Somatosensory evoked potential in children with epileptic seizures and centrotemporal and evoked spikes on EEG

SOMATOSENSORY EVOKED POTENTIAL IN CHILDREN WITH EPILEPTIC SEIZURES AND CENTROTEMPORAL AND EVOKED SPIKES ON EEG (ABSTRACT)^*. THESIS. CAMPINAS, 2000.

GLÓRIA MARIA ALMEIDA SOUZA TEDRUS^**

The present research refers to latencies and amplitudes of cortical components of somatosensory evoked potential through median and posterior tibial nerve stimulation in a group of 20 children with partial idiopathic epilepsy and somato-sensitive evoked spikes on the EEG (one sub-group with benign childhood epilepsy with centrotemporal spikes, 8 cases; another sub-group with other partial idiopathic epilepsies, 12 cases) and compared to latencies and amplitudes of cortical components of 20 normal children and 20 children with benign childhood epilepsy with centrotemporal spikes, but without spikes evoked through somatosensory stimulation.

It was therefore possible to demonstrate that:

1. Latency of cortical components of children with epileptic seizures is similar to that of normal children;

2. One or more of the components N45, N75, P98 and/or N126 (posterior tibial nerve) with high amplitude occur: in most patients with partial idiopathic childhood epilepsy and with spikes evoked through somatosensory stimulation; in significant proportion in children with benign childhood epilepsy with centrotemporal spikes and without spikes evoked through somatosensory stimulation; and, in greater proportion in children with partial idiopathic childhood epilepsies with spikes evoked through somatosensory stimulation than in children with benign childhood epilepsy with centrotemporal spikes, but without evoked spikes and, in these children, in greater proportion than in normal children.

3. Amplitude of component N35 (median nerve) is greater in children with benign childhood epilepsy with centrotemporal spikes and without spikes evoked through somatosensory stimulation than in normal children;

4. Amplitude of component N98, obtained through posterior tibial nerve stimulation is greater in children with partial idiopathic epilepsy and with spikes evoked through somatosensory stimulation than in normal children and in those children with benign childhood epilepsy with centrotemporal spikes and without evoked spikes;

5. High amplitude (higher than 7 µV) of component N35 is more commonly found in children with benign childhood epilepsy with centrotemporal spikes, with or without evoked spikes, than in children with other partial idiopathic epilepsies and with evoked spikes;

6. High amplitude (higher than 7 µV) of component N60 (median nerve) is more frequently found in individuals with benign childhood epilepsy with centrotemporal spikes and without evoked spikes or, further, in those with partial idiopathic childhood epilepsies and with spikes evoked through somatosensory stimulation than in normal individuals;

7. There is no correlation between lateralization of epileptiform activity and that of cortical components N35 and P98 with elevated amplitude;

8. PES can contribute to neurophysiological investigation of partial idiopathic childhood epilepsies.

KEY WORDS: somatosensory evoked potential, benign childhood epilepsy with centrotemporal spikes, EEG evoked spikes.

**Address: Rua Sebastião de Souza 205 / 122. 13020-020 Campinas SP, Brasil.

*

Potencial evocado somato-sensitivo em crianças com epilepsias benignas parciais da infância e pontas evocadas por estímulos somato-sensitivos no eletrencefalograma (Resumo). Tese de Doutorado, Faculdade de Ciências Médicas da Universidade Estadual de Campinas ¾ UNICAMP (Área: Neurologia).Orientadora: Elizabeth M.A.B. Quagliato.

Publication Dates

• Publication in this collection
  05 Oct 2001
• Date of issue
  Sept 2001