SUMMARY An outbreak of aflatoxicosis in 2 to 6 monthold Duroc swine fed on ration with 519ppb of aflatoxins is reported. Morbidity was 97% and mortality was high but not exactly determined. Clinical signs included feed refusal, poor weight gain or loss of weight, diarrnea and icterus. Subacute and chronic changes were observed in four necropsied pigs. In subacute cases the liver was dark and had depressed hemorrhagic centrilobular areas; there was edema of gallbladder and inspissated bile. In chronic cases the liver was firm orange-yellow and there was yellowish effusions in the organic cavities and edema of the spiral colon. The gastric mucosa of the fundus was dark red. Histologically the subacute changes of the liver were centrilobular necrosis and hemorrhage. hepatocellular megalocytosis, fibrosis, and ductal hyperplasia. In chronic cases there were fibrosis, biliary hyperplasia, hepatomegalocytosis and hepatocellular fatty change. Aflatoxicosis was confirmed up on the clinical signs and lesions, and up on the detection significant levels of aflatoxin on the ration fed to pigs (B1 = 84.3ppb, B2 = 110.8ppb, G1 = 343.7ppb, and G2 = 99.2ppb). Chicks fed the same ration developed aflatoxicosis.
aflatoxins; aflatoxicosis; swine
