A field experiment was carried out on a soil rich in organic matter to study the influence of lime and fertilizers on the production of soybean dry matter and on the soil chemical properties. Three rates of lime (2.3, 4.6 and 6.9 t/ha), combined with two rates of superphosphate and one rate of potassium chloride were employed. Molybdenum and boron were also applied in some treatments. Neutralization of Al3+ was not completed 162 days after liming. A time dependent pH variation was observed in the absence and presence of liming. Dry matter and total nitrogen were increased by liming, but no differences were observed among liming rates. In the presence of lime the response to phosphorus was observed at the higher rate but only when potassium was also applied and for the lower liming rate; in the absence of lime only the higher rate of P application was effective, irrespective of the presence of potassium. Applications of K, Mo, and B did not increase the production.