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Poly (lactide-co-glycolide) acid/poly (lactic acid) blends: in vitro degradation

Plates of the copolymer poly (lactide-co-glycolide) acid have been produced and used as implants that degrade and are absorbed by the organism. Implants that can be absorbed are advantageous in comparison with metallic implants. In this work, plates of the blend poly (lactide- co- glycolide) acid/ poly lactic acid (PLGA/ PLLA) were made and characterized during their in vitro degradation process. It was found that blends are immiscible and that their thermal stability increases with the proportion of PLLA in the blend. The crystallinity degree also increases with the proportion of PLLA in the sample and with degradation time. Besides, it was verified that PLGA is degraded quickly and its presence and amount modifies clearly the morphology of the blends.

Blends; poli(L-lactic acid); poli(L-latic acid-co-glycolic acid); degradation


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