Bone formation and resorption are continuous processes and a tool to evaluate alterations these activities is to measure seric or urinary markers of bone metabolism. The aims of this study were to identify if commercial sets available to detect human osteocalcin, (OC) amino-terminal propeptides of procollagen type I (PINP), type-I collagen carboxi-terminal telopeptide (ICTP) are also available for usage in domestic cats; measure seric levels of OC, PINP and ICTP; correlate findings with bone mineral density (BMD) in young adult cats. OC and ICTP means (±SD) was 0.15±0.03ng mL-1 and 8.59±5.78ng mL-1, respectively. BMD while 1.40±0.23mm Al. Bone metabolism markers showed low correlation between then and also BMD. This paper concludes that commercial sets designed for OC and ICTP measures in humans may be used for same purpose in cats to evaluate bone metabolism activity alterations and that kits used for PINP in human should not be used to evaluate in cats.
markers; metabolism; bone; osteocalcin; ICTP
