Eugenia uniflora
|
Essential oil |
β - Elemene, Caryophyllene, D-Germacrene, Bicyclogermacrene, α-Bulnesene, Germacrene B, Selina-1,3,7(11)-trien-8-one, Germacrone, selina-1,3,7(11)-trien-8-one epoxide |
Antifungal activity and virulence inhibition against Candida albicans, C. tropicalis and C. krusei
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High concentrations of essential oil were required to obtain an antifungal effect, with no synergism on the combination with fluconazole - regardless, good results were obtained in relation to C. albicans and C. tropicalis
|
(Santos et al., 2018SANTOS, J.F.S., ROCHA, J.E., BEZERRA, C.F., DO NASCIMENTO SILVA, M.K., DE MATOS, Y.M.L.S., DE FREITAS, T.S. and MORAIS-BRAGA, M.F.B., 2018. Chemical composition, antifungal activity and potential anti-virulence evaluation of the Eugenia uniflora essential oil against Candida spp. Food Chemistry, vol. 261, pp. 233-239. http://dx.doi.org/10.1016/j.foodchem.2018.04.015. PMid:29739588. http://dx.doi.org/10.1016/j.foodchem.201...
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Lippia gracilis
|
Essential oil, and essential oil emulsions |
α-Thujene α-Pinene. Mircene, α Terpinene, p-Cimene, Limonene 1,8 Cineol, γ-Terpinene, Linalol, Terpinen-4-ol Metyl tymol, Tymol, Carvacrol, β-Cariofilene, α-Humulene, Viridiflorene, Biciclogermacrene, Espathulenol, Caryophyllene Oxide |
Antifungal activity of the oil and its nanoemulsions against Thielaviopis paradoxa
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MIC was 0.23 ± 0.3 mg/mL, and MFC 0.80 ± 0.08 mg/mL, the fungicide potential was maintained at the nanoemulsion developed. |
(Cruz et al., 2018CRUZ, E.M., MENDONÇA, M.C., BLANK, A.F., SAMPAIO, T.S., PINTO, J.A., GAGLIARDI, P.R. and WARWICK, D.R., 2018. Lippia gracilis Schauer essential oil nanoformulation prototype for the control of Thielaviopis paradoxa. Industrial Crops and Products, vol. 117, pp. 245-251. http://dx.doi.org/10.1016/j.indcrop.2018.02.068. http://dx.doi.org/10.1016/j.indcrop.2018...
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Lippia alba
|
Essential oil of leaves |
Marjority: 6-methy-5-hepten-2-one, nerol/geraniol, citral (neral/geranial), E-caryophyllene |
Antimicrobial activity (antifungal and antibacterial) against 16 microorganisms, and cytotoxic activity against cell lines B16F10Nex2, MCF-7, HUVEC, CT26WT, A549, MDA-MB-231, CACO 2, and CHO. |
Cytotoxic activity was observed in tumor cell lines B16F10Nex2 and A549. The essential oil showed activity in all yeasts strains, except C. albicans. |
(Santos et al., 2016SANTOS, N.O.D., PASCON, R.C., VALLIM, M.A., FIGUEIREDO, C.R., SOARES, M.G., LAGO, J.H.G. and SARTORELLI, P., 2016. Cytotoxic and antimicrobial constituents from the essential oil of Lippia alba (Verbenaceae). Medicines (Basel, Switzerland), vol. 3, no. 3, pp. 22. http://dx.doi.org/10.3390/medicines3030022. PMid:28930132. http://dx.doi.org/10.3390/medicines30300...
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R. echinus Schauer |
Essential oil |
Marjority: β-Caryophyllene and bicyclogermacrene |
Antifungical activity against Candida albicans, C. krusei and tropicalis, and E. coli,
|
The essential oil itself was not relevant for clinical use, but it showed capability to enhance antibacterial and antifungal activity of nystatin and fluconazole. |
(Duarte et al., 2016DUARTE, A.E., DE MENEZES, I.R.A., BEZERRA MORAIS BRAGA, M.F., LEITE, N.F., BARROS, L.M., WACZUK, E.P. and ESCOBAR BURGER, M., 2016. Antimicrobial activity and Modulatory effect of essential oil from the leaf of Rhaphiodon echinus (Nees & Mart) Schauer on some antimicrobial drugs. Molecules (Basel, Switzerland), vol. 21, no. 6, pp. 743. http://dx.doi.org/10.3390/molecules21060743. PMid:27338314. http://dx.doi.org/10.3390/molecules21060...
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Eremanthus arboreus
|
Essential oils |
Main component: α-Bisabolol |
Chemical composition and literature review of its antimicrobial activities |
As the main component of the essential oil, is α-Bisabolol, it has pharmaceutical potential to present antimicrobial, larvicide, anti-inflammatory and antinociceptive. |
(Macedo et al., 2020MACEDO, G.F., ALMEIDA-BEZERRA, J.W., DA SILVA, V.B., LIMA, E.E., DE MENEZES, S.A., PORTELA, B.Y.M., BRAGA, B.L.P., BEZERRA, J.S., OLIVEIRA, M.G., ALENCAR, D.R., COSTA, A.R., SOUZA, M.A., CRUZ NETO, J., PEREIRA, T.C. and SILVA, F.S.H., 2020. Eremanthus arboreus (Gardner) MacLeish (Candeeiro): natural source of α-Bisabolol. Research, Social Development, vol. 9, no. 10, pp. e9599109270. http://dx.doi.org/10.33448/rsd-v9i10.9270. http://dx.doi.org/10.33448/rsd-v9i10.927...
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Lippia gracilis
|
Leaves/hydrodistilled |
Carvacrol, thymol |
Antifungal activity |
The biomass formation of the F. oxysporum biofilm was inhibited completely at essential oils concentrations ranging from 0.3125 to 10 mg ml−1 . |
(Oliveira et al., 2021OLIVEIRA, T.N.S., SILVA‐FILHO, C.M.S., MALVEIRA, E.A., AGUIAR, T.K.B., SANTOS, H.S., ALBUQUERQUE, C.C. and VASCONCELOS, M.A., 2021. Antifungal and antibiofilm activities of the essential oil of leaves from Lippia gracilis Schauer against phytopathogenic fungi. Journal of Applied Microbiology, vol. 130, no. 4, pp. 1117-1129. http://dx.doi.org/10.1111/jam.14857. PMid:32961612. http://dx.doi.org/10.1111/jam.14857...
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Lippia sidoides, Lippia gracilis
|
Leaves/hydrodistillation |
Thymol, carvacrol |
Antifungal activity |
At concentrations of 0.3 µL mL-1, both the essential oils of L. gracilis and L. sidoides inhibited 100% mycelial growth of Colletotrichum sp.
|
(Araújo et al., 2018ARAÚJO, J.M.S., DE SIQUEIRA, A.C.P., BLANK, A.F., NARAIN, N. and DE AQUINO SANTANA, L.C.L., 2018. A cassava starch–chitosan edible coating enriched with Lippia sidoides Cham. essential oil and pomegranate peel extract for preservation of Italian tomatoes (Lycopersicon esculentum Mill.) stored at room temperature. Food and Bioprocess Technology, vol. 11, no. 9, pp. 1750-1760. http://dx.doi.org/10.1007/s11947-018-2139-9. http://dx.doi.org/10.1007/s11947-018-213...
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Eugenia uniflora L. |
Leaves/hydro-distillation |
Mono- and sesquiterpenes |
Antifungal activity and potential anti-virulence |
The concentration that reduced microorganismal growth was ≥8,192 μg/mL while the IC50 varied, this being between 1892.47 and 12491.80 μg/ mL (oil), 10.07 – 80.78 μg/mL (fluconazole) and 18.53 – 295.60 μg/mL (fluconazole + oil). 295.60 μg/mL (fluconazole + oil). |
(Santos et al., 2018SANTOS, J.F.S., ROCHA, J.E., BEZERRA, C.F., DO NASCIMENTO SILVA, M.K., DE MATOS, Y.M.L.S., DE FREITAS, T.S. and MORAIS-BRAGA, M.F.B., 2018. Chemical composition, antifungal activity and potential anti-virulence evaluation of the Eugenia uniflora essential oil against Candida spp. Food Chemistry, vol. 261, pp. 233-239. http://dx.doi.org/10.1016/j.foodchem.2018.04.015. PMid:29739588. http://dx.doi.org/10.1016/j.foodchem.201...
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Lippia alba (Mill.) N.E.Br. ex Britton & P. Wilson (Verbenaceae) |
Leaves/hydro-distillation |
Linalool, trans-ocimenone and caryophyllene oxide |
Antifungal activity |
The essential oils showed antifungal activity, mainly against S. slerotiorum, a fungi species related with diseases in soybean plants, with 100% of growth inhibition. |
(Arruda et al., 2019ARRUDA, R.D.C.O., VICTÓRIO, C.P., BOARETTO, A.G., CAROLLO, C.A., DA SILVA FARIAS, C., MARCHETTI, C.R. and SILVA, D.B., 2019. Essential oil composition, antifungal activity and leaf anatomy of Lippia alba (Verbenaceae) from Brazilian Chaco. Journal of Medicinal Plants Research, vol. 13, no. 4, pp. 79-88. http://dx.doi.org/10.5897/JMPR2018.6700. http://dx.doi.org/10.5897/JMPR2018.6700...
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Croton tricolor
|
Stems/hydrodistillation |
Epiglobulol, α-bisabolol, α-trans-bergamotol and β-caryophyllene. |
Antifungal activity |
Essential oils concentrations from 1.0 to 1024 μg/mL inhibited the growth of all tested strains, |
(Miranda et al., 2019MIRANDA, F.M., BRAGA DO NASCIMENTO JUNIOR, B., AGUIAR, R.M., PEREIRA, R.S., DE OLIVEIRA TEIXEIRA, A., DE OLIVEIRA, D.M. and FROLDI, G., 2019. Promising antifungal activity of Croton tricolor stem essential oil against Candida yeasts. The Journal of Essential Oil Research, vol. 31, no. 3, pp. 223-227. http://dx.doi.org/10.1080/10412905.2018.1539416. http://dx.doi.org/10.1080/10412905.2018....
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Nectandra, and Ocotea genera |
Seeds, leaves, stem barks, and twigs/ hydrodistillation |
β-caryophyllene, germacrene D, bicyclogermacrene, caryophyllene oxide, α-bisabolol, bicyclogermacrenal, phenylpropanoids, safrole, 6-methoxyelemicin, apiole, limonene, α-pinene, β-pinene, 1,8-cineole, and camphor. |
Antimicrobial activity |
Several biological activities have been attributed to these oils, especially cytotoxic, antioxidant and antifungal potential, among other pharmacological applications. |
(Xavier et al., 2020XAVIER, J.K.A., ALVES, N.S.F., SETZER, W.N. and DA SILVA, J.K.R., 2020. Chemical diversity and Rogical activities of essential oils from Licaria, Nectrandra and Ocotea Species (Lauraceae) with occurrence in Brazilian biomes. Biomolecules, vol. 10, no. 6, pp. 869. http://dx.doi.org/10.3390/biom10060869. PMid:32517106. http://dx.doi.org/10.3390/biom10060869...
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Mentha piperita L. |
Essential oils, and citral and limonene |
The chemical nature of the essential oils were not studied. Citral and Limonene. |
Screening and selection the best product with antifungal activity against C. albicans strains isolated from dental prostheses |
Of all essential oils and molecules, citral presented the best antifungal activity, against strains nystatin resistant |
(Freire et al., 2017FREIRE, J.C.P., JÚNIOR, J.K.D.O., SILVA, D.D.F., SOUSA, J.P.D., GUERRA, F.Q.S. and DE OLIVEIRA LIMA, E., 2017. Antifungal activity of essential oils against Candida albicans strains isolated from users of dental prostheses. Evidence-Based Complementary and Alternative Medicine, vol. 2017, pp. 7158756. http://dx.doi.org/10.1155/2017/7158756. PMid:29234423. http://dx.doi.org/10.1155/2017/7158756...
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Algrizea minor
|
The essential oil was extracted by hydrodistillation of the leaves |
b-Pinene and a-Pinene (monoterpene) |
The antimicrobial activity of Algrizea minor essential oil, which contains as main constituents b-Pinene and a-Pinene |
Candida albicans ATCC 10231 (500 mg/mL) and Candida glabrata ATCC 15126 (1000 mg/mL) |
(Veras et al., 2020VERAS, B.O., DOS SANTOS, Y.Q., OLIVEIRA, F.G.D.S., ALMEIDA, J.R.G.D.S., DA SILVA, A.G., CORREIA, M.T.D.S. and DA SILVA, M.V., 2020. Algrizea Minor Sobral, Faria & Proença (Myrteae, Myrtaceae): chemical composition, antinociceptive, antimicrobial and antioxidant activity of essential oil. Natural Product Research, vol. 34, no. 20, pp. 3013-3017. http://dx.doi.org/10.1080/14786419.2019.1602832. PMid:31014086. http://dx.doi.org/10.1080/14786419.2019....
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Schinus terebinthifolia
|
Essential oils from leaves by hydrodistillation |
Terpenes |
Antichemotactic and Antifungal Action of the Essential Oils from Cryptocarya aschersoniana, Schinus terebinthifolia, and Cinnamomum amoenum
|
Resulting in MIC ranging from 125 μg/mL to over 500 μg/mL. C. aschersoniana oil inhibited the growth of species of the genera Trichophyton and Microsporum and combined terbinafine resulted in an additive interaction effect |
(Maciel et al., 2019MACIEL, A.J., LACERDA, C.P., DANIELLI, L.J., BORDIGNON, S.A., FUENTEFRIA, A.M. and APEL, M.A., 2019. Antichemotactic and antifungal action of the essential oils from Cryptocarya aschersoniana, Schinus terebinthifolia, and Cinnamomum amoenum. Chemistry & Biodiversity, vol. 16, no. 8, pp. e1900204. http://dx.doi.org/10.1002/cbdv.201900204. PMid:31298500. http://dx.doi.org/10.1002/cbdv.201900204...
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Eugenia uniflora
|
Leaves extract |
Terpenes |
Antifungal potential of plant species from brazilian caatinga against. Dermatophytes. |
An inhibitory effect on dermatophytes growth was observed for essential oil from leaves of E. uniflora cultivated in the Brazilian cerrado for AcE of E. uniflora, which exhibited moderate activity against most clinical isolates (MIC90 of 125.0 µg/mL) |
(Biasi-Garbin et al., 2016BIASI-GARBIN, R.P., DEMITTO, F.D.O., AMARAL, R.C.R.D., FERREIRA, M.R.A., SOARES, L.A.L., SVIDZINSKI, T.I.E. and YAMADA-OGATTA, S.F., 2016. Antifungal potential of plant species from Brazilian Caatinga against dermatophytes. Revista do Instituto de Medicina Tropical de São Paulo, vol. 58, pp. 18. http://dx.doi.org/10.1590/S1678-9946201658018. PMid:27007561. http://dx.doi.org/10.1590/S1678-99462016...
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