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Genus Physalis - a revision of withasteroids

This review describes results on the chemistry and spectroscopic data of some ergostane derivatives named withasteroids which have been obtained from Physalis genus. The main aim of this report is concerned with the description and characterization of Physalins. These natural product substances are C28 seco steroid lactone type compounds that have been shown biological activities against human illness such as immuno-deficiency, neoplasic tumors, inflammatory process and tropical endemic diseases. Physalins appear to be a source for new drugs to be apply as medicine.

Physalis; Physalins; Withasteroids


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