Symptoms of COVID-19 in children

Melo, M.M.; Neta, M.M.R.; Neto, A.R.S.; Carvalho, A.R.B.; Magalhães, R.L.B.; Valle, A.R.M.C.; Ferreira, J.H.L.; Aliaga, K.M.J.; Moura, M.E.B.; Freitas, D.R.J.

doi:10.1590/1414-431X2022e12038

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Brazilian Journal of Medical and Biological Research

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Review • Braz. J. Med. Biol. Res. 55 • 2022 • https://doi.org/10.1590/1414-431X2022e12038 copy

Symptoms of COVID-19 in children

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The aim of this study was to review the symptomatic manifestations of COVID-19 in children in the scientific literature. An integrative review of studies published between December 2019 and September 5, 2021, from the Medical Literature Analysis and Retrieval System Online, Web of Science, Scopus, Literatura Latino-Americana em Ciência de Saúde, and Base de Dados de Enfermagem databases, was carried out to answer the following research question: What symptomatic manifestations does COVID-19 cause in children?”. Twenty articles were included. The main symptoms described were fever, cough, diarrhea, vomiting, sore throat, dyspnea, headache, abdominal pain, malaise, and weakness or tiredness. The findings of this review can contribute to the diagnosis and clinical decision-making of the health team by providing information that facilitates the identification of COVID-19 in the target population, favoring early identification, better care, and consequently a better prognosis.

COVID-19; SARS-CoV-2; Symptoms; Children; Diagnosed cases

Database	Search Strategy
MEDLINE (PubMed)	((((“Child”[Mesh]) OR (“child”[All Fields])) OR (“children”[All Fields])) AND (((“Signs and Symptoms”[Mesh]) OR (“signs and symptoms”[All Fields])) OR (“symptoms and signs”[All Fields]))) AND (((((((((((((“COVID-19”[Mesh]) OR (“COVID-19”)) OR (“SARS-CoV-2”[Mesh])) OR (“SARS-CoV-2”)) OR (“covid 19”[All Fields])) OR (“COVID-19 Virus Disease”)) OR (“COVID-19 Virus Infection”)) OR (“2019-nCoV Infection”)) OR (“Coronavirus Disease-19”)) OR (“2019 novel coronavirus disease”[All Fields])) OR (“2019 novel coronavirus infection”[All Fields])) OR (“2019-nCoV Disease”)) OR (“SARS-CoV-2 Infection”))
Scopus (Elsevier)	((TITLE-ABS-KEY (“Child”)) OR (TITLE-ABS-KEY (“Children”))) AND ((TITLE-ABS-KEY (“Signs and Symptoms”)) OR (TITLE-ABS-KEY (“Symptoms and Signs”))) AND ((TITLE-ABS-KEY (“COVID-19”)) OR (TITLE-ABS-KEY (“SARS-CoV-2”)) OR (TITLE-ABS-KEY (“COVID 19”)) OR (TITLE-ABS-KEY (“COVID-19 Virus Disease”)) OR (TITLE-ABS-KEY (“COVID-19 Virus Infection”)) OR (TITLE-ABS-KEY (“2019-nCoV Infection”)) OR (TITLE-ABS-KEY (“Coronavirus Disease-19”)) OR (TITLE-ABS-KEY (“2019 Novel Coronavirus Disease”)) OR (TITLE-ABS-KEY (“2019 Novel Coronavirus Infection”)) OR (TITLE-ABS-KEY (“2019-nCoV Disease”)) OR (TITLE-ABS-KEY (“SARS-CoV-2 Infection”)))
Web of Science	TS=(“Child”) OR TS=(“Children”) AND TS=(“Signs and Symptoms”) OR TS=(“Symptoms and Signs”) AND TS=(“COVID-19”) OR TS=(“SARS-CoV-2”) OR TS=(“COVID 19”) OR TS=(“COVID-19 Virus Disease”) OR TS=(“COVID-19 Virus Infection”) OR TS=(“2019-nCoV Infection”) OR TS=(“Coronavirus Disease-19”) OR TS=(“2019 Novel Coronavirus Disease”) OR TS=(“2019 Novel Coronavirus Infection”) OR TS=(“2019-nCoV Disease”) OR TS=(“SARS-CoV-2 Infection”)
LILACS and BDENF (BVS)	((mh:(“Criança”)) OR (“Criança”) OR (mh:(“Child”)) OR (“Child”) OR (mh:(“Nião”)) OR (“Nião”) OR (“Crianças”) OR (“Niãos”)) AND ((mh:(“Sinais e Sintomas”)) OR (“Sinais e Sintomas”) OR (mh:(“Signs and Symptoms”)) OR (“Signs and Symptoms”) OR (mh:(“Signos y Síntomas”)) OR (“Signos y Síntomas”) OR (“Manifestações Clínicas”) OR (“Observação Clínica”) OR (“Sinais Clínicos”) OR (“Sintoma”) OR (“Sintoma Clínico”) OR (“Manifestaciones Clínicas”) OR (“Observación Clínica”) OR (“Quejas y Síntomas”) OR (“Signo Clínico”) OR (“Síntoma Clínico”) OR (“Síntomas y Quejas”)) AND ((mh:(“Infecções por Coronavirus”)) OR (“Infecções por Coronavirus”) OR (mh:(“Coronavirus Infections”)) OR (“Coronavirus Infections”) OR (mh:(“Infecciones por Coronavirus”)) OR (“Infecciones por Coronavirus”) OR (“COVID-19”) OR (“Doença pelo Novo Coronavírus (2019-nCoV)”) OR (“Doença por Coronavírus 2019-nCoV”) OR (“Febre de Pneumonia por Coronavírus de Wuhan”) OR (“Infecção pelo Coronavírus 2019-nCoV”) OR (“Pneumonia por Novo Coronavírus de 2019-2020”))

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[1] Correspondence: A.R.S. Neto: antonioneto@ufpi.edu.br