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Experimental model of degloving injury in hind limb

Degloving injuries may be a challenge when it comes to deciding the surgical approach to be used. Repositioning of the flap and suturing is faster and more straightforward, but often leads to total or partial loss of the avulsed flap. Skin flap deffating and grafting of the detached flap have the disadvantages of resulting in poor aesthetic appearance and being less protective, but they have been the most widely used due to the higher rate of graft take. Pharmacological agents with vascular properties that enhance the viability of the reattached flap could be beneficial to patients with degloving injuries. In a way to test drugs with vascular properties is necessary to develop an experimental model. This paper presents an animal model of degloving injury in the hind limb of rats. Rats were subjected to the proposed degloving model of hind limb, resulting in a reverse flow flap. The flap was then repositioned and sutured.

Wounds and injuries; Lower extremity; Skin; Necrosis; Animal models


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