Assumptions on the process of mansoni schistosomiasis transmission areas in Brazilian territory are presented, linking them to the country economical history stages which, at determined time, caused important migratory movements. The same is considered concerning the inserting and spreading of mansoni schistosomiasis transmission areas in São Paulo State, attempting to emphasize some peculiar features of the conduct in its territory, which presents major trend for urbanization, to nearly non-existence of severe forms and peculiar aspects of infection sources and the most prevalent intermediate hosts species in different State regions. Based on these features, it is proposed to divide the São Paulo State territory in three areas regarding to schistosomiasis behaviour, as this measure might constitute subsidies for development of endemic control programmes.
