The sugar cane yield response to various combinations of three levels of N-P-K was studied in an experiment carried out on a Glacial type of mixed red soil ("terra-roxa-misturada"), at the Usina Esmeralda, from March 1957 to August 1958. The three levels, 0, 80 and 160 kg/ha of N-P-K were combined as follows: N0P0K0, N0P2K2,N1P2K2, N2P0K2, N2P1K2, N2P2K1, N2P2K0, and N2P2K2. Five replications of the treatments were laid out in ramdomized plots. The results obtained permitted the following conclusions: (a) Phosphorus and nitrogen increased the yeld appreciably and improved the sugar content of the canes; (b) the increase in yield and in sugar content due to potassium was not significant at the 5% level.