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Effect of prolonged-release tapentadol in the management of moderate-to-severe chronic pain in elderly patients. Case reports

ABSTRACT

BACKGROUND AND OBJECTIVES:

Prolonged-release (PR) tapentadol has demonstrated efficacy, safety, and good tolerability for the management of moderate to severe chronic pain in patients over 65 years of age. The objective of this study was to describe three clinical cases in which tapentadol PR was used as treatment of moderate to severe chronic pain in individuals aged 75 to 83 years old.

CASE REPORT:

Two female patients (75 and 83 years old) and one male patient (78 years old) with chronic osteoarticular pain or low back pain of moderate to severe intensities and with functional limitation, who had undergone previous unsuccessful treatments and were functionally limited, underwent treatment with tapentadol PR. Tapentadol PR was associated with considerable improvement of pain in all three patients, leading to greater independence in performing daily activities. In addition, the use of tapentadol PR did not cause any significant adverse effects.

CONCLUSION:

Treatment with tapentadol PR seems to be effective and tolerable in the management of moderate to severe chronic pain in senior patients.

Keywords:
Analgesia; Chronic pain; Elderly; Tapentadol

HIGHLIGHTS

Chronic pain is a highly prevalent condition in senior;

Tapentadol presents a dual mechanism of action that can be considered an option in the management of mixed chronic pain;

Tapentadol prolonged-release appears to be effective, tolerable and safe in the management of chronic pain of moderate to severe intensity in seniors.

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