Capillaria hepatica is considered as a parasite that only extremely rarely affects man. However, due to its high prevalence among domestic rodents and the poor housing and hygienic conditions prevailing amongst the low income part of the population, C. hepatica may develop greater chances to cause human infection which may be more important than usually assumed. That is the main reason for this review article in which some data on the biology and pathology of the parasite are presented. The results of some experimental and human studies on the immunopathology of C. hepatica infection are also reported. These indicate that both sensitization and resistance are important features of that parasitic infection.