The central pontine myelinosis is classically related with rapid correction of chronic hyponatremia. Recently, important aditional factors have been described in the pathogenesis of this condition. We report the case of a 43-year-old alcoholic malnourished man, with acute renal failure with dialytic treatment, and output failure Shoshin beriberi. He had tetraplegy and coma. Confirmation of pontine and extrapontine myelinosis by magnetic resonance imaging, and abnormalities on auditive evoked potentials are described.
central pontine and extra-pontine myelinosis; alcoholism; Shoshin beriberi
