EFEITOS DO EXERCÍCIO FÍSICO SOBRE DIABETES MELLITUS TIPO 1: UMA REVISÃO SISTEMÁTICA DE ENSAIOS CLÍNICOS E RANDOMIZADOS

Marçal, Danilo Francisco da Silva; Alexandrino, Eduardo Gauze; Cortez, Lucia Elaine Ranieri; Bennemann, Rose Mari

doi:10.4025/jphyseduc.v29i1.2917

Acessibilidade / Reportar erro

Brasil

Journal of Physical Education

Español English

Brasil

Español English

sumário « anterior atual seguinte »

Sumário

Artigo de Revisão • J. Phys. Educ. 29 • 2018 • https://doi.org/10.4025/jphyseduc.v29i1.2917 copiar

EFEITOS DO EXERCÍCIO FÍSICO SOBRE DIABETES MELLITUS TIPO 1: UMA REVISÃO SISTEMÁTICA DE ENSAIOS CLÍNICOS E RANDOMIZADOS

EFFECTS OF PHYSICAL EXERCISE ON TYPE 1 DIABETES MELLITUS: A SYSTEMATIC REVIEW OF CLINICAL AND RANDOMIZED TESTS

Autoria SCIMAGO INSTITUTIONS RANKINGS

RESUMO

Diabetes mellitus tipo 1 (DM1) caracteriza-se como patologia crônica autoimune. Exercício físico (EF) é considerado estratégia positiva no processo terapêutico do DM1. O objetivo do estudo foi avaliar evidências científicas sobre os efeitos do EF em indivíduos com DM1. Trata-se de revisão sistemática de literatura, de estudos clínicos e randomizados. Realizou-se levantamento em periódicos indexados nas bases de dados PUBMED, SCOPUS, COCHRANE, LILACS e SCIELO. Os Descritores em Ciências da Saúde utilizados foram: diabetes mellitus, type 1 AND exercise e seus correspondentes em português e espanhol. Foram incluídos 28 artigos publicados entre os anos de 2012 e 2016. Todos os estudos abordaram a relação entre o gerenciamento da patologia e diferentes tipos, frequência, volume, duração e intensidade de exercícios. Diferentes assuntos foram abordados, como: pâncreas artificiais, dieta, suplementação, insulina e hipoglicemia. Um dos grandes desafios para assegurar boa gestão do DM1 com prática de EF são relacionados ao controle da glicemia e à hipoglicemia durante, logo depois ou tardiamente após a intervenção. Os EF aeróbicos, resistidos, pilates e intermitentes, em conjunto com dieta adequada, horários de refeições e suplementação mostraram-se eficazes no gerenciamento de diversas váriáveis metabólicas e clínicas dos pacientes com DM1.

Palavras-chave:
Diabetes mellitus tipo 1; Exercício; Glicemia; Insulina.

Autor	Ano	Periódico	Assuntos principais
Breton M et al.¹³13. Breton M, Farret A, Bruttomesso D, Anderson S, Magni L, Patek S, et al. Fully integrated artificial pancreas in type 1 diabetes: modular closed-loop glucose control maintains near normoglycemia. Diabetes 2012; 61(9):2230-37.	2012	Diabetes	Pâncreas artificial
Fintini D et al.³⁶36. Fintini D, Di Giacinto B, Brufani C, Cafiero G, Patera PI, Turchetta A, et al. Impaired energy expenditure despite normal cardiovascular capacity in children with type 1 diabetes. Horm Res Paediatr 2012;78(1): 1-7. DOI: 10.1159/000339465. https://doi.org/10.1159/000339465...	2012	Horm. res. Paediatr.	EF / Equilíbrio metabólico
Garg S et al.¹⁷17. Garg SK, et al. Reduction in duration of hypoglycemia by automatic suspension of insulin delivery: the in-clinic ASPIRE study. Diabetes Techonol Ter 2012;14(3):205-9. DOI:10.1089/dia.2011.0292. https://doi.org/10.1089/dia.2011.0292...	2012	Diabetes technol. ther.	Insulina / Hipoglicemia
Maggio ABR et al.²⁶26. Maggio ABR, Rizzoli RR, Marchand LM, Ferrari S, Beghetti M, Farpour-Lambert NJ. Physical activity increases bone mineral density in children with type 1 diabetes. Med Sci Sports Exerc 2012;44(7):1206-11. DOI: 10.1249/MSS.0b013e3182496a25. https://doi.org/10.1249/MSS.0b013e318249...	2012	Med. sci. sports exerc.	EF / DMO
Schimidt S et al.³⁸38. Schmidt S, Finan DA, Duun-Henriksen AK, Jorgensen JB, Madsen H, Bengtsson H, et al. Effects of everyday Life events on glucose, insulin, and glucagon dynamics in continuous subcutaneous insulin infusion-treated type 1 diabetes: collection of clinical data for glucose modeling. Diabetes Technol Ther 2012;14(3):210-17. DOI: 10.1089/dia.2011.0101. https://doi.org/10.1089/dia.2011.0101...	2012	Diabetes technol. ther.	Pâncreas artificial
Tunar M et al.²¹21. Tunar M, Ozen S, Goksen D, Asar G, Bediz CS, Darcan S. The effects of Pilates on metabolic control and physical performance in adolescentes with type 1 diabetes mellitus. J Diabetes Complications 2012;26(4): 348-51. DOI: 10.1016/j.jdiacomp.2012.04.006. https://doi.org/10.1016/j.jdiacomp.2012....	2012	J. diabetes its complicat.	Pilates /Equilíbrio metabólico
Van Bom AC et al.³²32. Van Bom AC, Jonker LD, Koebrugge R, Koops R, Hoekstra JB, DeVries JH. Feasibility of a bihormonal closed-loop system to control postexercise and postprandial glucose excursions. J Diabetes Sci Technol 2012; 6(5):1114-22.	2012	J diabetes sci technol	Pâncreas artificial
Campbell MB et al.¹⁶16. Campbell MD, Walker M, Trenell MI, Jackovljevic DG, Stevenson EJ, Bracken RM, et al. Large pre- and post-exercise rapid-acting insulin reductions preserve glycemia and prevent early- but not late-onset hypoglycemia in patients with type 1 diabetes. Diabetes Care 2013;36(8):2217-24. DOI: 10.2337/dc12-2467. https://doi.org/10.2337/dc12-2467...	2013	Diabetes care	Pâncreas artificial / EF/ Insulina
Davey RJ et al.³⁷37. Davey RJ, Bussau VA, Paramalingam N, Ferreira LD, Mun Lim E, Davis EA, et al. A 10-s Sprint performed after moderate-intensity exercise neither increases nor decreases the glucose requirement to prevent late-onset hypoglycemia in individuals with type1 diabetes. Diabetes Care 2013;36(12):4163-65. DOI:10.2337/dc12-2198. https://doi.org/10.2337/dc12-2198...	2013	Diabetes care	EF / Hipoglicemia
Davey RJ et al.³⁹39. Davey RY, Howe W, Paramalingam M, Ferreira LD, Davis EA, Fournier PA, et al. The effect of midday moderate-intensity exercise on postexercise hypoglycemia risk in individuals with type 1 diabetes. J Clin Endocrinol Metab 2013;98(7):2908-14. DOI: 10.1210/jc.2013-1169. https://doi.org/10.1210/jc.2013-1169...	2013	J Clin Endocrinol Metab.	Horário de EF / Hipoglicemia
Dubé MC et al.⁴⁰40. Dubé MD, Lavaoie C, Weisnagel SJ. Glucose or intermittent high-intensity exercise in glargine/glulisine users with T1DM. Med Sci Sports Exerc 2013;45(1):3-7. DOI: 10.1249/MSS.0b013e31826c6ad3. https://doi.org/10.1249/MSS.0b013e31826c...	2013	Med. sci. sports exerc.	Suplementação / Insulina / Horário EF
Elleri D et al.¹⁰10. Elleri D, Allen JM, Kumareswaran K, Leelarathna L, Nodale M, Caldwell K, et al. Closed-loop basal insulin delivery over 36 hours in adolescents with type 1 diabetes. Diabetes Care 2013;36(4);838-44. DOI:10.2337/dc12-0816. https://doi.org/10.2337/dc12-0816...	2013	Diabetes care	Pâncreas artificial
Fayh APT et al.²⁵25. Fayh APT, Krause M, Rodrigues-Krause J, Ribeiro JL, Ribeiro JP, Friedman R, et al. Effects of L-arginine supplementation on blood flow, oxidative stress status and exercise responses in young adults with uncomplicated type I diabetes. Eur J Nutr 2013;52(3):975-83. DOI: 10.1007/s00394-012-0404-7. https://doi.org/10.1007/s00394-012-0404-...	2013	Eur J Nutr	Suplementação proteica
Haidar A et al.¹²12. Haidar A, Legault L, Dallaire M, Alkhateeb A, Coriati A, Messier V, et al. Glucose-responsive insulin and glucagon delivery (dual-hormone artificial pancreas) in adults with type 1diabetes: a randomized crossover controlled trial. CMAJ 2013;185(4):297-305. DOI: 10.1503/cmaj.121265. https://doi.org/10.1503/cmaj.121265...	2013	CMAJ	Pâncreas artificial /Insulina /Glucagon
Lascar N et al.⁴²42. Lascar N, Kennedy A, Jackson N, Daley A, Downswell G, Thompson D, et al. Exercise to preserve beta cell function in recent-onset type 1 diabetes mellitus (EXTOD) - a study protocol for a pilot randomized controlled trial. Trials 2013;14(1):1-11. DOI: 10.1186/1745-6215-14-180. https://doi.org/10.1186/1745-6215-14-180...	2013	Trials	Preservação de células β
Luijf YM et al.¹¹11. Luijf YM, DeVries JH, Zwinderman K, Leelarathna L, Nodale M, Caldwell K, et al. Day and night closed-loop control in adults with type 1 diabetes: a comparison of two closed-loop algorithms driving continuous subcutaneous insulin infusion versus patient self-management. Diabetes Care 2013:36(12);3882-87. DOI:10.2337/dc12-1956. https://doi.org/10.2337/dc12-1956...	2013	Diabetes care	Pâncreas artificial / Insulina / CG
Yardley J et al.²⁴24. Yardley JE, Kenny GP, Perkins BA, Riddell MC, Balaa N, Malclm J, et al. Resistance versus aerobic exercise. Diabetes Care 2013;36(3):537-42. DOI: 10.2337/dc12-0963. https://doi.org/10.2337/dc12-0963...	2013	Diabetes care	EF aeróbico / EF resistido
Breton M et al.⁹9. Breton MD, Brown SA, Karvetski CH, Kollar L, Topchyan KA, Anderson SM, et al. Adding heart rate signal to a control-to-range artificial pancreas system improves the protection against hypoglycemia during exercise in type 1 diabetes. Diabetes Techonol Ter 2014;16(8):506-11. DOI: 10.1089/dia.2013.0333. https://doi.org/10.1089/dia.2013.0333...	2014	Diabetes technol. ther.	Pâncreas artificia / FC / Hipoglicemia
Campbell MB et al.²⁰20. Campbell MD, Walker M, Trenell MI, Stevenson EJ, Turner D, Bracken RM, et al. A Low-glycemic index meal and bedtime snack prevents postprandial hyperglycemia and associated rises in inflammatory markers, providing protection from early but not late nocturnal hypoglycemia following evening exercise in type 1 diabetes. Diabetes Care 2014;37(7):1845-53. DOI: 10.2337/dc14-0186. https://doi.org/10.2337/dc14-0186...	2014	Diabetes care	Controle glicêmico / Índice glicêmico
Campbell MB et al.¹⁵15. Campbell MD, Walker M, Trenell MI, Luzio S, Dunseath G, Tuner D, et al. Metabolic implications when employing heavy pre- and post-exercise rapid-acting insulin reductions to prevent hypoglycemia in type 1 diabetes patients: a randomised clinical trial. Plos One 2014;9(5):1-9. DOI:0.1371/journal.pone.0097143. https://doi.org/0.1371/journal.pone.0097...	2014	PLOS ONE	Insulina
Danne T et al.¹⁴14. Danne T, Tsioli C, Koordonouri O, Blaesig S, Remus K, Roy A, et al. The PILGRIM Study: in silico modeling of a predictive low glucose management system and feasibility in youth with type 1 diabetes during exercise. Diabetes Techonol Ter . 2014;16(6):338-47. DOI: 10.1089/dia.2013.0327. https://doi.org/10.1089/dia.2013.0327...	2014	Diabetes technol. ther.	Pâncreas artificial / Insulina / Hipoglicemia
Garg S et al.¹⁸18. Garg SK, Brazg RL, Bailey TS, Buckingham BA, Slover RH, Klonoff DC, et al. Hypoglycemia begets hypoglycemia: the order effect in the ASPIRE in-clinic study. Diabetes Technol Ther 2014;16(3):125-30. DOI: 10.1089/dia.2013.0219. https://doi.org/10.1089/dia.2013.0219...	2014	Diabetes technol. ther.	Hipoglicemia
Turner D et al.²³23. Turner D, Luzio S, Kilduff LP, Gray BJ, Dunseath G, Bain SC, et al. Reductions in resistance exercise-induced hyperglycaemic episodes are associated with circulating interleukin-6 in Type 1 diabetes. Diabet Med 2014;31(8):1009-13.	2014	Diabet. med.	Volume de EF resistido
Campbell MB et al.¹⁹19. Campbell MD, Gonzalez JT, Rumbold PL, Walker M, Shaw JA, Stevenson EJ, et al. Comparison of appetite responses to high- and low-glycemic index postexercise meals under matched insulinemia and fiber in type 1 diabetes. Am J Clin Nutr. 2015;101(3):478-86. DOI:10.3945/ajcn.114.097162. https://doi.org/10.3945/ajcn.114.097162...	2015	Am. J. Clin. Nutr.	Dieta / Índice glicêmico
Nguyen T et al.⁴⁵45. Nguyen T, Obeid J, Walker RG, KrauseMP, Hawke TJ, McAssey K, et al. Fitness and physical activity in youth with type 1 diabetes mellitus in good or poor glycemic control. Pediatr Diabetes 2015;16(1):48-7. 10.1111/pedi.12117. https://doi.org/10.1111/pedi.12117...	2015	Pediatr. diabetes.	Aptidão muscular em DM1
Stenerson M et al³⁴34. Stenerson M, Cameron F, Payne SR, Payne SL, Ly TT, Wilson DM, et al. The Impact of Accelerometer use in exercise-associated hypoglycemia prevention in type 1 diabetes. J Diabetes Sci Technol 2015;9(1):80-85. DOI: 10.1177/1932296814551045. https://doi.org/10.1177/1932296814551045... .	2015	J diabetes sci technol	Pâncreas artificia / Insulinal
Wilson DM et al.³³33. Wilson DM, Kalhoum PM, Maahs DM, Chase HP, Messer L, Buckingham BA, et al. Factors associated with nocturnal hypoglycemia in at-risk adolescents and young adults with type 1 diabetes. Diabetes Techonol Ter 2015;17(6):385-91. DOI: 10.1089/dia.2014.0342. https://doi.org/10.1089/dia.2014.0342...	2015	Diabetes technol. ther.	Hipoglicemia
Yardley JE et al.²²22. Yardley JE, Kenny GP, Perkins BA, Riddell MC, Goldfield GS, Donovan L, et al. Resistance exercise in already-active diabetic individuals (READI): study rationale, design and methods for a randomized controlled trial of resistance and aerobic exercise in type 1 diabetes. Contemp Clin Trials 2015;41(4):129-38. DOI: 10.1016/j.cct.2014.12.017. https://doi.org/10.1016/j.cct.2014.12.01...	2015	Contemp. clin. Trials	EF resistido / Equilíbrio metabólico

Universidade Estadual de Maringá Avenida Colombo, 5790 - cep: 87020-900 - tel: 44 3011 4315 - Maringá - PR - Brazil
E-mail: revdef@uem.br

Acompanhe os números deste periódico no seu leitor de RSS

[1] Endereço para correspondência: Danilo Francisco da Silva Marçal. Rua Paraíso 345, Bairro Jardim Marumby, Maringá, PR, CEP 87005-260. E-mail: danilofsm@msn.com