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Well-differentiated papillary mesothelioma of the peritoneum: case report and literature review

Well-differentiated papillary mesothelioma (WDPM) is an uncommon tumor that can be found in peritoneum, usually found as an incidentally small nodular lesion, without symptoms. It is considered an indolent neoplasia, however only a minority of patients presents survival longer than ten years. This report concerns a case of a 44 years-old woman, without history of asbestos exposure; with complaints of ascites, constipation, and a mass in cul-de-sac measuring 5,6 x 6,0 x 8,3cm. The tumor biopsy revealed morphology compatible with WDPM. Due to the impossibility of resection, she was treated with chemotherapy and presents 13 years of survival. Differential diagnosis with serous tumor of ovary was established through imunohistochemistry (CK7+, Calretinin+, CK20-, CEA- and CD15-) and ultrassonography. Considering size of tumor, impossibility of resection and symptomatology, this case has superior survival than described in literature.

Mesothelioma; Pathology; Peritoneum; Well-differentiated papillary mesothelioma; Immunohistochemistry


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