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Late prognosis in young patients with stable coronary disease: 10-year follow-up of percutaneous coronary intervention

BACKGROUND: The late prognostic implications of stable coronary artery disease (CAD) in young patients are currently unknown. The objective of this study was to evaluate the prognosis of young adult patients diagnosed with stable CAD, treated by percutaneous coronary intervention (PCI) and followed-up for 10 years. METHODS: The study population consisted of young patients (age below the 10th percentile) of a group of 1,394 consecutive patients treated for stable CAD using the percutaneous approach. Patient characteristics were collected prospectively. After the procedure outpatient follow-up was performed, including the analysis of the electronic medical records and telephone contact, whenever required. The primary outcome was overall mortality and the secondary outcome was cardiovascular mortality. RESULTS: One hundred and forty patients were selected, with mean age of 43.7 ± 4 years (ranging from 26 to 48 years) and were predominantly males (76.4%). Diabetes mellitus was present in approximately one fifth of patients and half of them had a previous myocardial infarction. Patients were followed for an average of 94.6 ± 36.2 months and the overall mortality after 10 years was 6%, with cardiac mortality of 5.3%. All of the patients who died had a successful index procedure and only one of the cases did not have a previous myocardial infarction. CONCLUSIONS: In our clinical practice, young patients with chronic CAD treated by PCI demonstrated a good late prognosis.

Angioplasty; Coronary disease; Age groups; Prognosis


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