Evaluation of the relationship between endolymphatic hydrops and hearing loss in Meniere’s disease based on three-dimensional real inversion recovery sequence

Abstract

Objectives:

The degree of endolymphatic hydrops in Meniere’s disease may be related to hearing loss. However, the results of prior studies have been inconsistent. We aimed to investigate the relationship between endolymphatic hydrops and hearing loss characteristics in Meniere’s disease.

Methods:

This study included 54 patients (62 ears) with Meniere’s disease. Patients underwent three-dimensional real inversion recovery sequences for magnetic resonance imaging and puretone audiometry. Endolymphatic hydrops were assessed according to Gurkov’s criteria (2011). Correlations between different degrees of endolymphatic hydrops and pure-tone audiometry, as well as staging, were analysed.

Results:

Pure tone audiometry and staging were higher for vestibular endolymphatic hydrops complicated by cochlear ones than isolated cochlear or vestibular hydrops (both p<0.05). There was no significant correlation between vestibular endolymphatic hydrops and pure-tonal audiometry or staging (all p > 0.05). The degree of hydrops in the middle turn was correlated with the mid-frequency hearing threshold (p<0.05). The degree of cochlear hydrops was correlated with the audiometry, low-frequency hearing thresholds, mid-frequency hearing thresholds and staging (p<0.01).

Conclusion:

The types and sites of endolymphatic hydrops based on a 3D-real inversion recovery sequence can be used to indicate the degree of hearing loss in patients with Meniere's disease.

Level of evidence:

Level III.

Keywords
Meniere’s disease; Magnetic resonance imaging; Endolymphatic hydrops; Hearing loss

Highlights

Endolymphatic Hydrops (EH) in Meniere’s Disease (MD) may be related to hearing loss.

We investigated the relationship between EH and hearing loss characteristics in MD.

Type and site of EH based real IR sequence can indicate the degree of hearing loss in MD.