English

sumário « anterior atual seguinte »

Sumário

Original Articles • Rev. bras. geriatr. gerontol. 24 (5) • 2021 • https://doi.org/10.1590/1981-22562021024.220007.en copy

Relationship between the ability to walk long distances and to climb up and down stairs with the health-related quality of life of older adults with symptomatic knee osteoarthritis

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

Objective

To investigate the relationship between physical capacity and health-related quality of life (HRQoL) in older patients with symptomatic knee osteoarthritis (KOA).

Method

A cross-sectional study was carried out, in which 67 older people (55 women and 12 men) diagnosed with KOA completed the physical function tests: Timed Up and Go (TUG); 30-second Chair Stand Test (30CST); Stair Climb Test (SCT); 40m Fast-Paced Walk Test (40FPWT); and Six-Minute Walk Test (6MWT). HRQoL was measured using the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC). Univariate and multivariate linear regression analyzes were used to explore the relationship between the variables.

Results

Patients were predominantly female, overweight, inactive, non-depressed, with bilateral KOA and in severe pain. In HRQoL, the domains showed low performance compared to healthy individuals. An association was observed between 30CST, SCT, 40FPWT and 6MWT with pain and physical function and an association of 30CTS, 6MWT with stiffness (R² = 0.064 to 0.304, p<0.05). In the multivariate analysis, BMI, sex and bilateral impairment were also considered as independent variables, resulting in significant associations of the 6MWT and BMI with pain (ß[6MWT]=0.121, 95%CI 0.005 to 0.237; ß[BMI]=0.022, 95CI and sex (ß=10.724, 95%CI 2.985 to 18.463) with physical function.

Conclusion

The results suggests positive association between TSDE and physical function and negative associations between physical capacity on 6MWT on pain and stifness.

Keywords
Older Adults; Quality of Life; Osteoarthritis; Knee; Physical Functional Performance

Variables	Total sample	Female (n=55)	Male (n=12)
Age (years)^a	68.8 (5.8)	68.36 (5.69)	70.50 (6.028)
Sex (female)^c	82.1 (55)	-	-
BMI (Kg/m²)^a	30.38 (7.98)	30.60 (8.66)	29.43 (3.99)
Underweight^c	1.5 (1)	0.0 (0)	25.0 (3)
Eutrophic^c	16.9 (11)	15.1 (8)	25.0 (3)
Overweight^c	81.5 (53)	84.9 (45)	66.7 (8)
Joint impairment (bilateral)^c	73.1 (49)	78.2 (43)	50.0 (6)
Physical exercise practice (inactive)^c	79.1 (53)	84.9 (45)	66.7 (8)
Number of medications^a	4.07 (2.2)	4.10 (2.074)	3.91 (2.844)
MMSE (score) ^a	21.4 (5.9)	21.02 (6.317)	23.67 (3.367)
NRS (0-10)^a	7.7 (2.2)	7.83 (2.193)	7.50 (2.431)
GDS (total score)^a	5.04 (3.19)	5.51 (3.090)	2.92 (2.906)
Not depressed^c	62.7 (42)	56.4 (31)	91.7 (11)
Mild depression^c	28.4 (19)	34.5 (19)	0.0 (0)
Severe depression^c	9 (6)	9.1 (5)	8.3 (1)
Physical capacity
TUG (s)^b	13.03 (11.05 – 16.07)	13.06 (11.07 – 16.04)	12.55 (10.45 – 19.54)
30CTS (repetition number)^b	7 (5 – 9)	7 (5 – 8)	8.50 (6.50 – 11.00)
SCT (s)^b	77 (63.05 – 95.05)	81.02 (67.56 – 100.72)	55.32 (42.03 – 76.54)
40FPWT (s)^b	37.07 (32.09 – 43.09)	39.05 (33.55 – 44.52)	30.28 (26.54 – 35.01)
6MWT (m)^b	371.00 (317.00 – 430.00)	365.00 (316.00 – 418.00)	445.00 (410.00 – 524.50)
WOMAC
Pain (0-20)^b	10.00 (7.00 – 13.00)	10.00 (8.00 – 13.50)	8.50 (5.00 – 10.50)
Stiffness (0-8)^b	2.00 (0.00 – 4.00)	3.00 (0.00 – 4.00)	1.50 (0.00 – 2.00)
Physical function (0-68)^b	31.00 (17.00 – 41.00)	33.00 (26.50 – 41.50)	15.00 (9.50 – 22.00)

	WOMAC
Independent variables	Pain		Stiffness		Physical function
Independent variables	r	p	r	p	r	p
30CST	0.254^a	0.038	-	-	0.259^a	0.034
SCT	0.42^a	<0.001	0.252^b	0.04	0.552^a	<0.001
40FPWT	0.329^a	0.007	-	-	0.397^a	0.001
6MWT	0.389^a	0.001	0.279^a	0.022	0.445^a	<0.001

Dependent variable	Independent variable	Univariate regression
Dependent variable	Independent variable	R² (R²_adj)	Beta (CI 95%)	p -value
WOMAC – Pain	TUG	0.014 (-0.015)	-0.010 (-0.197 to 0.176)	0.913
	30CST	0.064 (0.050)	-0.367 (-0.714 to -0.020	0.038
	SCT	0.180 (0.168)	0.064 (0.030 to 0.098)	<0.001
	40FPWT	0.108 (0.094)	0.111 (0.032 to 0.189)	0.007
	6MWT	0.151 (0.138)	-0.019 (-0.031 to -0.008)	0.001
WOMAC- Stiffness	TUG	0.020 (0.005)	0.064 (-0.047 to 0.174)	0.252
	30CST	0.017 (0.002)	-0.113 (-0.326 to 0.100)	0.293
	SCT	0.064 (0.049)	0.023 (0.001 to 0.044)	0.040
	40FPWT	0.035 (0.021)	0.038 (-0.011 to 0.087)	0.127
	6MWT	0.078 (0.064)	-0.008 (-0.015 to -0.001)	0.022
WOMAC- Physical function	TUG	0.001 (-0.014)	0.079 (-0.557 to 0.715)	0.806
	30CST	0.067 (0.053)	-1.279 (-2.461 to -0.097)	0.034
	SCT	0.304 (0.293)	0.284 (0.178 to 0.391)	<0.001
	40FPWT	0.158 (0.145)	0.455 (0.195 to 0.716)	0.001
	6MWT	0.198 (0.186)	-0.076 (-0.114 to -0.038)	<0.001

Dependent variable	Independent variables	Multivariate Regression
Dependent variable	Independent variables	R² (R²_adj)	'Cohen's f² (Effect Size) (power)	Beta (CI 95%)	Individual Significance (p-value)
WOMAC– Pain	30CST	0.247 (0.223)	0.32 (99%)	-	-
	SCT			-	-
	40FPWT			-	-
	6MWT			-0.022 (-0.033 to -0.010)	<0.001
	Female Sex			-	-
	BMI			0.121 (0.005 to 0.237)	0.041
	GDS			-	-
WOMAC- Stiffness	SCT	0.141 (0.113)	0.16 (83%)	-	-
	6MWT			-0.009 (-0.016 to -0.001)	0.021
	Female Sex			-	-
	BMI			0.076 (0.000 to 0.151)	0.049
WOMAC- Physical function	30CST	0.395 (0.376)	0.65 (99%)	-	-
	SCT			0.229 (0.121 to 0.336)	<0.001
	40FPWT			-	-
	6MWT			-	-
	Female Sex			10.724 (2.985 to 18.463)	0.007
	BMI			-	-
	Bilateral KOA			-	-
	GDS			-	-

Universidade do Estado do Rio Janeiro Rua São Francisco Xavier, 524 - Bloco F, 20559-900 Rio de Janeiro - RJ Brasil, Tel.: (55 21) 2334-0168 - Rio de Janeiro - RJ - Brazil
E-mail: revistabgg@gmail.com

Acompanhe os números deste periódico no seu leitor de RSS

[1] Correspondence Camila Cadena de Almeida cadenacamila@gmail.com